The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.
《国际毒理学杂志》及时发表对毒理学家重要的当前主题的同行评审论文。六期双月刊涵盖广泛的主题,包括当代毒理学问题、安全性评估、毒理学测试的新方法、毒性机制、生物标志物和风险评估。该杂志还发表有关当代主题的特邀评论,并以专题讨论会为基础发表文章。此外,还定期出版各种专题的增刊,包括三份专门介绍化妆品审评专家组贡献的增刊。
Safety Assessment of Glycerin as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819883820
Toxicological Behavior of Gold Nanoparticles on Various Models: Influence of Physicochemical Properties and Other Factors
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819863130
Amended Safety Assessment of Methylisothiazolinone as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819838792
A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818813601
Investigating the Value of Urine Volume, Creatinine, and Cystatin C for Urinary Biomarkers Normalization for Drug Development Studies
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818819791
Toxicity of Flame Retardant Isopropylated Triphenyl Phosphate: Liver, Adrenal, and Metabolic Effects
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819851502
The Role of the Human Microbiome in Chemical Toxicity
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819849833
Naturally Occurring Level of Aflatoxin B1 Injures Human, Canine and Bovine Leukocytes Through ATP Depletion and Caspase Activation
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819892613
Addendum to Iwai and Hoberman (2014)—Reassessment of Developmental Toxicity of PFHxA in Mice
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819837904
β-N-methylamino-L-alanine Inhibits Human Catalase Activity: Possible Implications for Neurodegenerative Disease Development
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818821921
Evaluation of the Developmental Toxicity of Vedolizumab, an α4β7 Receptor Antagonist, in Rabbit and Nonhuman Primate
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819864105
Pharmacovigilance Assessment of Drug-Induced Acute Pancreatitis Using a Spontaneous Reporting Database
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819870717
Toxicological Assessment of a Standardized Boswellia serrata Gum Resin Extract
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819858069
Safety Assessment of Fatty Acid Amidopropyl Dimethylamines as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819836089
Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819827509
Confounding Factors in the Interpretation of Preclinical Studies
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819837157
An Alternative In Vitro Method for Examining Nanoparticle-Induced Cytotoxicity
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819859267
Effect of Subtoxic DDT Exposure on Glucose Uptake and Insulin Signaling in Rat L6 Myoblast-Derived Myotubes
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819850577
Biochemical and Electroretinographic Characterization of the Minipig Eye in the Context of Drug Safety Investigations
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819867929
Repeat-Dose Toxicity Study of a Lyophilized Recombinant Protective Antigen-Based Anthrax Vaccine Adjuvanted With CpG 7909
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819848722
Kidney Pathophysiology, Toxicology, and Drug-Induced Injury in Drug Development
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819831701
CDER Experience With Juvenile Animal Studies for CNS Drugs
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818824313
Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818814189
Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819862504
Nicotine-Induced Oxidative Stress in Human Primary Endometrial Cells
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819848081
Toxicity of Pexacerfont, a Corticotropin-Releasing Factor Type 1 Receptor Antagonist, in Rats and Dogs
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819827501
Integration of Consortia Recommendations for Justification of Animal Use Within Current and Future Drug Development Paradigms
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819852922
CNS Safety Screening Under ICH S7A Guidelines Requires Observations of Multiple Behavioral Units to Assess Motor Function
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819864836
A Global Overview of Poison Treatment Apps and Databases
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819827801
Effects of Perinatal Fluoride Exposure on Short- and Long-Term Memory, Brain Antioxidant Status, and Glutamate Metabolism of Young Rat Pups
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819857558
Analysis of a Skeletal Muscle Injury and Drug Interactions in Lovastatin- and Fenofibrate-Coadministered Dogs
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819844793
Prenatal Exposure to Cadmium During Organogenesis Impairs Memory in Young Rats
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819850579
Autophagy in Triptolide-Mediated Cytotoxicity in Hepatic Cells
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819864518
Evaluation of the Toxicity and Neurological Effects of Fulranumab in Adult Cynomolgus Monkeys
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819830980
Nonclinical Safety and Toxicokinetics of MnTE-2-PyP (BMX-010), a Topical Agent in Phase 2 Trials for Psoriasis and Atopic Dermatitis
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819852325
Trimethyltin (TMT) Reduces Testosterone Production in Adult Leydig Cells in Rats
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819870719
Changes in Ovarian and Uterine Morphology and Estrous Cycle in CD-1 Mice After Vanadium Inhalation
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819894529
Book Review: The Illustrated Dictionary of Toxicologic Pathology and Safety Science
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819880842
Evaluation of Juvenile Animal Studies for Pediatric CNS-Targeted Compounds: A Regulatory Perspective
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819883569
Thoughts From a Research Career by William Slikker Jr, the ATS 2019 Mildred S. Christian Career Achievement Award Winner
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819851780
Interspecies Comparison of Control Data From Embryo–Fetal Development Studies in Sprague-Dawley Rats, New Zealand White Rabbits, and Göttingen Minipigs
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819867249
Daily Intravenous Infusion of Busulfan Impurity 5 for 4 Days Is Not Associated With Toxic Effects in the Rat
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819888834
Safety Assessment of PCA (2-Pyrrolidone-5-Carboxylic Acid) and Its Salts as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819856568
Safety Study of Single-Dose Intravenously Administered DOTA-Siglec-9 Peptide in Sprague Dawley Rats
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581818821606
Safety Assessment of Camellia sinensis–Derived Ingredients As Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819889914
Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819889904
Language Consideration and Methodological Transparency in “Systematic” Reviews of Animal Toxicity Studies
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819827232
Safety Assessment of Sorbitan Esters as Used in Cosmetics
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819871877
Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819894281
Predicting the Need for a Tier II Ototoxicity Study From Early Renal Function Data
来源期刊:International Journal of ToxicologyDOI:10.1177/1091581819851232