International Immunopharmacology is the primary vehicle for the publication of original research papers pertinent to the overlapping areas of immunology, pharmacology, cytokine biology, immunotherapy, immunopathology and immunotoxicology. Review articles that encompass these subjects are also welcome.The subject material appropriate for submission includes:• Clinical studies employing immunotherapy of any type including the use of: bacterial and chemical agents; thymic hormones, interferon, lymphokines, etc., in transplantation and diseases such as cancer, immunodeficiency, chronic infection and allergic, inflammatory or autoimmune disorders.• Studies on the mechanisms of action of these agents for specific parameters of immune competence as well as the overall clinical state.• Pre-clinical animal studies and in vitro studies on mechanisms of action with immunopotentiators, immunomodulators, immunoadjuvants and other pharmacological agents active on cells participating in immune or allergic responses.• Pharmacological compounds, microbial products and toxicological agents that affect the lymphoid system, and their mechanisms of action.• Agents that activate genes or modify transcription and translation within the immune response.• Substances activated, generated, or released through immunologic or related pathways that are pharmacologically active.• Production, function and regulation of cytokines and their receptors.• Classical pharmacological studies on the effects of chemokines and bioactive factors released during immunological reactions.
国际免疫药理学是发表与免疫学、药理学、细胞因子生物学、免疫治疗、免疫病理学和免疫毒理学重叠领域相关的原创研究论文的主要载体。包含这些主题的综述文章也是受欢迎的。适合提交的主题材料包括：·使用任何类型的免疫疗法的临床研究，包括使用：细菌和化学试剂;胸腺激素、干扰素、淋巴因子等，移植和疾病，如癌症、免疫缺陷、慢性感染和过敏、炎症或自身免疫性疾病。·研究这些药物对免疫能力的特定参数以及总体临床状态的作用机制。·免疫增强剂、免疫调节剂、免疫佐剂和其他对参与免疫或过敏反应的细胞具有活性的药理学药物的作用机制的临床前动物研究和体外研究。·影响淋巴系统的药理学化合物、微生物制品和毒物及其作用机制。·激活基因或修改免疫应答中的转录和翻译的药剂。·通过免疫或相关途径激活、生成或释放的具有药理学活性的物质。·细胞因子及其受体的产生、功能和调节。·免疫反应中释放的趋化因子和生物活性因子作用的经典药理学研究。
Inhibition of GSK‐3&bgr; alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2018.12.042
Pidotimod, an immunostimulant in pediatric recurrent respiratory tract infections: A meta-analysis of randomized controlled trials.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2018.11.043
Pseudoginsenoside-F11 attenuates cognitive impairment by ameliorating oxidative stress and neuroinflammation in d‑galactose-treated mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2018.11.026
Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin inflammation in mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105682
BMP9 inhibits the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis via the PI3K/AKT signaling pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105685
Febuxostat attenuates ulcerative colitis by the inhibition of NF-κB, proinflammatory cytokines, and oxidative stress in mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105884
Resolvin D1 (RvD1) and maresin 1 (Mar1) contribute to human macrophage control of M. tuberculosis infection while resolving inflammation.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105694
Epicatechin alleviates inflammation in lipopolysaccharide‐induced acute lung injury in mice by inhibiting the p38 MAPK signaling pathway
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2018.11.016
Maresin 1 alleviates dextran sulfate sodium-induced ulcerative colitis by regulating NRF2 and TLR4/NF-kB signaling pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106018
Genipin protects rats against lipopolysaccharide-induced acute lung injury by reinforcing autophagy.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.052
PIM1 inhibitor SMI-4a attenuated lipopolysaccharide-induced acute lung injury through suppressing macrophage inflammatory responses via modulating p65 phosphorylation.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.05.040
CD5L contributes to the pathogenesis of methicillin-resistant Staphylococcus aureus-induced pneumonia.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.057
Immunopathological effects of Agaricus blazei Murill polysaccharides against Schistosoma mansoni infection by Th1 and NK1 cells differentiation.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.05.045
Sinomenine hydrochloride inhibits the progression of plasma cell mastitis by regulating IL-6/JAK2/STAT3 pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106025
MCP-induced protein 1 attenuates sepsis-induced acute lung injury by modulating macrophage polarization via the JNK/c-Myc pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105741
Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K/AKT pathway in acute lung injury.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105842
Kakkalide and irisolidone alleviate 2,4,6-trinitrobenzenesulfonic acid-induced colitis in mice by inhibiting lipopolysaccharide binding to toll-like receptor-4 and proteobacteria population.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.05.008
Exopolysaccharides from Cyanobacterium aponinum induce a regulatory dendritic cell phenotype and inhibit SYK and CLEC7A expression in dendritic cells, T cells and keratinocytes
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2019.01.044
Preclinical development of the TLR9 agonist DV281 as an inhaled aerosolized immunotherapeutic for lung cancer: Pharmacological profile in mice, non‐human primates, and human primary cells
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2018.11.019
C1q/TNF-related protein-9 attenuates atherosclerosis through AMPK-NLRP3 inflammasome singling pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105934
Parthenolide, an NF-κB inhibitor, alleviates peritoneal fibrosis by suppressing the TGF-β/Smad pathway.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106064
S-Allylmercaptocysteine attenuates Bleomycin-induced pulmonary fibrosis in mice via suppressing TGF-β1/Smad and oxidative stress pathways.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106110
Isosalvianolic acid C-induced pseudo-allergic reactions via the mast cell specific receptor MRGPRX2.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.013
Long-lasting protective immunity against H7N9 infection is induced by intramuscular or CpG-adjuvanted intranasal immunization with the split H7N9 vaccine.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106013
Eupatilin protects chondrocytes from apoptosis via activating sestrin2-dependent autophagy.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105748
Bortezomib ameliorates acute allograft rejection after renal transplant by inhibiting Tfh cell proliferation and differentiation via miR-15b/IRF4 axis.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105758
Phenobarbital inhibits osteoclast differentiation and function through NF‐&kgr;B and MAPKs signaling pathway
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2019.01.033
Novel antibody against oligomeric amyloid-β: Insight into factors for effectively reducing the aggregation and cytotoxicity of amyloid-β aggregates.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2018.12.014
Role of Galphaq in pathogenesis of psoriasis, a new mechanism about the immune regulation in psoriasis
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2018.12.054
Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.049
Zileuton ameliorates depressive-like behaviors, hippocampal neuroinflammation, apoptosis and synapse dysfunction in mice exposed to chronic mild stress.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105947
Umbelliferone reduces the expression of inflammatory chemokines in HaCaT cells and DNCB/DFE-induced atopic dermatitis symptoms in mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105830
Dendritic cells modified with Der p1 antigen as a therapeutic potential for allergic rhinitis in a murine model via regulatory effects on IL‐4, IL‐10 and IL‐13
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2019.02.045
Treponema pallidum enhances human monocyte migration and invasion by dysregulating the MMP/TIMP balance.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105744
TGR5 agonist INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.02.044
MPMBP down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB but not AP-1 activation.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106085
The nitrated fatty acid, 10-nitrooleate inhibits the neutrophil chemotaxis via peroxisome proliferator-activated receptor gamma in CLP-induced sepsis in mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.04.001
The role of kinin B1 and B2 receptors in the mouse model of oxazolone-induced atopic dermatitis.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.063
Fusion of thymosin alpha 1 with mutant IgG1 CH3 prolongs half-life and enhances antitumor effects in vivo.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.05.047
Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105968
Caffeine-enhanced anti-tumor activity of anti-PD1 monoclonal antibody.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106002
Semaphorin 4A acts in a feed‐forward loop with NF‐&kgr;B pathway to exacerbate catabolic effect of IL‐1&bgr; on chondrocytes
来源期刊：International ImmunopharmacologyDOI：10.1016/j.intimp.2019.01.006
cGMP signaling pathway in hepatic encephalopathy neuroinflammation and cognition.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106082
Cluster binding studies with two anti-Thomsen-Friedenreich (anti-core-1, CD176, TF) antibodies: Evidence for a multiple TF epitope.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.058
Triptolide ameliorates lupus via the induction of miR-125a-5p mediating Treg upregulation.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.02.047
Type II hypersensitivity reactions after oxaliplatin rechallenge can be life threatening.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105728
Vitamin D3 induces the expression of membrane progesterone receptors (mPRs) on naive CD4+ T lymphocyte cells in women of reproductive age.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.03.053
The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106086
Immunomodulatory effects of dietary IMUNO-2865 in mice, pre-and post-vaccine challenge with parainfluenza virus 5.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.105846
The increased marginal zone B cells attenuates early inflammatory responses during sepsis in Gpr174 deficient mice.
来源期刊：International immunopharmacologyDOI：10.1016/j.intimp.2019.106034
