The International Journal for Peptide Research & Therapeutics is an international, peer-reviewed journal focusing on issues, research, and integration of knowledge on the latest developments in peptide therapeutics. The Journal brings together in a single source the most exciting work in peptide research, including isolation, structural characterization, synthesis and biological activity of peptides, and thereby aids in the development of unifying concepts from diverse perspectives. The Journal invites substantial contributions in the following thematic areas:-New advances in peptide drug delivery systems.-Application of peptide therapeutics to specific diseases.-New advances in synthetic methods.-The development of new procedures for construction of peptide libraries and methodology for screening of such mixtures.-The use of peptides in the study of enzyme specificity and mechanism, receptor binding and antibody/antigen interactions-Applications of such techniques as chromatography, electrophoresis, NMR and X-ray crystallography, mass spectrometry.
《国际肽研究与治疗学杂志》是一本国际同行评审期刊，专注于肽治疗学最新发展的问题、研究和知识整合。该杂志汇集了肽研究中最令人兴奋的工作，包括肽的分离、结构表征、合成和生物活性，从而有助于从不同的角度发展统一的概念。该杂志邀请在以下主题领域的实质性贡献：-肽药物递送系统的新进展。肽疗法在特定疾病中的应用合成方法的新进展。开发构建肽文库的新程序和筛选此类混合物的方法学。肽在酶的特异性和机理、受体结合和抗体/抗原相互作用研究中的应用-色谱、电泳、NMR和X射线晶体学、质谱等技术的应用。
Expression of Enterocin-P in HEK Platform: Evaluation of Its Cytotoxic Effects on Cancer Cell Lines and Its Potency to Interact with Cell-Surface Glycosaminoglycan by Molecular Modeling
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09956-7
Antimicrobial Peptides (AMPs): Roles, Functions and Mechanism of Action
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09946-9
Purification, Characterization and Antibacterial Properties of Peptide from Marine Ascidian Didemnum sp.
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09829-z
Using Immunoinformatics and Structural Approaches to Design a Novel HHV8 Vaccine
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09839-x
Antitumoral and Antimicrobial Activity of Surfactin Extracted from Bacillus subtilis KLP2015
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09848-w
Health Promoting Effects of Food-Derived Bioactive Peptides: A Review
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09890-8
Creating a Soluble Binder to Endothelin-1 Based on the Natural Ligand Binding Domains of the Endothelin-1 (G-Protein-Coupled) Receptor
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.17863/CAM.20357
Epitope-Based Vaccine Designing of Nocardia asteroides Targeting the Virulence Factor Mce-Family Protein by Immunoinformatics Approach
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09921-4
Intensifying the Anticancer Potential of Cationic Peptide Derived from Serine Threonine Protein Kinase of Teleost by Tagging with Oligo Tryptophan
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09817-3
Epitope Prediction by Novel Immunoinformatics Approach: A State-of-the-art Review
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09918-z
Effects of Hippocampal Microinjection of Irisin, an Exercise-Induced Myokine, on Spatial and Passive Avoidance Learning and Memory in Male Rats
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09842-2
Betaine: A Promising Micronutrient in Diet Intervention for Ameliorating Maternal Blood Biochemical Alterations in Gestational Diabetes Mellitus
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09922-3
In Silico Designing of Peptidomimetics Enhancing Endoribonucleolytic Activities of Acinetobacter MazF Toxin as the Novel Anti-bacterial Candidates
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09908-1
Designing and Modeling of Multi-epitope Proteins for Diagnosis of Toxocara canis Infection
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09940-1
Plant-Derived Bioactive Peptides: A Treatment to Cure Diabetes
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09899-z
Survey the Effect of Insulin on Modulating Feed Intake Via NPY Receptors in 5-Day-Old Chickens
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09852-0
Efficient Fmoc Group Removal Using Diluted 4-Methylpiperidine: An Alternative for a Less-Polluting SPPS-Fmoc/tBu Protocol
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09865-9
MA-[D-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Normalizes Glucose Tolerance and Episodic Memory in a Mouse Model of Type 2 Diabetes Mellitus and Alzheimer’s Disease-Like Cognitive Impairment
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09995-0
Purification, Identification and Functional Analysis of a Novel Immunomodulatory Peptide from Silkworm Pupa Protein
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09832-4
Isolation and Characterization of Conotoxin Protein from Conus inscriptus and Its Potential Anticancer Activity Against Cervical Cancer (HeLa-HPV 16 Associated) Cell Lines
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09907-2
A Precisely Designed Immunotoxin Against VCAM1 Consisting of a Humanized Antibody Variable Domain Fused to Granzyme: An In Silico Approach
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09822-6
Design, Synthesis and Interaction of BRCA1 Peptide Fragments with RAD51(181–200)
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09821-7
MA-[d-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Mirrors the Cognitive Enhancing Action of Leptin in a Mouse Model of Type 1 Diabetes Mellitus and Alzheimer’s Disease-Like Cognitive Impairment
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09929-w
Identification and Antioxidant Activity of a Novel Peptide from Baijiu
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09926-z
Homology Modeling and Molecular Docking Studies of Glutamate Dehydrogenase (GDH) from Cyanobacterium Synechocystis sp. PCC 6803
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09886-4
Contemporary Updates on the Physiology of Glucagon like Peptide-1 and Its Agonist to Treat Type 2 Diabetes Mellitus
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09927-y
Optimization of Anti-CXCL10 Nanobody Expression Using Response Surface Methodology and Evaluation of its Anti-metastatic Effect on Breast Cancer cells
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09941-0
Prediction of the Most Probable B Cell Epitopes from (DnaK) Adhesin of Mycobacterium tuberculosis Using Immunoinformatic tools
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09853-z
Capsaicin but not Genistein Influences Modulation of Lipid Parameters by Obestatin in DIO-C57BL/6 Mice
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09811-9
Comparison of High-Throughput Sequencing for Phage Display Peptide Screening on Two Commercially Available Platforms
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09858-8
Effects of Enzymatic Hydrolysate of Oyster on Erectile Function in Male Hemicastrated Rats
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09989-y
Correction to: Key Role of Disulfide Bridges in the Antimicrobial Activity of Beta-Defensin from Olive Flounder
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09855-x
A Comprehensive Phylogenetic and Bioinformatics Assessment of Hydrophobin Protein (HYPAI) for Drug Delivery: an In Silico Analysis
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09990-5
Bridelia ferruginea Inhibit Rat Heart and Liver Mitochondrial Membrane Permeability Transition Pore Opening Following Myocardial Infarction
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09950-z
Identification of an Immunoglobulin M (IgM) Antibody Against Enolase 1 Protein (ENO1) Derived from HEK-293 Cells in Patients with Kidney Failure
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09919-y
Design, Expression, Purification and Characterization of the Recombinant Immunotoxin 4D5 scFv-TRAIL
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09894-4
Residual Participation and Thermodynamic Stability Due to Molecular Interactions in IL11, IL11Rα and Gp130 from Homo sapiens: An In Silico Outlook for IL11 as a Therapeutic Remedy
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09996-z
Characterization of Changes due to pH Variations in Beta Peptide (25–35) Leading to Alzheimer’s Disease
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09987-0
Intranasal Drug Delivery into Mouse Nasal Mucosa and Brain Utilizing Arginine-Rich Cell-Penetrating Peptide-Mediated Protein Transduction
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09971-8
In Vitro Efficacy of Lipid Conjugated Peptidomimetics Against Mycobacterium smegmatis
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09859-7
Design of a New Peptide Substrate Probe of the Putative Biomarker Legumain with Potential Application in Prostate Cancer Diagnosis Ex Vivo
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09994-1
Systematic Identification and Comparative Analysis of Human Cartilage-Derived Self-peptides Presented Differently by Ankylosing Spondylitis (AS)-Associated HLA-B*27:05 and Non-AS-associated HLA-B*27:09
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09857-9
Purification and Characterization of DT389GCSF Fusion Protein: A Unique Immunotoxin Against the Human Granulocyte-Colony Stimulating Factor Receptor
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09884-6
Hepcidin Peptide Inhibitor as Cardioprotection by Targeting Oxidative Stress and Inflammation in Type 1 Diabetic
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09912-5
Novel Predicted B-Cell Epitopes of PSMA for Development of Prostate Cancer Vaccine
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09954-9
In Silico Design of Epitope-Based Allergy Vaccine Against Bellatella germanica Cockroach Allergens
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09980-7
Antihypertensive and Antioxidant Properties from Whey Protein Hydrolysates Produced by Encapsulated Bacillus subtilis Cells
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-018-9714-9
Salivary Proteomic Analysis of Betel Nut (Areca catechu) Consumers by Mass Spectrometry Revealed Primary Indication of Oral Malignancies
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09909-0
Lebetin Peptides, A New Class of Potent Platelet Aggregation Inhibitors: Chemical Synthesis, Biological Activity and NMR Spectroscopic Study
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09812-8
Ability of Three Kind of Imidazole Dipeptides, Carnosine, Anserine, and Balenine, to Interact with Unsaturated Fatty Acid-Derived Aldehydes and Carbohydrate-Derived Aldehydes
来源期刊：International Journal of Peptide Research and TherapeuticsDOI：10.1007/s10989-019-09975-4
