Experimental Gerontology is a multidisciplinary journal for the publication of work from all areas of biogerontology, with an emphasis on studies focused at the systems level of investigation, such as whole organisms (e.g. invertebrate genetic models), immune, endocrine and cellular systems, as well as whole population studies (e.g. epidemiology).The journal also publishes studies into the behavioural and cognitive consequences of aging, where a clear biological causal link is implicated. Studies aimed at bridging the gap between basic and clinical aspects of gerontology, such as papers on the basic aspects of age-related diseases, are welcomed, as is research orientated toward the modulation of the aging process. Original research manuscripts, special issues, short reports, reviews, mini-reviews, and correspondence are published. Manuscripts on social aspects of aging and reports on clinical studies do not fall within the scope of the journal.
实验老年学》是一本多学科期刊,发表生物老年学各个领域的研究成果,重点关注系统层面的研究,如整个生物体(例如无脊椎动物遗传模型)、免疫、内分泌和细胞系统以及整个种群研究该杂志还发表关于衰老的行为和认知后果的研究,其中涉及明确的生物因果关系。欢迎旨在弥合老年学基础和临床方面之间差距的研究,如关于与年龄有关的疾病的基础方面的论文,以及以调节老化过程为目标的研究。出版原始研究手稿、特刊、短篇报告、评论、小型评论和通信。关于老龄化社会方面的手稿和临床研究报告不属于该杂志的范围。
If my muscle could talk: Myokines as a biomarker of frailty
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110715
Reliability, validity and minimal detectable change of 2-minute walk test, 6-minute walk test and 10-meter walk test in frail older adults with dementia
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.11.001
Towards a unified mechanistic theory of aging
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.05.016
The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.12.004
Brain activity during dual task gait and balance in aging and age-related neurodegenerative conditions: A systematic review
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110756
Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110723
The development of cell senescence
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110742
Physical performance, plasma S-klotho, and all-cause mortality in elderly dialysis patients: A prospective cohort study
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.05.003
Voluntary exercise reverses immune aging induced by oxidative stress in aging mice
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.08.009
Effect of a short multicomponent exercise intervention focused on muscle power in frail and pre frail elderly: A pilot trial
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.11.022
The impact of age and frailty on skeletal muscle autophagy markers and specific strength: A cross-sectional comparison
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110687
Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.12.017
Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110637
Declines in motor transfer following upper extremity task-specific training in older adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.12.012
Movement-evoked pain, physical function, and perceived stress: An observational study of ethnic/racial differences in aging non-Hispanic Blacks and non-Hispanic Whites with knee osteoarthritis
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.05.011
Muscle quality and functionality in older women improve similarly with muscle power training using one or three sets
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110745
Periodized and non-periodized resistance training programs on body composition and physical function of older women
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.03.001
In vitro model of chronological aging of adipocytes: Interrelationships with hypoxia and oxidation
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.03.011
Effects of aerobic fitness on cognitive performance as a function of dual-task demands in older adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.013
Altered gene expression pattern indicates the differential regulation of the immune response system as an important factor in cardiac aging
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.05.001
Monocyte chemoattractant protein-1 (MCP-1) and fibroblast growth factor-21 (FGF-21) as biomarkers of subclinical atherosclerosis in women
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.05.013
Effects of exercise-induced apelin on muscle function and cognitive function in aged mice
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110710
Influence of aging and visual feedback on the stability of hand grip control in elderly adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.024
Moringa oleifera seed extract protects against brain damage in both the acute and delayed stages of ischemic stroke
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.04.014
The effect of short-term methionine restriction on glutathione synthetic capacity and antioxidant responses at the whole tissue and mitochondrial level in the rat liver
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110712
Biomarkers for vascular ageing in aorta tissues and blood samples
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110741
Brain gray matter volume associations with gait speed and related structural covariance networks in cognitively healthy individuals and in patients with mild cognitive impairment: A cross-sectional study
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.05.001
Standardization of the Fried frailty phenotype improves cardiovascular disease risk discrimination
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.021
Effect of all-extremity high-intensity interval training vs. moderate-intensity continuous training on aerobic fitness in middle-aged and older adults with type 2 diabetes: A randomized controlled trial
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.12.013
Effects of moderate mountain hiking and balneotherapy on community-dwelling older people: A randomized controlled trial
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.04.006
Effect of community-based lifestyle interventions on weight loss and cardiometabolic risk factors in obese elderly in China: A randomized controlled trial
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110749
AMPK as a potential pharmacological target for alleviating LPS-induced acute lung injury partly via NLRC4 inflammasome pathway inhibition
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110661
Activity and intracellular localization of senescence-associated β-galactosidase in aging Xenopus oocytes and eggs
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.02.002
Association between body composition and inflammation: A central role of IL-17 and IL-10 in diabetic and hypertensive elderly women
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110734
Neural control of postural sway: Relationship to strength measures in young and elderly adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.005
Association between naturally occurring spine osteoarthritis in geriatric rats and neurogenic inflammation within neurosegmentally linked skeletal muscle
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.002
Changes in motor function and brain cortex mitochondrial active oxygen species production in aged mice
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.012
Isolated pancreatic islet yield and quality is inversely related to organ donor age in rats
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110739
Potassium restriction boosts vacuolar acidity and extends lifespan in yeast
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.02.001
DYRK1A aggravates β cell dysfunction and apoptosis by promoting the phosphorylation and degradation of IRS2
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110659
Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.11.017
Glycemic control and comprehensive metabolic risk factors control in older adults with type 2 diabetes
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110713
Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.11.013
A novel neurocognitive approach for placebo analgesia in neurocognitive disorders
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.01.011
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110753
Role of muscle power output as a mediator between gait variability and gait velocity in hospitalized older adults
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110631
Association between serum carcinoembryonic antigen (CEA) levels and leukoaraiosis in middle-aged and older adults: A cross-sectional study
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110682
Inhibition of TLR9 attenuates skeletal muscle fibrosis in aged sarcopenic mice via the p53/SIRT1 pathway
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.04.008
The activation of immunoglobulin G Fc receptors (FcγRs) with immunoreceptor tyrosine-based activation motifs (ITAMs) promotes cognitive impairment in aged rats with diabetes
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2019.110660
The shape of lives to come
来源期刊:Experimental GerontologyDOI:10.1016/j.exger.2018.05.010