Cancer Research is the most frequently cited cancer journal in the world. The journal publishes original studies, reviews, and opinion pieces offering significance and broad impact to a diverse audience spanning basic, preclinical, clinical, prevention and epidemiological research. Cancer Research seeks manuscripts that offer pathobiological and translational impact to inform the personal, clinical, and societal problems posed by cancer. The main scope of the Journal is captured in its primary subsections, which focus on molecular and cellular pathobiology, tumor and stem cell biology, therapeutics and targets, microenvironment and immunology, prevention and epidemiology, and integrated systems and technology.
《癌症研究》是世界上被引用频率最高的癌症杂志。该杂志发表原创研究、评论和观点文章，为基础、临床前、临床、预防和流行病学研究等不同受众提供重要性和广泛影响。癌症研究寻求手稿，提供病理生物学和翻译的影响，以告知个人，临床和社会问题所造成的癌症。该杂志的主要内容包括分子和细胞病理生物学、肿瘤和干细胞生物学、治疗学和靶点、微环境和免疫学、预防和流行病学以及综合系统和技术。
CXCR7 reactivates ERK signaling to promote resistance to EGFR kinase inhibitors in NSCLC.
来源期刊：Cancer researchDOI：10.1158/0008-5472.CAN-19-0024
Inactivation of the AMPK-GATA3-ECHS1 Pathway induces Fatty Acid Synthesis that Promotes Clear Cell Renal Cell Carcinoma Growth.
来源期刊：Cancer researchDOI：10.1158/0008-5472.CAN-19-1023
Topological Tumor Graphs: a graph-based spatial model to infer stromal recruitment for immunosuppression in melanoma histology.
来源期刊：Cancer researchDOI：10.1158/0008-5472.CAN-19-2268
Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis.
来源期刊：Cancer researchDOI：10.1158/0008-5472.CAN-19-1145
Abstract 4077: ATOR-1144 is a tumor-directed CTLA-4 x GITR bispecific antibody that acts by depleting Tregs and activating effector T cells and NK cells
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4077
Abstract 4446: Assessment of tissue composition with digital pathology in colorectal cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4446
Abstract 878: IGFBP2 is required to activate EGFR-DNA-PKcs pathway to protect esophageal adenocarcinoma cells from acidic bile salts-induced DNA damage
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-878
Abstract 3387: Comprehensive detection and analysis of mutant-SF3B1splice pattern
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-3387
Abstract 5072: Targeting the mTOR/TORC Pathway for the prevention of er-negative and triple-negative breast cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-5072
Determination of Thymidine Kinase 1 (TK1) Level as a Risk Warning Biomarker to Improve Early Detection of Breast Cancer
来源期刊：Cancer ResearchDOI：10.11648/J.CRJ.20190704.17
Abstract 4887: RecurrentNRG1rearrangements in Caucasian pulmonary mucinous adenocarcinoma: results from an Italian multi-center cohort
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4887
Abstract 1343: SNPs in the NFKB alternative pathway genes CD40, BAFFR and LTβR in CRC
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-1343
Abstract 2780: IL13RA2 is differentially regulated in papillary thyroid carcinoma versus follicular thyroid carcinoma
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2780
Abstract 4823: Elimination of invasive pancreatic cancer cells by p53-activating oncolytic virotherapy as novel precision medicine
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4823
Abstract 964: The association of meat intake, meat cooking methods, and meat-derived mutagen exposure with the risk of sessile serrated polyps
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-964
Abstract 3325: EGFR mutation and protein expression analysis in sinonasal inverted papilloma and squamous cell carcinoma
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-3325
Abstract 4041: Coupling neoantigen specific T cell clonotypes and their molecular phenotypes at the single cell level in resectable anti-PD-1 treated NSCLC
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4041
Abstract P4-06-22: Transcription factor T-bet and PD-L1 expression in tumor microenvironment of triple-negative breast cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-P4-06-22
Abstract 877: Novel role of truncated HMGA2 in regulating reactive oxygen species in prostate cancer cells
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-877
Abstract P3-05-03: Identification of epigenetically silenced breast cancer driver genes
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-P3-05-03
Abstract 2172: Quantification of ERK activity in cancer cell lysates and tumor extract using differential sensing methods
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2172
Abstract 2264: Synergistic combination of oncolytic virotherapy and immunotherapy for glioma
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2264
Abstract 3795: Antibiotics induce mitochondrial dysfunction, DNA damage and aerobic glycolysis of human mammary epithelia and fibroblast
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-3795
Abstract 1299: Potential antitumor effects of a Golgi disrupting agent, M-COPA,viatargeting cell-extracellular matrix interaction under the spheroid culture conditions
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-1299
Abstract P1-10-01: Defining the spectrum of germline variants among African American patients with triple negative breast cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-P1-10-01
Abstract 2583: DNA-linked gold nanoprobe assay: An efficient technology for direct and high-sensitive quantification of serum microRNAs in prostate cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2583
Abstract 2983: LpMab-23: an anti-podoplanin cancer-specific antibody for a prognostic marker of oral cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2983
Abstract OT2-09-01: Pilot study of denosumab in BRCA1/2 mutation carriers scheduling for risk-reducing salpingo-oophorectomy
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-OT2-09-01
Abstract 707: Emerging role of mitochondrial pathway in crosstalk between ferroptosis and apoptosis
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-707
Abstract 5053: Epstein-Barr virus prevalence in classical Hodgkin lymphoma tumors is explained by histologic subtype, not race/ethnicity in a multiethnic US population
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-5053
Abstract P4-09-04: Associations between clinical factors in v7.02 of the Tyrer-Cuzick model and a SNP-based residual risk score
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-P4-09-04
Abstract 889: Biochemical and histopathological evaluation of Al2O3nanomaterials in kidney of Wistar rats
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-889
Abstract 4376: Targeting glutamine metabolism disables Warburg physiology by inhibiting proximal glycolysis and Krebs cycle rewiring
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-4376
Abstract 2438: Rapid fluorescence based assessment of RNA integrity quality using machine learning
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2438
Abstract CT140: Circulating tumor cells as a tool to guide first line therapy in metastatic breast cancer: subgroup analyses of the STIC CTC Phase III utility trial
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-CT140
Abstract 1126: Association of CXCR4 expression with lymph node metastasis in distal cholangiocarcinoma
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-1126
Abstract 4874: Incidental gallbladder cancer: Best step forward
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4874
Abstract LB-213: ecTMB: A robust method to estimate and classify tumor mutational burden
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-LB-213
Abstract 3908: The combination of NVP-BEZ235 & endostatin exerts synergistic anticancer activity against triple-negative breast cancer in vitro and in vivo
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-3908
Abstract 473: Higher levels of genomic complexity correlates with an advanced plasma cell differentiation status in newly diagnosed multiple myeloma patients
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-473
Abstract 4845: HERA-CD27L, a true CD27 agonist, is a hexavalent CD27 ligand that enhances T cell activation and induces potent anti-tumor immunity
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4845
Abstract 1593: Genetic interactions in lung cancer using machine-learning approaches in genome-wide association studies
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-1593
Abstract 1672: Clinical validation of a genomics-based classifier to predict tissue of origin from targeted tumor sequencing
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-1672
Abstract 4448: Machine-learning assisted histopathology (HistoMAP) links nuclear membrane instability to disease progression in prostate cancer
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4448
Abstract 2852: PKM2 phosphorylates and stabilises Matrin 3 which promotes FOXC2-mediated tumorigenesis
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2852
Abstract 2453: A new deconvolution algorithm for accurate assessing immune and stromal cell populations in mouse transcriptomic data
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-2453
Abstract 4274: RNA methylation regulates osteosarcoma growth and progression via autophagy
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-4274
Abstract 959: Proteomic and genetic interaction mapping of the Ras pathway reveals new effectors and vulnerabilities
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-959
Abstract LB-176: Transcriptome-wide association study revealed a novel gene associated with persistent hepatitis B virus infection among Chinese
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.AM2019-LB-176
Abstract CT045: Hyleukin-7, a long-acting interleukin-7, increased absolute lymphocyte counts after subcutaneous and intramuscular administration in healthy subjects
来源期刊：Cancer ResearchDOI：10.1158/1538-7445.SABCS18-CT045
