Hepatology International is a peer-reviewed journal featuring articles written by clinicians, clinical researchers and basic scientists is dedicated to research and patient care issues in hepatology. This journal focuses mainly on new and emerging diagnostic and treatment options, protocols and molecular and cellular basis of disease pathogenesis, new technologies, in liver and biliary sciences.Hepatology International publishes original research articles related to clinical care and basic research; review articles; consensus guidelines for diagnosis and treatment; invited editorials, and controversies in contemporary issues. The journal does not publish case reports.
国际肝病是一个同行评审的期刊,其特色是由临床医生、临床研究人员和基础科学家撰写的文章,致力于肝病学的研究和患者护理问题。该杂志主要关注肝胆科学中新的和新兴的诊断和治疗选择、方案以及疾病发病机制的分子和细胞基础、新技术。国际肝病学发表与临床护理和基础研究相关的原创研究文章;评论文章;诊断和治疗的共识指南;应邀发表社论,以及当代问题的争论。该杂志不发表病例报告。
Enhancing Curcumin Oral Bioavailability Through Nanoformulations
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00545-z
Drug–Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00577-5
Clinical and Pharmacokinetic Outcomes of Peak–Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00551-1
Influence of Obesity and Type 2 Diabetes Mellitus on the Pharmacokinetics of Tramadol After Single Oral Dose Administration
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00543-1
High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00591-7
Tacrolimus Variability: A Cause of Donor-Specific Anti-HLA Antibody Formation in Children
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00544-0
Comparison of the Predictive Performance Between Cystatin C and Serum Creatinine by Vancomycin via a Population Pharmacokinetic Models: A Prospective Study in a Chinese Population
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00578-4
Pharmacokinetics of Active Ingredients of Salvia miltiorrhiza and Carthamus tinctorius in Compatibility in Normal and Cerebral Ischemia Rats: A Comparative Study
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00597-1
A Systematic Review of Drug Metabolism Studies of Plants With Anticancer Properties: Approaches Applied and Limitations
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00582-8
Clinical Pharmacokinetics of Vancomycin in Critically Ill Children
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00568-6
In-Vivo Degradation of DNA-Based Therapeutic BC 007 in Humans
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00541-3
Population Pharmacokinetics of Voriconazole in Chinese Patients with Hematopoietic Stem Cell Transplantation
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00556-w
Minimal Physiologically Based Pharmacokinetic Model of Intravenously and Orally Administered Delta-9-Tetrahydrocannabinol in Healthy Volunteers
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00559-7
Inhibitory Effect of Vonoprazan on the Metabolism of [14C]Prasugrel in Human Liver Microsomes
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00554-y
Development and Validation of a New LC–MS/MS Analytical Method for Direct-Acting Antivirals and Its Application in End-Stage Renal Disease Patients
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00584-6
A Critique of Pharmacokinetic Calculators for Drug Dosing Individualization
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00589-1
Further Assessment of the Relay Hepatocyte Assay for Determination of Intrinsic Clearance of Slowly Metabolised Compounds Using Radioactivity Monitoring and LC–MS Methods
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00571-x
Pharmacokinetic Study of a Soft Gelatin Capsule and a Solid-Supersaturatable SMEDDS Tablet of Dutasteride in Beagle Dogs
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00594-4
DPP-4 Inhibitors: Renoprotective Potential and Pharmacokinetics in Type 2 Diabetes Mellitus Patients with Renal Impairment
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00570-y
Investigation of Molecular Properties that Influence the Permeability and Oral Bioavailability of Major β-Boswellic Acids
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00599-z
Correlation of PPM1A Downregulation with CYP3A4 Repression in the Tumor Liver Tissue of Hepatocellular Carcinoma Patients
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00595-3
Retraction Note to: Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00585-5
Influence of MAMA decoction, an Herbal Antimalarial, on the Pharmacokinetics of Amodiaquine in Mice
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00583-7
Vancomycin Pharmacokinetics in Patients with Advanced Cancer Near End of Life
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00564-w
Investigating Stochastic Differential Equations Modelling for Levodopa Infusion in Patients with Parkinson’s Disease
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00580-w
Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone (BAY 94-8862) in Individuals with Mild or Moderate Hepatic Impairment
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00547-x
Comparative Evaluation of Median Versus Youden Index Dichotomization Methods: Exposure–Response Analysis of Mycophenolic Acid and Acyl-Glucuronide Metabolite
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00550-2
Folate–Gold–Bilirubin Nanoconjugate Induces Apoptotic Death in Multidrug-Resistant Oral Carcinoma Cells
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00600-9
Comment on: Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Healthy Chinese Subjects
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00566-8
Effects of UGT1A1 Polymorphism, Gender and Triglyceride on the Pharmacokinetics of Telmisartan in Chinese Patients with Hypertension: A Population Pharmacokinetic Analysis
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00567-7
Cerebrospinal Fluid Drug Concentrations and Clinical Outcome of Patients with Neoplastic Meningitis Treated with Liposomal Cytarabine
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00572-w
Excretion, Metabolism and Cytochrome P450 Inhibition of Methyl 3,4-Dihydroxybenzoate (MDHB): A Potential Candidate to Treat Neurodegenerative Diseases
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00576-6
Effect of Gender on the Pharmacokinetics of ON 123300, A Dual Inhibitor of ARK5 and CDK4/6 for the Treatment of Cancer, in Rats
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00542-2
Pharmacokinetics and Safety of a Diclofenac Sodium 75 mg/1 mL Solution (Akis®/Dicloin®) Administered as a Single Intravenous Bolus Injection in Healthy Men and Women
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00558-8
Glucose-Responsive Microspheres as a Smart Drug Delivery System for Controlled Release of Insulin
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00588-2
Current Understanding of the Equivalence Evaluations for In Vitro Tests on Generic Dry Powder Inhaler Drug Products in Japan
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00561-z
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Atacicept in a Randomized Trial in Healthy Caucasian and Japanese Subjects
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00575-7
Fluctuations in Pharmacokinetics Profiles of Monoclonal Antibodies
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00548-w
Bioequivalence Evaluation of Three Pediatric Oral Formulations of Bilastine in Healthy Subjects: Results from a Randomized, Open Label, Crossover Study
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00596-2
Dose Escalation Study to Assess the Pharmacokinetic Parameters of a Nano-amorphous Oral Sirolimus Formulation in Healthy Volunteers
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00562-y
Effect of Fluconazole and Itraconazole on the Pharmacokinetics of Erdafitinib in Healthy Adults: A Randomized, Open-Label, Drug–Drug Interaction Study
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00581-9
Effect of Multiple-Dose Aprocitentan Administration on the Pharmacokinetics of Midazolam in Healthy Male Subjects
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00590-8
In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00557-9
Author’s Reply to: “Comment on: Pharmacokinetics and Safety of Recombinant Human Interleukin-1 Receptor Antagonist GR007 in Chinese Healthy Subjects”
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00574-8
Predictability of Capillary Blood Spot Toward Venous Whole Blood Sampling for Therapeutic Drug Monitoring of Tacrolimus in Solid Organ Transplant Recipients
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00553-z
Glucuronidation of d-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00549-9
Evaluation of Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Glomerular Filtration Rate and Amikacin Clearance During Early Rat Endotoxemia: Comparison with Traditional Endogenous and Exogenous Biomarkers
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00579-3
In Vitro Study of the Enzymatic and Nonenzymatic Conjugation of Treosulfan with Glutathione
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00555-x
Acknowledgement to Referees
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00586-4
Is Cystatin C Good Enough as a Biomarker for Vancomycin Dosing: A Pharmacokinetic Perspective
来源期刊:European Journal of Drug Metabolism and PharmacokineticsDOI:10.1007/s13318-019-00587-3