The Journal of Antibiotics seeks to promote research on antibiotics and related types of biologically active substances and publishes Articles, Review Articles, Brief Communication, Correspondence and other specially commissioned reports. The Journal of Antibiotics accepts papers on biochemical, chemical, microbiological and pharmacological studies. However, studies regarding human therapy do not fall under the journal’s scope. Contributions regarding recently discovered antibiotics and biologically active microbial products are particularly encouraged. Topics of particular interest within the journal's scope include, but are not limited to, those listed below: Discovery of new antibiotics and related types of biologically active substances Production, isolation, characterization, structural elucidation, chemical synthesis and derivatization, biological activities, mechanisms of action, and structure-activity relationships of antibiotics and related types of biologically active substances Biosynthesis, bioconversion, taxonomy and genetic studies on producing microorganisms, as well as improvement of production of antibiotics and related types of biologically active substances Novel physical, chemical, biochemical, microbiological or pharmacological methods for detection, assay, determination, structural elucidation and evaluation of antibiotics and related types of biologically active substances Newly found properties, mechanisms of action and resistance-development of antibiotics and related types of biologically active substances.
《抗生素杂志》致力于促进抗生素和相关类型生物活性物质的研究，并发表文章、综述文章、简短交流、通信和其他特别委托的报告。《抗生素杂志》接受有关生物化学、化学、微生物学和药理学研究的论文。然而，关于人类治疗的研究并不属于该杂志的范围。特别鼓励对最近发现的抗生素和生物活性微生物产品作出贡献。本期刊的研究范围包括但不限于下列主题：新抗生素及其相关类型生物活性物质的发现抗生素及其相关类型生物活性物质的生产、分离、表征、结构解析、化学合成和衍生、生物活性、作用机制和构效关系生产微生物的生物合成、生物转化、分类学和遗传学研究，以及抗生素及其相关类型生物活性物质生产的改进抗生素及其相关类型生物活性物质的检测、分析、测定、结构解析和评价的新物理、化学、生物化学、微生物或药理学方法抗生素及其相关类型生物活性物质的新发现性质、作用机制和耐药性发展。
Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors
来源期刊：The Journal of antibioticsDOI：10.1038/s41429-019-0171-2
Global Internet Data on the Interest in Antibiotics and Probiotics Generated by Google Trends
来源期刊：The Journal of AntibioticsDOI：10.3390/ANTIBIOTICS8030147
Synergistic combinations of anthelmintic salicylanilides oxyclozanide, rafoxanide, and closantel with colistin eradicates multidrug-resistant colistin-resistant Gram-negative bacilli
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0186-8
Novel 5-substituted derivatives of 2’-deoxy-6-azauridine with antibacterial activity
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0158-z
Diaporone A, a new antibacterial secondary metabolite from the plant endophytic fungus Diaporthe sp.
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0251-3
High-throughput identification of the sensitivities of an Escherichia coli ΔrecA mutant strain to various chemical compounds
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0160-5
Regioselective single pot C3-glycosylation of strophanthidol using methylboronic acid as a transient protecting group
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0172-1
Doxycycline inhibits pre-rRNA processing and mature rRNA formation in E. coli
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0149-0
Identification of novel in vitro antibacterial action of cloprostenol and evaluation of other non-antibiotics against multi-drug resistant A. baumannii
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0244-2
Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0194-8
New semisynthetic teicoplanin derivatives have comparable in vitro activity to that of oritavancin against clinical isolates of VRE
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0164-1
Secondary metabolites produced by the citrus phytopathogen Phyllosticta citricarpa
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0154-3
Tunicamycin: chemical synthesis and biosynthesis
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0200-1
Antimicrobial anthraquinones from cultures of the ant pathogenic fungus Cordyceps morakotii BCC 56811
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-018-0135-y
Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0216-6
Rescrutiny of the sansanmycin biosynthetic gene cluster leads to the discovery of a novel sansanmycin analogue with more potency against Mycobacterium tuberculosis
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0210-z
Two new secondary metabolites from a mangrove-derived fungus Cladosporium sp. JS1-2
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0206-8
Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The discovery of liposidomycin and related compounds with a perspective on their application to new antibiotics
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0241-5
Synthesis and biological evaluation of (±)-hippolachnin and analogs
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0176-x
New azaphilones from Penicillium variabile, a fungal endophyte from roots of Aconitum vilmorinianum
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0250-4
Muraminomicins, new lipo-nucleoside antibiotics from Streptosporangium sp. SANK 60501-structure elucidations of muraminomicins and supply of the core component for derivatization
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0215-7
Coumamarin: a first coumarinyl calcium complex isolated from nature
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0207-7
Three new polyketides from a mangrove-derived fungus Colletotrichum gloeosporioides
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0178-8
Amycolatopsis alkalitolerans sp. nov., isolated from Gastrodia elata Blume
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0222-8
Fosfomycin and Staphylococcus aureus: transcriptomic approach to assess effect on biofilm, and fate of unattached cells
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0256-y
Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0229-1
Formal syntheses of (−)-isoretronecanol, (+)-laburnine, and a concise enantioselective synthesis of (+)-turneforcidine
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0169-9
De novo synthesis of novel bacterial monosaccharide fusaminic acid
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0170-3
Synthesis and biological activity of analogs of CPZEN-45, a novel antituberculosis drug
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0225-5
Antimicrobial Activity of Substituted Benzopentathiepin-6-amines
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0191-y
Cipralphelin, a new anti-oxidative N-cinnamoyl tripeptide produced by the deep sea-derived fungal strain Penicillium brevicompactum FKJ-0123
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0208-6
An inoculum-dependent culturing strategy (IDC) for the cultivation of environmental microbiomes and the isolation of novel endophytic Actinobacteria
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0226-4
Synergistic enhancement of beta-lactam antibiotics by modified tunicamycin analogs TunR1 and TunR2
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0220-x
Complete NMR assignment and absolute configuration of k4610422, a norditerpenoid inhibitor of testosterone-5α-reductase originally from Streptosporangium: rediscovery from a thermophilic Actinomadura
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0231-7
Isolation of depsipeptides and optimization for enhanced production of valinomycin from the North-Western Himalayan cold desert strain Streptomyces lavendulae
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0183-y
Chiral aminophosphines derived from hydroxyproline and their application in allene–imine [4\u2009+\u20092] annulation
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0181-0
Design, synthesis and antimicrobial studies of some polymyxin analogues
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0262-0
Design, synthesis, and antibacterial evaluation of novel derivatives of NPS-2143 for the treatment of methicillin-resistant S. aureus (MRSA) infection
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0177-9
Albicidin, a potent DNA gyrase inhibitor with clinical potential
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0228-2
A transannular approach toward lycopodine synthesis
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0155-2
Novel adenosine-derived inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0199-3
Construction of a 6/5/9-membered tricyclic structure of cladiellins via radical-polar crossover reaction
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0150-7
A letter from Professor Samuel J. Danishefsky
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0179-7
Professor Samuel J. Danishefsky, extraordinary synthetic chemist and great mentor
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0173-0
In honor of Professor Samuel J. Danishefsky
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0182-z
Sequential exo-mode oxacyclizations for the synthesis of the CD substructure of brevenal
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-018-0124-1
Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0263-z
In vitro activity of eravacycline in combination with colistin against carbapenem-resistant A. baumannii isolates
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0188-6
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma
来源期刊：The Journal of antibioticsDOI：10.1038/s41429-019-0167-y
A new indole glycoside from Kitasatospora sp. MG372-hF19 carrying a 6-deoxy-α-l-talopyranose moiety
来源期刊：The Journal of AntibioticsDOI：10.1038/s41429-019-0258-9
