Expert Opinion on Drug Metabolism & Toxicology (ISSN 1742-5255 [print], 1744-7607 [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles on all aspects of ADME-Tox. Each article is structured to incorporate the author’s own expert opinion on the scope for future development.The Editors welcome:Reviews covering metabolic, pharmacokinetic and toxicological issues relating to specific drugs, drug-drug interactions, drug classes or their use in specific populations; issues relating to enzymes involved in the metabolism, disposition and excretion of drugs; techniques involved in the study of drug metabolism and toxicology; novel technologies for obtaining ADME-Tox data.Drug Evaluations reviewing the clinical, toxicological and pharmacokinetic data on a particular drug.The audience consists of scientists and managers in the pharmaceutical industry, pharmacologists, clinical toxicologists and related professionals.
药物代谢和毒理学专家意见（ISSN 1742-5255 [印刷版]，1744-7607 [电子版]）是一份MEDLINE索引、同行评审的国际期刊，发表了关于ADME-Tox所有方面的综述文章。每篇文章的结构都包含了作者对未来发展范围的专家意见。编辑们欢迎：综述涉及与特定药物、药物相互作用、药物类别或其在特定人群中的使用相关的代谢、药代动力学和毒理学问题;与涉及药物代谢、处置和排泄的酶有关的问题;涉及药物代谢和毒理学研究的技术;获取ADME-Tox数据的新技术。药物评估回顾特定药物的临床、毒理学和药代动力学数据。受众包括制药行业的科学家和管理人员、药理学家、临床毒理学家和相关专业人士。
Hepatotoxicity induced by immune checkpoint inhibitors: a comprehensive review including current and alternative management strategies
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1574744
Chemical activation of estrogen and aryl hydrocarbon receptor signaling pathways and their interaction in toxicology and metabolism
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1569627
Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1604685
Solid lipid matrix mediated nanoarchitectonics for improved oral bioavailability of drugs
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1621289
Pharmacokinetics and pharmacodynamics of new acute treatments for migraine
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1578749
Pharmacogenetics of treatments for pancreatic cancer
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1620731
Pharmacogenetics of alcohol use disorder treatments: an update
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1628218
Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1600670
What “The Cancer Genome Atlas” database tells us about the role of ATP-binding cassette (ABC) proteins in chemoresistance to anticancer drugs
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1631285
Estrogen sulfotransferase in the metabolism of estrogenic drugs and in the pathogenesis of diseases
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1588884
Venetoclax in the treatment of chronic lymphocytic leukemia
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1606211
Platinum-drugs induced peripheral neurotoxicity: clinical course and preclinical evidence
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1622679
Pharmacokinetics and pharmacodynamics of new drugs for pancreatic cancer
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1637417
Opioids and the Risk of Infection: A Critical Appraisal of the Pharmacologic and Clinical Evidence
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1634053
Pharmacokinetic and pharmacodynamic considerations for NMDA-receptor antagonist ketamine in the treatment of chronic neuropathic pain: an update of the most recent literature
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1689958
Molecular basis for class side effects associated with PI3K/AKT/mTOR pathway inhibitors
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1663169
Pharmacokinetics of monoamine oxidase B inhibitors in Parkinson’s disease: current status
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1607292
Pharmacokinetic mechanisms underlying the detoxification effect of Glycyrrhizae Radix et Rhizoma (Gancao): drug metabolizing enzymes, transporters, and beyond
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1563595
Pharmacokinetics and Clinical Pharmacology Considerations of GalNAc3-Conjugated Antisense Oligonucleotides
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1621838
Key insights from therapeutic drug monitoring in Crohn’s disease patients
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1597054
Drug-drug interactions between antiepileptics and cannabinoids
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1605355
Pharmacodynamics, clinical findings and approval status of current and emerging tyrosine-kinase inhibitors for pancreatic neuroendocrine tumors
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1700951
Pharmacokinetic and pharmacodynamic insights from microfluidic intestine-on-a-chip models
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1700950
Pharmacodynamics OF TNF α inhibitors for the treatment of psoriasis
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1681969
Drug–drug interactions in patients receiving hematopoietic stem cell transplantation
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1552256
Monoclonal antibodies in severe asthma: is it worth it?
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1621837
Pharmacokinetic and pharmacodynamic considerations for the clinical efficacy of perampanel in focal onset seizures
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1560420
Drug–drug interactions of a two-drug regimen of dolutegravir and lamivudine for HIV treatment
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1577821
An update on the pharmacokinetic considerations in the treatment of ADHD with long-acting methylphenidate and amphetamine formulations
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1675636
Clinically relevant drug interactions between newer antidepressants and oral anticoagulants
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2020.1700952
Pharmacokinetic drug evaluation of abemaciclib for advanced breast cancer
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1559816
An update on polyphenol disposition via coupled metabolic pathways
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1559815
Old problem, new solutions: biomarker discovery for acetaminophen liver toxicity
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1642323
Enhancement of lung levels of antibiotics by ambroxol and bromhexine
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1578748
Modulation of expression/function of intestinal P-glycoprotein under disease states
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2020.1701653
Is cytochrome oxidase inhibition the primary mechanism in aluminum phosphide poisoning?
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1645833
Pharmacokinetic considerations for current state-of-the-art antidepressants
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1669560
Factors influencing hepatic metabolism of antihypertensive drugs: impact on clinical response
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1558204
Pharmacogenetics of anticoagulants used for stroke prevention in patients with atrial fibrillation
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1623878
Perspectives on adjunctive use of ketamine for analgosedation during extracorporeal membrane oxygenation
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1593963
Tacrolimus in adult hematopoietic stem cell transplantation
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1675635
Comparative and quantitative assessment on statin efficacy and safety: insights into inter-statin and inter-individual variability via dose- and exposure-response relationships
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1681399
The transition of lead and microbial contamination from adulterated opium to the human body
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1588250
In vitro–in vivo correlation of the drug–drug interaction potential of antiretroviral HIV treatment regimens on CYP1A1 substrate riociguat
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1681968
Pharmacogenetics in the clinical analysis laboratory: clinical practice, research, and drug development pipeline
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1658742
Pharmacokinetics and pharmacodynamics of pegylated interferon for the treatment of hepatitis B
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1678584
Pharmacokinetic and pharmacodynamic considerations of cephalosporin use in children
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1678585
Mitochondrial dysfunctions in HIV infection and antiviral drug treatment
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1692814
The effects of fasting on drug metabolism
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2020.1706728
Sunscreen ingredients in plasma: a threat for drug–drug interactions and toxicity among patients living with HIV?
来源期刊：Expert Opinion on Drug Metabolism & ToxicologyDOI：10.1080/17425255.2019.1670164
