Current Problems in Cancer seeks to promote and disseminate innovative, transformative, and impactful data on patient-oriented cancer research and clinical care. Specifically, the journal's scope is focused on reporting the results of well-designed cancer studies that influence/alter practice or identify new directions in clinical cancer research. These studies can include novel therapeutic approaches, new strategies for early diagnosis, cancer clinical trials, and supportive care, among others. Papers that focus solely on laboratory-based or basic science research are discouraged. The journal's format also allows, on occasion, for a multi-faceted overview of a single topic via a curated selection of review articles, while also offering articles that present dynamic material that influences the oncology field.
《当前癌症问题》旨在促进和传播以患者为导向的癌症研究和临床护理的创新、变革和有影响力的数据。具体而言，该杂志的范围集中在报告精心设计的癌症研究的结果，这些研究影响/改变了临床癌症研究的实践或确定了新的方向。这些研究可以包括新的治疗方法、早期诊断的新策略、癌症临床试验和支持性护理等。不鼓励只关注实验室或基础科学研究的论文。期刊的格式有时还允许通过精选的综述文章对单个主题进行多方面的概述，同时还提供影响肿瘤学领域的动态材料。
Metformin in breast cancer: preclinical and clinical evidence.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.06.003
Clinical evaluation of carcinoembryonic and carbohydrate antigens as cancer biomarkers to monitor palliative chemotherapy in advanced stage gastric cancer.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.08.003
The possible role of insulin-like growth factor-1 in osteosarcoma.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.08.008
A six-microRNA signature predicts survival of patients with uterine corpus endometrial carcinoma.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.02.002
Clinicopathologic significance of LAIR-1 expression in hepatocellular carcinoma.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.04.005
Comparison of CA125, HE4, and ROMA index for ovarian cancer diagnosis.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.06.001
Do estrogen, progesterone, P53 and Ki67 receptor ratios determined from curettage materials in endometrioid-type endometrial carcinoma predict lymph node metastasis?
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.07.003
Treatment outcomes and incidence of brain metastases in pulmonary large cell neuroendocrine carcinoma.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.05.006
Outcome comparisons of high-grade glioma resection with or without fluorescein sodium-guidance.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.07.007
Future directions in soft tissue sarcoma treatment.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.06.004
Risk and survival of chronic myeloid leukemia after breast cancer: A population-based study.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.08.005
Diagnostic accuracy of CA125 and HE4 in ovarian carcinoma patients and the effect of confounders on their serum levels.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.12.004
Causal effect of obesity on gynecologic malignancies.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.07.011
Polymorphism rs3819102 in thymidylate synthase and environmental factors: effects on lung cancer in Chinese population.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.07.005
Pericardial effusion due to pembrolizumab-induced immunotoxicity: A case report and literature review.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.01.001
Portal vein stent for symptomatic malignant portal vein stenosis: A single-center experience.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.04.002
Circulating tumor DNA/circulating tumor cells and the applicability in different causes induced hepatocellular carcinoma.
来源期刊：Current problems in cancerDOI：10.1016/J.CURRPROBLCANCER.2019.100516
Brigatinib: New-generation ALK inhibitor for nonsmall cell lung cancer.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.03.005
Young-age onset colorectal cancer in Brazil: Analysis of incidence, clinical features, and outcomes in a tertiary cancer center.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.01.009
NAT10 upregulation indicates a poor prognosis in acute myeloid leukemia.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.06.006
Prognostic significance of the skeletal muscle index and an inflammation biomarker in patients with breast cancer who underwent postoperative adjuvant radiotherapy.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100513
Hepatosteatosis may predict late recurrence of breast cancer: A single-center observational study.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.01.002
Pseudoprogression on treatment with immune-checkpoint inhibitors in patients with gastrointestinal malignancies: Case series and short literature review.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.01.008
Vitamin D deficiency in cancer patients and predictors for screening (D-ONC study).
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.12.008
Contemporary management of metastatic soft tissue sarcoma.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.06.005
Changes in body composition during neoadjuvant therapy can affect prognosis in rectal cancer patients: An exploratory study.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100510
Second primary malignancy in diffuse large B-cell lymphoma patients: A SEER database analysis.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100502
Burnout Among oncologists in the Republic of Korea: A nationwide survey.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100535
The role of histopathologic testing on apocrine carcinoma of the breast.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100501
Association of lymphadenectomy and survival in epithelial ovarian cancer.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.08.002
Risk factors of mortality in the patients with hepatocellular carcinoma: A multicenter study in Indonesia.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.05.003
The prognostic role of peritoneal cytology in stage IA endometrial endometrioid carcinomas.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100514
Insurance status is related to overall survival in patients with small intestine adenocarcinoma: A population-based study.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100505
The diagnostic and prognostic roles of serum irisin in bladder cancer.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100529
Alterations in XRCC1 gene profile in pathogenesis of oral cavity cancer: A population-based study from Kamrup Urban District of Assam, India.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.03.003
What is the real prognostic value of close margins in oral oncology?
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100500
Involved-field irradiation for elderly bladder cancer patients.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.07.009
Prevalence of bone pain decreases as lymph node stage increases in nonsmall cell lung cancer patients.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.08.006
Axillary web syndrome: Incidence, pathogenesis, and management.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.02.002
Breast cancer after multiple myeloma treatment.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.01.004
Atypical PRES with diffusion restriction or neurotoxicity- ? part of same spectrum-after oxaliplatin (FOLFOX-4 regimen) for colonic cancer.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.04.004
Hopelessness is associated with poor sleep quality after breast cancer surgery among Tunisian women.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100504
Hepatoid adenocarcinoma of the renal pelvis in a 59-year-old male with nephrolithiasis: Case report and review of the literature.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2018.12.007
Uterine sarcomas.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.06.001
Efficacy of zoledronic acid for prevention of bone loss in early-stage breast cancer patients receiving adjuvant therapy: A meta-analysis of 13 randomized controlled trials.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100507
A phase II multicenter randomized controlled trial to compare standard chemoradiation with or without recombinant human endostatin injection (Endostar) therapy for the treatment of locally advanced nasopharyngeal carcinoma: Long-term outcomes update.
来源期刊：Current problems in cancerDOI：10.1016/J.CURRPROBLCANCER.2019.06.007
Factors associated with mortality from lung cancer in India.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.100512
Effect of clinicopathologic features on survival of patients with thymic carcinomas and thymic neuroendocrine tumors: A population-based analysis.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.03.004
Metastatic gastric adenocarcinoma of the tongue with initial symptoms of glossodynia.
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.05.004
Radiological and histological findings of an asymptomatic ever-increasing neoplasm: The small bowel neuroendocrine tumor (NET).
来源期刊：Current problems in cancerDOI：10.1016/j.currproblcancer.2019.07.001
