Molecular and Cellular Biology (MCB) showcases significant discoveries in cellular morphology and function, genome organization, regulation of genetic expression, morphogenesis, and somatic cell genetics. The journal also examines viral systems, publishing papers that emphasize their impact on the cell.
分子和细胞生物学(MCB)展示了细胞形态和功能、基因组组织、基因表达调控、形态发生和体细胞遗传学方面的重大发现。该杂志还研究病毒系统,发表论文强调它们对细胞的影响。
Transcriptional and Epigenomic Regulation of Adipogenesis
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00601-18
Transcriptome-Wide Comparison of Stress Granules and P-Bodies Reveals that Translation Plays a Major Role in RNA Partitioning
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00313-19
RNA Binding Protein HuR Promotes Autophagosome Formation by Regulating Expression of Autophagy-Related Proteins 5, 12, and 16 in Human Hepatocellular Carcinoma Cells
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00508-18
ESR1-Stabilizing Long Noncoding RNA TMPO-AS1 Promotes Hormone-Refractory Breast Cancer Progression
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00261-19
MicroRNA (miRNA)-to-miRNA Regulation of Programmed Cell Death 4 (PDCD4)
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00086-19
Long Noncoding RNA H19 Promotes Tumorigenesis of Multiple Myeloma by Activating BRD4 Signaling by Targeting MicroRNA 152-3p
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00382-19
MiR-7 impairs insulin signaling and regulates Aβ levels through posttranscriptional regulation of the IRS-2, INSR, IDE and LXR pathway.
来源期刊:Molecular and cellular biologyDOI:10.1128/MCB.00170-19
EWSR1-FLI1 Activation of the Cancer/Testis Antigen FATE1 Promotes Ewing Sarcoma Survival
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00138-19
Distinct Functions of the Cap-Binding Complex in Stimulation of Nuclear mRNA Export
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00540-18
Dynamic Methylation of an L1 Transduction Family during Reprogramming and Neurodifferentiation
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00499-18
Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00203-19
IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00528-18
Hypoxic Environment Promotes Barrier Formation in Human Intestinal Epithelial Cells through Regulation of MicroRNA 320a Expression
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00553-18
Functional Screening Identifies MicroRNA Regulators of Corin Activity and Atrial Natriuretic Peptide Biogenesis
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00271-19
Long Noncoding RNA HOTAIR Promotes Endometrial Carcinoma Cell Proliferation by Binding to PTEN via the Activating Phosphatidylinositol 3-Kinase/Akt Signaling Pathway
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00251-19
Long Noncoding RNA HOXA-AS3 Integrates NF-κB Signaling To Regulate Endothelium Inflammation
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00139-19
CKAP4 Regulates Cell Migration via the Interaction with and Recycling of Integrin
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00073-19
Structure of Fission Yeast Transcription Factor Pho7 Bound to pho1 Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00132-19
SRSF1 and PTBP1 Are trans-Acting Factors That Suppress the Formation of a CD33 Splicing Isoform Linked to Alzheimer’s Disease Risk
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00568-18
Reactive Oxygen Species Signaling Promotes Hypoxia-Inducible Factor 1α Stabilization in Sonic Hedgehog-Driven Cerebellar Progenitor Cell Proliferation
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00268-18
FANCD2 Binding to H4K20me2 via a Methyl-Binding Domain Is Essential for Efficient DNA Cross-Link Repair
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00194-19
Erratum for Sehrawat et al., “Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes”
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00049-19
Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00527-18
Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00451-18
The Role of Metabolic Flexibility in the Regulation of the DNA Damage Response by Nitric Oxide
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00153-19
Aryl Hydrocarbon Receptor Directly Regulates Artemin Gene Expression
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00190-19
TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00593-18
Correction for Minocha et al., “Rapid Recapitulation of Nonalcoholic Steatohepatitis upon Loss of Host Cell Factor 1 Function in Mouse Hepatocytes”
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00127-19
CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00225-18
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00554-18
GP78 Cooperates with Dual-Specificity Phosphatase 1 To Stimulate Epidermal Growth Factor Receptor-Mediated Extracellular Signal-Regulated Kinase Signaling
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00485-18
Long Noncoding RNA FAM83H-AS1 Modulates SpA-Inhibited Osteogenic Differentiation in Human Bone Mesenchymal Stem Cells
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00362-19
The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling Pathways
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00391-18
The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00320-19
ARS2 Regulates Nuclear Paraspeckle Formation through 3′-End Processing and Stability of NEAT1 Long Noncoding RNA
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00269-19
ZFP281 Recruits MYC to Active Promoters in Regulating Transcriptional Initiation and Elongation
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00329-19
Correction for Gallo et al., “RACK1 Specifically Regulates Translation through Its Binding to Ribosomes”
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00544-18
CKS1 Germ Line Exclusion Is Essential for the Transition from Meiosis to Early Embryonic Development
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00590-18
Soluble Heparin Binding Epidermal Growth Factor-Like Growth Factor Is a Regulator of GALGT2 Expression and GALGT2-Dependent Muscle and Neuromuscular Phenotypes
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00140-19
Bugs as Cancer Drugs: Challenges and Opportunities
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00206-19
Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00436-19
Tsr4 Is a Cytoplasmic Chaperone for the Ribosomal Protein Rps2 in Saccharomyces cerevisiae
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00094-19
Articles of Significant Interest in This Issue
来源期刊:Molecular and Cellular BiologyDOI:10.1128/mcb.00051-19
PLAG attenuates STZ-induced pancreatic beta cell damage by promoting GLUT2 endocytosis.
来源期刊:Molecular and cellular biologyDOI:10.1128/MCB.00157-19
Priming phosphorylation of TBK1 by IKKβ is essential in TLR3/4 signaling.
来源期刊:Molecular and cellular biologyDOI:10.1128/MCB.00509-19
Transcriptional Suppression of CPI-17 Gene Expression in Vascular Smooth Muscle Cells by Tumor Necrosis Factor, Krüppel-Like Factor 4, and Sp1 Is Associated with Lipopolysaccharide-Induced Vascular Hypocontractility, Hypotension, and Mortality
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00070-19
Articles of Significant Interest in This Issue
来源期刊:Molecular and Cellular BiologyDOI:10.1128/mcb.00333-19
Function of the MYND Domain and C-Terminal Region in Regulating the Subcellular Localization and Catalytic Activity of the SMYD Family Lysine Methyltransferase Set5
来源期刊:Molecular and Cellular BiologyDOI:10.1128/MCB.00341-19