The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality.The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research.All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
Spandidos Publications的主要目标是以清晰、简洁和客观的方式促进科学交流，同时努力提供高质量原创作品的及时出版。期刊主要集中在分子和实验医学、肿瘤学、临床和实验癌症治疗以及生物医学研究。Spandidos Publications有限公司出版的所有期刊均保持最高的质量标准。其编辑委员会成员都是世界著名的科学家。
lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.3975
Galectin-1 gene silencing inhibits the activation and proliferation but induces the apoptosis of hepatic stellate cells from mice with liver fibrosis
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.3950
Celecoxib inhibits the epithelial-to-mesenchymal transition in bladder cancer via the miRNA-145/TGFBR2/Smad3 axis
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4241
Bone morphogenetic protein 7 enhances the osteogenic differentiation of human dermal-derived CD105+ fibroblast cells through the Smad and MAPK pathways
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.3938
Crosstalk between mitogen-activated protein kinase inhibitors and transforming growth factor-β signaling results in variable activation of human dermal fibroblasts
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.3949
Rapamycin regulates the balance between cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4407
C1QTNF6 is overexpressed in gastric carcinoma and contributes to the proliferation and migration of gastric carcinoma cells.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2018.3978
SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPARα/FoxO1 signaling pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4059
Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4232
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4237
Identification of differentially expressed genes and preliminary validations in cardiac pathological remodeling induced by transverse aortic constriction
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4291
Piperlongumine induces autophagy in biliary cancer cells via reactive oxygen species-activated Erk signaling pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4324
DHA protects PC12 cells against oxidative stress and apoptotic signals through the activation of the NFE2L2/HO-1 axis.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4170
Aspirin alleviates orthopedic implant-associated infection
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4298
Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4131
Melatonin regulation of transcription in the reversal of morphine tolerance: Microarray analysis of differential gene expression
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.4030
Synergistic anticancer effect of acteoside and temozolomide-based glioblastoma chemotherapy.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4061
Downregulation of microRNA‑629‑5p in colorectal cancer and prevention of the malignant phenotype by direct targeting of low‑density lipoprotein receptor‑related protein 6.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4245
Sini San ameliorates duodenal mucosal barrier injury and low-grade inflammation via the CRF pathway in a rat model of functional dyspepsia
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4394
miR-19a promotes vascular smooth muscle cell proliferation, migration and invasion through regulation of Ras homolog family member B
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4357
Epigenetic regulation of COX-2 expression by DNA hypomethylation via NF-κB activation in ketamine-induced ulcerative cystitis
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4252
Suppressive effect mediated by human adipose-derived stem cells on T cells involves the activation of JNK
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2018.3953
MicroRNA-9-5p downregulates Klf4 and influences the progression of hepatocellular carcinoma via the AKT signaling pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4062
Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4307
Erythropoietin suppresses hepatic steatosis and obesity by inhibiting endoplasmic reticulum stress and upregulating fibroblast growth factor 21
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4210
The role of antimiR-26a-5p/biphasic calcium phosphate in repairing rat femoral defects
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4249
SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4250
Characteristic genes in THP-1 derived macrophages infected with Mycobacterium tuberculosis H37Rv strain identified by integrating bioinformatics methods
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4293
Upregulation of interleukin-8 and activin A induces osteoclastogenesis in ameloblastoma
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4171
Gene networking in colistin-induced nephrotoxicity reveals an adverse outcome pathway triggered by proteotoxic stress
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4052
Analysis of a nanoparticle-enriched fraction of plasma reveals miRNA candidates for Down syndrome pathogenesis
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4222
Weighted gene co-expression network analysis to identify key modules and hub genes associated with atrial fibrillation
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4416
Brca1 is involved in tolerance to adefovir dipivoxil‑induced DNA damage.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4164
EGFR monoclonal antibody panitumumab inhibits chronic proliferative cholangitis by downregulating EGFR
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4190
Resveratrol‑loaded nanoparticles inhibit enterovirus 71 replication through the oxidative stress‑mediated ERS/autophagy pathway.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4211
The efficacy of cisplatin on nasopharyngeal carcinoma cells may be increased via the downregulation of fibroblast growth factor receptor 2
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4193
Overexpression of miR-200a-3p promoted inflammation in sepsis-induced brain injury through ROS-induced NLRP3
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4326
Improved HCN channels in pyramidal neurons and their new expression levels in pericytes and astrocytes in the gerbil hippocampal CA1 subfield following transient ischemia
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4353
MyD88 mediates colorectal cancer cell proliferation, migration and invasion via NF-κB/AP-1 signaling pathway
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4390
Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4414
Suppressing serum response factor inhibits invasion in cervical cancer cell lines via regulating Egr‑1 and epithelial-mesenchymal transition.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2018.3954
Construction of a long non-coding RNA-mediated transcription factor and gene regulatory triplet network reveals global patterns and biomarkers for ischemic stroke
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4421
Sequence analysis of the Pre-S gene in chronic asymptomatic HBV carriers with low-level HBsAg
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4055
Simvastatin promotes endothelial dysfunction by activating the Wnt/β-catenin pathway under oxidative stress
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4310
Micro-dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4251
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4400
Redd1 protects against post-infarction cardiac dysfunction by targeting apoptosis and autophagy
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4366
Novel iridium (III)-derived organometallic compound for the inhibition of human platelet activation
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4177
Silencing of synaptotagmin 13 inhibits tumor growth through suppressing proliferation and promoting apoptosis of colorectal cancer cells
来源期刊：International Journal of Molecular MedicineDOI：10.3892/ijmm.2019.4412
MicroRNA‑432 inhibits the aggressiveness of glioblastoma multiforme by directly targeting IGF‑1R.
来源期刊：International journal of molecular medicineDOI：10.3892/ijmm.2019.4429
