The Journal of Allergy and Clinical Immunology publishes high-impact, cutting-edge clinical and translational research papers for allergists, immunologists, dermatologists, gastroenterologists, and other physicians and researchers interested in allergic diseases and clinical immunology. Articles cover such topics as asthma, food allergy, allergic rhinitis, atopic dermatitis, primary immune deficiencies, occupational and environmental allergy, and other allergic and immunologic diseases, and include clinical trials and mechanistic studies that report on novel therapies, insights into underlying mechanisms, and other discoveries that will inform our understanding of these diseases and ultimately improve the diagnosis and management of patients. With an impact factor of 14.110, the journal ranks 1st of 27 in the Allergy category and 6th of 158 in the Immunology category in the 2018 Journal Citation Reports®, published by Clarivate. The Journal of Allergy and Clinical Immunology is also recommended for initial purchase in the Brandon-Hill study, Selected List of Books and Journals for the Small Medical Library.
《变态反应和临床免疫学杂志》为变态反应学家、免疫学家、皮肤科医生、胃肠病学家以及其他对变态反应疾病和临床免疫学感兴趣的医生和研究人员发表具有高影响力的、前沿的临床和转化研究论文。文章涵盖了哮喘、食物过敏、过敏性鼻炎、特应性皮炎、原发性免疫缺陷、职业和环境过敏以及其他过敏性和免疫性疾病等主题，并包括报告新疗法的临床试验和机制研究、对潜在机制的见解以及其他发现，这些发现将有助于我们了解这些疾病，并最终改善患者的诊断和管理。在Clarivate出版的2018年Journal Citation Reports®中，该杂志以14.110的影响因子在过敏类27个类别中排名第1，在免疫类158个类别中排名第6。《过敏与临床免疫学杂志》也被推荐为Brandon-Hill研究中的首次购买，《小型医学图书馆图书和期刊精选清单》。
STING-associated lung disease in mice relies on T cells but not type I interferon.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.01.044
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.05.002
Multicenter, randomized, double‐blind, placebo‐controlled clinical trial of vital wheat gluten oral immunotherapy
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.08.041
Allergic conversion of protective mucosal immunity against nasal bacteria in patients with chronic rhinosinusitis with nasal polyposis
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.07.006
Ormdl3 and Allergic Asthma: from Physiology to Pathology.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.07.023
B lymphocytes directly contribute to tissue fibrosis in IgG4-Related Disease.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.07.004
IL-33trap is a novel IL-33-neutralizing biologic that inhibits allergic airway inflammation.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.02.028
Human cystatin SN is an endogenous protease inhibitor that prevents allergic rhinitis
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.06.035
B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.02.010
Regulatory cells in the skin: Pathophysiologic role and potential targets for anti-inflammatory therapies.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2018.12.1011
Macrophage polarization: Reaching across the aisle?
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2018.12.995
Combined Immunodeficiency due to a loss of function mutation in DNA Polymerase Delta 1.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.10.004
Loss of GTPase of immunity‐associated protein 5 (Gimap5) promotes pathogenic CD4+ T‐cell development and allergic airway disease
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.10.018
HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.06.034
E-cigarettes, Vaping-Related Pulmonary Illnesses, and asthma: A Perspective from Inhalation Toxicologists.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.11.001
Cell-Based Biosensors For Immunology, Inflammation, and Allergy.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.07.024
Staphylococcus aureus internalisation in mast cells in nasal polyps - Characterisation of interactions and potential mechanisms.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.06.013
Defining the biological responses of IL-6 by the study of a novel IL-6 receptor chain (IL6R) immunodeficiency.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.11.015
T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.11.030
T-cell mitochondrial dysfunction and lymphopenia in DOCK2-deficient patients.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.02.020
Prenatal exposure to traffic-related air pollution, the gestational epigenetic clock and risk of early-life allergic sensitization.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.07.047
Prostaglandin E2-EP2 signaling negatively regulates murine atopic dermatitis-like skin inflammation by suppressing TSLP expression.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.06.036
Antibody response to common human viruses is shaped by genetic factors.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2018.11.039
Lifetime Work Productivity Gains Among Patients with Chronic Rhinosinusitis with Nasal polyps (CRSwNP) Treated with EDS‐FLU: 853
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/J.JACI.2018.12.858
IκBζ is a key player in the anti-psoriatic effects of secukinumab.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.09.029
Evaluation of Eosinophilic Asthma Patients Without Blood Eosinophil (EOS) Response to Intravenous (IV) Reslizumab in a Post‐Hoc Analysis of 52‐Week Placebo‐Controlled Phase 3 Studies: 292
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/J.JACI.2018.12.295
Oral Immunotherapy for Multiple Foods: 779
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/J.JACI.2018.12.784
Efficacy Of 100 Mg SC Mepolizumab For Severe Eosinophilic Asthma (SEA) Across Body Weight: Meta‐Analysis: 306
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/J.JACI.2018.12.309
Epitope Mapping of 2S albumins and Comparison of Ara h 2, Ara h 6 and Ara h 7 from Peanut: 206
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.208
Short Course Of Oral Prednisolone Improves Physician Reported Clinical Scores and Patient Reported Outcomes in Patients with Moderate‐to‐Severe Atopic Dermatitis: 403
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.406
Epicutaneous Immunotherapy (EPIT) for Peanut Allergy in Young Children: 749
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/J.JACI.2018.12.754
Alternative dosing of omalizumab as an adjunct therapy during multiallergen oral immunotherapy in food allergic patients: 744
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.749
Distinct patterns of bacterial vertical transmission from the maternal vaginal tract to infant gut microbiota: 907
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.912
Red Meat Allergy May Develop Independent of Tick Blood Meal Status: 105
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.107
Differential Gene Expression Among Infants at High‐Risk for Peanut Allergy: 253
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.255
Angiopoietin‐2 Is Released Only at Late Phase of Systemic Anaphylaxis in Awake Rats: L13
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.957
3-Methyl-4-nitrophenol triggers nasal allergy by modulating dendritic cell properties.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2018.11.012
Mold and Outdoor Aeroallergen IgE Sensitizations are Associated with Atopic Dermatitis Children who are Hospitalized for Asthma: 319
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.322
Esophageal Eosinophilia is Present in Some Peanut Allergic Patients: 937
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.942
Natural course and factors associated with allergic diseases in the first 2 years: Data from a Developing Asian Countries: 473
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.476
Developing in vitro and in vivo Models to Predict Drug‐Induced Acute Allergic Adverse Reactions: 101
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.103
Factors Associated with Increased Food Allergy‐associated Anxiety in Parents of Food‐allergic Children: 260
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.262
Eosinophilic Esophagitis: Association with atopic diseases and IgE mediated Food Allergy: 421
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.424
Nasal polyps 15-lipoxygenase 1 promotes CCL26/Eotaxin3 expression through ERK activation.
来源期刊：The Journal of allergy and clinical immunologyDOI：10.1016/j.jaci.2019.06.037
A murine desensitization model to interrogate the Factor XII‐mediated contact system in allergic inflammation.: 573
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.576
Oral Tolerance, Skin Inflammation and Physicochemical Characteristics of Wheat‐Derived Products Influence Cutaneous Sensitisation to Wheat: L39
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.983
Identification of reactive oxygen production site in Siglec‐8 induced eosinophil death: 883
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.888
Atopic dermatitis and Environmental Factors Associated with Skin Responses during Infancy: 479
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.482
Efficacy of a quail eggs‐based dietary supplement for allergic rhinitis: 536
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.539
Experience With Immunoglobulin Treatment Among Patients With PIDD in the US: 338
来源期刊：The Journal of Allergy and Clinical ImmunologyDOI：10.1016/j.jaci.2018.12.341
