Alimentary Pharmacology & Therapeutics is an international journal of gastroenterology and hepatology.The journal accepts original papers and systematic reviews concerned with clinical gastroenterology, hepatology and endoscopy.AP&T is particularly interested in therapies and diagnostics, including all aspects of translation from bench to bedside: identification of novel therapeutic targets, epidemiology, clinical trials, drug safety and meta-analyses.
《消化药理学与治疗学》是一本胃肠病学和肝病学的国际杂志。该杂志接受有关临床胃肠病学、肝病学和内窥镜检查的原创论文和系统综述。AP&T对治疗和诊断特别感兴趣,包括从实验室到床边的所有方面的翻译:新治疗靶点的确定、流行病学、临床试验、药物安全性和荟萃分析。
Serology‐based criteria for adult coeliac disease have excellent accuracy across the range of pre‐test probabilities
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15109
Impact of hepatitis B core‐related antigen on the incidence of hepatocellular carcinoma in patients treated with nucleos(t)ide analogues
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15108
Infliximab induction regimens in steroid‐refractory acute severe colitis: a multicentre retrospective cohort study with propensity score analysis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15456
Sustained virological response to hepatitis C treatment decreases the incidence of complications associated with type 2 diabetes
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15102
Three‐year effectiveness and safety of vedolizumab therapy for inflammatory bowel disease: a prospective multi‐centre cohort study
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15294
Long‐term metformin use may improve clinical outcomes in diabetic patients with non‐alcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15331
Myeloid‐derived suppressor cells induce regulatory T cells in chronically HBV infected patients with high levels of hepatitis B surface antigen and persist after antiviral therapy
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15226
Moderate to severe hepatic steatosis leads to overestimation of liver stiffness measurement in chronic hepatitis B patients without significant fibrosis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15298
Derivation and validation of a cardiovascular risk score for prediction of major acute cardiovascular events in non‐alcoholic fatty liver disease; the importance of an elevated mean platelet volume
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15192
Review article: unanswered clinical and research questions in autoimmune hepatitis‐conclusions of the International Autoimmune Hepatitis Group Research Workshop
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15111
Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15145
Quality of life measures predict mortality in patients with cirrhosis and severe ascites
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15084
Circulating microRNA146b‐5p is superior to C‐reactive protein as a novel biomarker for monitoring inflammatory bowel disease
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15159
Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and potential biomarkers
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15141
Endoscopic activity in asymptomatic patients with an ileal pouch is associated with an increased risk of pouchitis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15505
Review article: direct‐acting antivirals for the treatment of HCV during pregnancy and lactation ‐ implications for maternal dosing, foetal exposure, and safety for mother and child
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15476
Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15073
Patients with inflammatory bowel disease have an increased risk of myocardial infarction: a nationwide study
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15446
Systematic review with meta‐analysis: association between Helicobacter pylori CagA seropositivity and odds of inflammatory bowel disease
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15306
Review article: fungal alterations in inflammatory bowel diseases
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15523
LCR1 and LCR2, two multi‐analyte blood tests to assess liver cancer risk in patients without or with cirrhosis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15082
The effectiveness and safety of infliximab compared with biosimilar CT‐P13, in 3112 patients with ulcerative colitis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15323
Bile and fat excretion are biomarkers of clinically significant diarrhoea and constipation in irritable bowel syndrome
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15106
Obesity is associated with significantly increased risk for diarrhoea after controlling for demographic, dietary and medical factors: a cross‐sectional analysis of the 2009‐2010 National Health and Nutrition Examination Survey
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15500
Decreased neonatal hepatitis B virus (HBV) viremia by maternal tenofovir treatment predicts reduced chronic HBV infection in children born to highly viremic mothers
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15321
Sustained effectiveness, safety and therapeutic drug monitoring of tioguanine in a cohort of 274 IBD patients intolerant for conventional therapies
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15280
The antiviral effects of human microRNA miR‐302c‐3p against hepatitis B virus infection
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15197
A clinical decision support tool may help to optimise vedolizumab therapy in Crohn’s disease
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15609
Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15438
Editorial: liver transplantation for primary biliary cholangitis–the need for timely and more effective treatments
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15095
Vaccination for influenza and pneumococcus in patients with gastrointestinal cancer or inflammatory bowel disease: A prospective cohort study of methods for improving coverage
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15057
Letter: nonselective beta‐blockers, endoscopic therapy and portal vein thrombosis in cirrhosis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15236
Editorial: effects of vildagliptin on GLP‐1 levels, gastric motor function and food intake
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15206
Editorial: mesalazine and mucosal microbiome in quiescent ulcerative colitis—what can we learn?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15281
Letter: moderate‐to‐severe hepatic steatosis leads to overestimation of liver stiffness measurement in chronic hepatitis B patients without significant fibrosis
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15410
Editorial: combination immunosuppressive therapy to treat Crohn’s disease – ready for all age groups?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15259
Review article: the genetics of the human leucocyte antigen region in inflammatory bowel disease
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15485
Systematic review with meta‐analysis: high prevalence and cost of continued aminosalicylate use in patients with ulcerative colitis escalated to immunosuppressive and biological therapies
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15090
Editorial: the overlap between dyspepsia and gastro‐oesophageal reflux—is duodenal eosinophilia the missing link?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15388
Editorial: obesity and chronic diarrhoea—A Hill of evidence for causation?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15530
Editorial: infliximab de‐escalation in inflammatory bowel disease using a therapeutic drug monitoring strategy—early promise but more data needed
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15081
Letter: anti‐TNF therapy and intestinal resections in Crohn’s disease—are we just delaying the inevitable?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15482
Letter: you can stare at a vicious circle, but you can also try to break it—psychological health and coeliac disease
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15085
Editorial: tenofovir disoproxil fumarate and prevention of mother‐to‐child transmission of hepatitis B virus—authors’ reply
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15404
Letter: predictors of survival in patients undergoing transjugular intrahepatic portosystemic shunt—what should we assess by ultrasound?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15468
Editorial: should we abandon HCV genotype testing? Maybe
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15194
Letter: improvement of clinical outcomes by metformin in metabolic liver disease—a microbiota‐dependent mechanism?
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15391
Editorial: pressure to close the therapeutic window of non‐selective beta blockers? Authors’ reply
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15489
Editorial: mind the gaps ‐ an important first step towards improving hepatic encephalopathy care
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15290
Letter: should we delay surgery, or stop anti‐TNF therapy prior to elective surgical procedures in Crohn’s disease patients receiving anti‐TNF agents? Authors’ reply
来源期刊:Alimentary Pharmacology & TherapeuticsDOI:10.1111/apt.15487