Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry.The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.
《高级合成与催化》（ASC）是有机、有机金属和应用化学领域的领先期刊。ASC的高影响力可归因于该期刊的独特关注点，它发表了来自学术和工业实验室的关于高效、实用和环境友好的有机合成的令人兴奋的新结果。均相、非均相、有机和酶催化是实现绿色合成的关键技术，而合成设计、反应技术、流动化学和连续加工、多相催化、绿色溶剂、催化剂固定化和回收、分离科学和工艺开发也为实现同一目标做出了重大贡献。目标和范围可在《作者须知》或每期目录的第一页上找到。
Progress in Difluoroalkylation of Organic Substrates by Visible Light Photoredox Catalysis
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201801121
Enzyme‐Catalysed Synthesis of Secondary and Tertiary Amides
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900694
Catalytic Hydroboration of Organic Nitriles Promoted by Aluminum Complex
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801252
De novo design of organic photocatalysts: bithiophene derivatives for the visible-light induced C−H functionalization of heteroarenes
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801571
Non‐Oxidative Enzymatic (De)Carboxylation of (Hetero)Aromatics and Acrylic Acid Derivatives
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900275
Random Mutagenesis-Driven Improvement of Carboxylate Reductase Activity Using an Amino Benzamidoxime-Mediated High-Throughput Assay
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900155
Influence of Mesoporous Silica Properties on Cyclic Carbonate Synthesis Catalysed by Supported Aluminium(Salen) Complexes
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801229
Structure‐Guided Evolution of Aryl Alcohol Oxidase from Pleurotus eryngii for the Selective Oxidation of Secondary Benzyl Alcohols
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900134
N‐Heterocyclic Carbene Catalyzed Asymmetric Synthesis of Pentacyclic Spirooxindoles via [3+3] Annulations of Isatin‐Derived Enals and Cyclic N‐Sulfonyl Ketimines
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900065
A Bipyridine‐Palladium Derivative as General Pre‐Catalyst for Cross‐Coupling Reactions in Deep Eutectic Solvents
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900472
Functionalization of Enzymatically Synthesized Rigid Poly(itaconate)s via Post‐Polymerization Aza‐Michael Addition of Primary Amines
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900055
Substrate‐Independent High‐Throughput Assay for the Quantification of Aldehydes
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900154
Brønsted Acid‐Catalyzed Direct C(sp2)−H Heteroarylation Enabling the Synthesis of Structurally Diverse Biaryl Derivatives
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801226
Efficient Aerobic Oxidation of trans‐2‐Hexen‐1‐ol using the Aryl Alcohol Oxidase from Pleurotus eryngii
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801312
Stimulus‐Responsive Regulation of Enzyme Activity for One‐Step and Multi‐Step Syntheses
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900169
Biocatalytic Enantioselective Hydroaminations for Production of N-Cycloalkyl-Substituted L-Aspartic Acids Using Two C-N Lyases
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801569
B(C6F5)3‐Catalyzed Deoxygenative Reduction of Amides to Amines with Ammonia Borane
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801447
Bubble Column Enables Higher Reaction Rate for Deracemization of (R,S)‐1‐Phenylethanol with Coupled Alcohol Dehydrogenase/NADH Oxidase System
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900213
in situ Formation of RSCl/ArSeCl and Their Oxidative Coupling with Enaminone Derivatives Under Transition‐metal Free Conditions
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900940
Potassium tert‐Butoxide‐Promoted Acceptorless Dehydrogenation of N‐Heterocycles
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900499
Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts.
来源期刊：Advanced synthesis & catalysisDOI：10.1002/ADSC.201800987
Old Concepts, New Application – Additive‐Free Hydrogenation of Nitriles Catalyzed by an Air Stable Alkyl Mn(I) Complex
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201901040
Efficient Non‐Catalytic Carboxylation of Diamines to Cyclic Ureas Using 2‐Pyrrolidone as a Solvent and a Promoter
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201800945
Clean Enzymatic Oxidation of 12α-Hydroxysteroids to 12-Oxo-Derivatives Catalyzed by Hydroxysteroid Dehydrogenase
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900144
Ru‐Catalyzed Deoxygenative Transfer Hydrogenation of Amides to Amines with Formic Acid/Triethylamine
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900406
An Enzymatic 2‐Step Cofactor and Co‐Product Recycling Cascade towards a Chiral 1,2‐Diol. Part I: Cascade Design
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900187
Synthesis of Cyclic N‐Hydroxylated Ureas and Oxazolidinone Oximes Enabled by Chemoselective Iodine(III)‐Mediated Radical or Cationic Cyclizations of Unsaturated N‐Alkoxyureas
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201901135
Toward Automated Enzymatic Glycan Synthesis in a Compartmented Flow Microreactor System
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900709
Heterogeneous Nickel‐Catalyzed Cross‐Coupling between Aryl Chlorides and Alkyllithiums Using a Polystyrene‐Cross‐Linking Bisphosphine Ligand
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801713
Chemoenzymatic Synthesis of Sialic Acid Derivatives Using Immobilized N‐Acetylneuraminate Lyase in a Continuous Flow Reactor
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900146
Direct Photoassisted α‐Trifluoromethylation of Aromatic Ketones with Trifluoroacetic Anhydride (TFAA)
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801305
Iridium‐Catalyzed Asymmetric Hydrogenation of N‐Alkyl α‐Aryl Furan‐Containing Imines: an Efficient Route to Unnatural N‐Alkyl Arylalanines and Related Derivatives.
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801143
Enantioselective Synthesis of d‐ and l‐α‐Amino Acids by Enzymatic Transamination Using Glutamine as Smart Amine Donor
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801278
Biocatalytic Enantioselective Oxidation of Sec‐Allylic Alcohols with Flavin‐Dependent Oxidases
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900921
Cyclisation Reactions Involving Alkyl Enol Ethers
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900478
Selective hydrodefluorination of hexafluoropropene to industrially relevant hydrofluoroolefins
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900234
C-Glycosyl Styrene Type Compounds by Pd-Catalyzed Cross-Coupling Reactions of Anhydro-Aldose Tosylhydrazones with Benzyl Bromides
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801059
An Organocatalytic Two-atom Ring Expansion Approach to Optically Active Glutarimides
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900159
Conformational Control of Tetrahydropyran-based Hybrid Dipeptide Catalysts Improves Activity and Stereoselectivity
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900247
Studies on the Laccase-Catalyzed Oxidation of 4-Hydroxy-Chalcones
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900190
Engineering the Active Site of an (S)-Selective Amine Transaminase for Acceptance of Doubly Bulky Primary Amines
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201901252
CH‐π Interactions Promote the Conversion of Hydroxypyruvate in a Class II Pyruvate Aldolase
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900205
Chemoselectivity Switching in the Rhodium‐Catalyzed Reactions of 4‐Substituted‐1‐sulfonyl‐1,2,3‐triazoles with Allenols: Noticeable Differences between 4‐Acyl‐ and 4‐Aryl‐Triazoles
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801424
Exploration of Aldol Reactions Catalyzed by Stereoselective Pyruvate Aldolases with 2‐Oxobutyric Acid as Nucleophile
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900128
Mild Iridium‐Catalysed Isomerization of Epoxides. Computational Insights and Application to the Synthesis of β‐Alkyl Amines
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900372
cis‐Dihydroxylation of Tricyclic Arenes and Heteroarenes Catalyzed by Toluene Dioxygenase: A Molecular Docking Study and Experimental Validation
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900147
Transition‐Metal‐Free Electrophilic Fluoroalkanesulfinylation of Electron‐Rich (Het)Arenes with Fluoroalkyl Heteroaryl Sulfones via C(Het)‐S and S=O bond cleavage
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900959
Substrate‐Controlled Divergent Synthesis of Enaminones and Pyrroles from Indolizines and Nitroso Compounds
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/adsc.201900837
Atroposelective Synthesis of PINAP via Dynamic Kinetic Asymmetric Transformation
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201801248
Exploring the Biocatalytic Potential of a Self-Sufficient Cytochr ome P450 from Thermothelomyces thermophila
来源期刊：Advanced Synthesis & CatalysisDOI：10.1002/ADSC.201900076
