Epigenetics publishes peer-reviewed original research and review articles that provide an unprecedented forum where epigenetic mechanisms and their role in diverse biological processes can be revealed, shared, and discussed. Epigenetics research studies heritable changes in gene expression caused by mechanisms others than the modification of the DNA sequence. Epigenetics therefore plays critical roles in a variety of biological systems, diseases, and disciplines. Topics of interest include (but are not limited to):DNA methylationNucleosome positioning and modificationGene silencingImprintingNuclear reprogrammingChromatin remodelingNon-coding RNANon-histone chromosomal elementsDosage compensationNuclear organizationEpigenetic therapy and diagnosticsNutrition and environmental epigeneticsCancer epigeneticsNeuroepigenetics
表观遗传学出版同行评审的原创研究和评论文章,提供了一个前所未有的论坛,表观遗传机制及其在不同生物过程中的作用可以揭示,分享和讨论。表观遗传学研究由DNA序列修饰以外的机制引起的基因表达的可遗传变化。因此,表观遗传学在各种生物系统、疾病和学科中发挥着重要作用。感兴趣的主题包括(但不限于):DNA甲基化核小体定位和修饰基因沉默印记核重编程染色质重塑非编码RNA非组蛋白染色体元件剂量补偿核组织表观遗传治疗和诊断营养和环境表观遗传学癌症表观遗传学神经表观遗传学
DNA methylation dynamics during epigenetic reprogramming of medaka embryo
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1605816
DNA methylation changes associated with Parkinson’s disease progression: outcomes from the first longitudinal genome-wide methylation analysis in blood
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1588682
LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure
来源期刊:EpigeneticsDOI:10.1080/15592294.2018.1561117
Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1656158
Regulation of OCT2 transcriptional repression by histone acetylation in renal cell carcinoma
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1615354
DNA methylation markers in obesity, metabolic syndrome, and weight loss
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1595297
Developmental changes and sex differences in DNA methylation and demethylation in hypothalamic regions of the mouse brain
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1649528
Circulating levels of inflammatory markers and DNA methylation, an analysis of repeated samples from a population based cohort
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1603962
Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1585177
An inverse interaction between HOXA11 and HOXA11-AS is associated with cisplatin resistance in lung adenocarcinoma
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1625673
Epigenomic profiling of newborns with isolated orofacial clefts reveals widespread DNA methylation changes and implicates metastable epiallele regions in disease risk
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1581591
Novel DNA methylation sites associated with cigarette smoking among African Americans
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1588683
EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1573066
Epigenetic activation of POTE genes in ovarian cancer
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1581590
The dynamics of DNA methylation during epigenetic reprogramming of primordial germ cells in medaka (Oryzias latipes)
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1695341
Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1580112
DNA methylation changes following DNA damage in prostate cancer cells
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1629231
DEMETER plays a role in DNA demethylation and disease response in somatic tissues of Arabidopsis
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1631113
Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1582217
Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1600390
Superovulation alters global DNA methylation in early mouse embryo development
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1615353
Don’t brush off buccal data heterogeneity
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1581592
Global modulation in DNA epigenetics during pro-inflammatory macrophage activation
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1638700
Decreased global DNA hydroxymethylation in neural tube defects: Association with polycyclic aromatic hydrocarbons
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1629233
Comparison of Illumina 450K and EPIC arrays in placental DNA methylation
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1634975
Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1629234
Cell lineage-specific genome-wide DNA methylation analysis of patients with paediatric-onset systemic lupus erythematosus
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1585176
Locus-specific DNA methylation prediction in cord blood and placenta
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1588685
MBD-seq - realities of a misunderstood method for high-quality methylome-wide association studies
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1695339
Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1640547
Strategy for the analysis of tissue-specific methylation changes without physical isolation
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1565589
Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1603963
Altered expression of epigenetic regulators and imprinted genes in human placenta and fetal tissues from second trimester spontaneous pregnancy losses
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1634988
Persistent epigenetic changes in adult daughters of older mothers
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1595299
The rs17084733 variant in the KIT 3’ UTR disrupts a miR-221/222 binding site in gastrointestinal stromal tumour: a sponge-like mechanism conferring disease susceptibility
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1595997
Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1626651
Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1669375
X-ray irradiation induces subtle changes in the genome-wide distribution of DNA hydroxymethylation with opposing trends in genic and intergenic regions
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1568807
Genome-wide characterization of cytosine-specific 5-hydroxymethylation in normal breast tissue
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1695332
Stromal-associated cytokines bias the interplay between gene expression and DNA methylation in human breast cancers
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1699893
Polychlorinated biphenyl exposure and DNA methylation in the Anniston Community Health Survey
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1666654
Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial–mesenchymal transition and subcellular re-localization of Beta-Catenin
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1656154
Age-related DNA hydroxymethylation is enriched for gene expression and immune system processes in human peripheral blood
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1666651
Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1666652
A method for identifying allele-specific hydroxymethylation
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1664228
Lysine methyltransferase SETD6 modifies histones on a glycine-lysine motif
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1649529
PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1676597
Epigenome-wide effects of vitamin D on asthma bronchial epithelial cells
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1622993
aFARP-ChIP-seq, a convenient and reliable method for genome profiling in as few as 100 cells with a capability for multiplexing ChIP-seq
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1621139
Correlation of Infinium HumanMethylation450K and MethylationEPIC BeadChip arrays in cartilage
来源期刊:EpigeneticsDOI:10.1080/15592294.2019.1700003