Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from, but not limited to, work using cell culture techniques.The journal focuses on novel cancer studies reporting data from biological experiments performed on cells grown in vitro, in two- or three-dimensional systems, and/or in vivo (animal experiments). These types of experiments have provided crucial data in many fields, from cell proliferation and transformation, to epithelial-mesenchymal interaction, to apoptosis, and host immune response to tumors.Cancer Cell International also considers articles that focus on novel technologies or novel pathways in molecular analysis and on epidemiological studies that may affect patient care, as well as articles reporting translational cancer research studies where in vitro discoveries are bridged to the clinic. As such, the journal is interested in laboratory and animal studies reporting on novel biomarkers of tumor progression and response to therapy and on their applicability to human cancers.
癌症细胞国际发表癌症细胞生物学各方面的文章，主要来源于，但不限于，使用细胞培养技术的工作。该杂志专注于新的癌症研究，报告来自体外，二维或三维系统中生长的细胞，和/或体内（动物实验）的生物实验数据。这些类型的实验为许多领域提供了关键数据，从细胞增殖和转化，到上皮-间充质相互作用，到细胞凋亡，以及宿主对肿瘤的免疫反应。癌细胞国际还考虑关注分子分析中的新技术或新途径以及可能影响患者护理的流行病学研究的文章，以及报道转化癌症研究的文章，其中将体外发现桥接到临床。因此，该杂志感兴趣的是实验室和动物研究，报告肿瘤进展和治疗反应的新生物标志物及其对人类癌症的适用性。
The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0733-1
hsa_circ_0081143 promotes cisplatin resistance in gastric cancer by targeting miR-646/CDK6 pathway
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0737-x
MicroRNA-144 inhibits cell proliferation, migration and invasion in human hepatocellular carcinoma by targeting CCNB1
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0729-x
The lncRNA TDRG1 promotes cell proliferation, migration and invasion by targeting miR-326 to regulate MAPK1 expression in cervical cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0872-4
The role of MDM2 amplification and overexpression in therapeutic resistance of malignant tumors
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0937-4
CRISPR–Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0726-0
Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0771-8
Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0986-8
Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0725-1
The role of photodynamic therapy on multidrug resistant breast cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0815-0
Circulating tumor cells in precision oncology: clinical applications in liquid biopsy and 3D organoid model
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1067-8
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial–mesenchymal transition
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0730-4
Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0852-8
Cancer-associated fibroblast-derived exosomal microRNA-98-5p promotes cisplatin resistance in ovarian cancer by targeting CDKN1A
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1051-3
Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0861-7
Effects of pericytes and colon cancer stem cells in the tumor microenvironment
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0888-9
Genetic polymorphisms of estrogen receptor genes are associated with breast cancer susceptibility in Chinese women
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0727-z
p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0910-2
The E2F3/miR-125a/DKK3 regulatory axis promotes the development and progression of gastric cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0930-y
Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0799-9
SOX2 interferes with the function of CDX2 in bile acid-induced gastric intestinal metaplasia
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0739-8
Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1061-1
Cell death-related molecules and biomarkers for renal cell carcinoma targeted therapy
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0939-2
Long non-coding RNA UCA1 promotes breast cancer by upregulating PTP1B expression via inhibiting miR-206
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0958-z
Peripheral memory and naïve T cells in non-small cell lung cancer patients with lung metastases undergoing stereotactic body radiotherapy: predictors of early tumor response
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0839-5
Identifying a ten-microRNA signature as a superior prognosis biomarker in colon adenocarcinoma
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1074-9
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0869-z
Effect of hyperoside on cervical cancer cells and transcriptome analysis of differentially expressed genes
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0953-4
Predictive and prognostic value of ZEB1 protein expression in breast cancer patients with neoadjuvant chemotherapy
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0793-2
Prognostic impact of platelet-to-lymphocyte ratio on diffuse large B-cell lymphoma: a meta-analysis
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0962-3
Roles of β-catenin, TCF-4, and survivin in nasopharyngeal carcinoma: correlation with clinicopathological features and prognostic significance
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0764-7
Silencing expression of PHF14 in glioblastoma promotes apoptosis, mitigates proliferation and invasiveness via Wnt signal pathway
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1040-6
Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0849-3
Prognostic value of YKL-40 in solid tumors: a meta-analysis of 41 cohort studies
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0983-y
KLF8 overexpression promotes the growth of human lung cancer cells by promoting the expression of JMJD2A
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0970-3
Casticin inhibits nasopharyngeal carcinoma growth by targeting phosphoinositide 3-kinase
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1069-6
FOXD3 may be a new cellular target biomarker as a hypermethylation gene in human ovarian cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0755-8
Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1)
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1062-0
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1009-5
MicroRNA-140-5p inhibits salivary adenoid cystic carcinoma progression and metastasis via targeting survivin
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1018-4
Phenyllactic acid promotes cell migration and invasion in cervical cancer via IKK/NF-κB-mediated MMP-9 activation
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0965-0
β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0873-3
Systematic analysis of gene expression profiles reveals prognostic stratification and underlying mechanisms for muscle-invasive bladder cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1056-y
Prognostic significance of cyclin D3 expression in malignancy patients: a meta-analysis
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0865-3
Leucine-rich repeat and sterile alpha motif containing 1 promotes the oncogenic growth of human hepatocellular carcinoma cells
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0976-x
Secretory leukocyte protease inhibitor suppresses HPV E6-expressing HNSCC progression by mediating NF-κB and Akt pathways
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0942-7
TGF-β1 stimulates epithelial–mesenchymal transition and cancer-associated myoepithelial cell during the progression from in situ to invasive breast cancer
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1068-7
Characteristics of a novel cell line ZJU-0430 established from human gallbladder carcinoma
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-0911-1
Retraction Note to: IL‑2 augments the sorafenib‑induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1083-8
Correlations between chromobox homolog 8 and key factors of epithelial–mesenchymal transition in hepatocellular carcinoma
来源期刊：Cancer Cell InternationalDOI：10.1186/s12935-019-1063-z
