Protein Science, the flagship journal of The Protein Society, serves an international forum for publishing original reports on all scientific aspects of protein molecules. The Journal publishes papers by leading scientists from all over the world that report on advances in the understanding of proteins in the broadest sense. Protein Science aims to unify this field by cutting across established disciplinary lines and focusing on “protein-centered” science.The Journal encompasses the structure, function, and biochemical significance of proteins, their role in molecular and cell biology, genetics, and evolution, and their regulation and mechanisms of action.
《蛋白质科学》是蛋白质学会的旗舰期刊，是发表蛋白质分子所有科学方面原创报告的国际论坛。该杂志发表来自世界各地的领先科学家的论文，报告在最广泛的意义上对蛋白质的理解的进展。《蛋白质科学》旨在通过跨越既定的学科界限并专注于“以蛋白质为中心”的科学来统一这一领域。该杂志涵盖了蛋白质的结构、功能和生化意义，它们在分子和细胞生物学、遗传学和进化中的作用，以及它们的调节和作用机制。
Molybdenum‐ and tungsten‐containing formate dehydrogenases and formylmethanofuran dehydrogenases: Structure, mechanism, and cofactor insertion
来源期刊：Protein ScienceDOI：10.1002/pro.3498
The role of protein complexes in human genetic disease
来源期刊：Protein ScienceDOI：10.1002/pro.3667
An overview of structure, function, and regulation of pyruvate kinases
来源期刊：Protein ScienceDOI：10.1002/pro.3691
Ribosome protection by ABC‐F proteins—Molecular mechanism and potential drug design
来源期刊：Protein ScienceDOI：10.1002/pro.3589
Molecular basis for chromatin assembly and modification by multiprotein complexes
来源期刊：Protein ScienceDOI：10.1002/pro.3535
Substrate selection by the proteasome through initiation regions
来源期刊：Protein ScienceDOI：10.1002/pro.3642
Transition of the prion protein from a structured cellular form (PrPC) to the infectious scrapie agent (PrPSc)
来源期刊：Protein ScienceDOI：10.1002/pro.3735
Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase
来源期刊：Protein ScienceDOI：10.1002/pro.3571
Bridging protein structure, dynamics, and function using hydrogen/deuterium‐exchange mass spectrometry
来源期刊：Protein ScienceDOI：10.1002/pro.3790
The vexing complexity of the amyloidogenic pathway
来源期刊：Protein ScienceDOI：10.1002/pro.3606
Crystal structure of a Vip3B family insecticidal protein reveals a new fold and a unique tetrameric assembly
来源期刊：Protein ScienceDOI：10.1002/pro.3803
Instability in a coiled‐coil signaling helix is conserved for signal transduction in soluble guanylyl cyclase
来源期刊：Protein ScienceDOI：10.1002/pro.3707
Molstack: A platform for interactive presentations of electron density and cryo‐EM maps and their interpretations
来源期刊：Protein ScienceDOI：10.1002/pro.3747
Structural basis of generic versus specific E2–RING E3 interactions in protein ubiquitination
来源期刊：Protein ScienceDOI：10.1002/pro.3690
Effects of histatin 5 modifications on antifungal activity and kinetics of proteolysis
来源期刊：Protein ScienceDOI：10.1002/pro.3767
Structural basis of chemokine and receptor interactions: Key regulators of leukocyte recruitment in inflammatory responses
来源期刊：Protein ScienceDOI：10.1002/pro.3744
Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities
来源期刊：Protein ScienceDOI：10.1002/pro.3759
Gauge PDE and AKSZ‐type Sigma Models
来源期刊：Protein ScienceDOI：10.1002/prop.201910007
‐Bootstrap Approach to Non‐Commutative Gauge Theories
来源期刊：Protein ScienceDOI：10.1002/prop.201910010
IDDomainSpotter: Compositional bias reveals domains in long disordered protein regions—Insights from transcription factors
来源期刊：Protein ScienceDOI：10.1002/pro.3754
A cryptic activity in the Nudix hydrolase superfamily
来源期刊：Protein ScienceDOI：10.1002/pro.3666
Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
来源期刊：Protein ScienceDOI：10.2210/PDB6DQP/PDB
Higher Structures in M‐Theory: LMS/EPSRC Durham Symposium on Higher Structures in M‐Theory
来源期刊：Protein ScienceDOI：10.1002/prop.201910001
A three‐dimensional potential of mean force to improve backbone and sidechain hydrogen bond geometry in Xplor‐NIH protein structure determination
来源期刊：Protein ScienceDOI：10.1002/pro.3745
Crystal structure of the apo form of a beta-transaminase from Mesorhizobium sp. strain LUK.
来源期刊：Protein ScienceDOI：10.2210/PDB6IZ9/PDB
Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition
来源期刊：Protein ScienceDOI：10.1002/pro.3798
Electron‐deficient p‐benzoyl‐l‐phenylalanine derivatives increase covalent chemical capture yields for protein–protein interactions
来源期刊：Protein ScienceDOI：10.1002/pro.3621
Human MICAL1: Activation by the small GTPase Rab8 and small‐angle X‐ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8
来源期刊：Protein ScienceDOI：10.1002/pro.3512
Identification of a α‐helical molten globule intermediate and structural characterization of β‐cardiotoxin, an all β‐sheet protein isolated from the venom of Ophiophagus hannah (king cobra)
来源期刊：Protein ScienceDOI：10.1002/pro.3605
Predicting and validating a model of suppressor of IKKepsilon through biophysical characterization
来源期刊：Protein ScienceDOI：10.1002/pro.3640
The role of calcium in the interaction between calmodulin and a minimal functional construct of eukaryotic elongation factor 2 kinase
来源期刊：Protein ScienceDOI：10.1002/pro.3753
OPUS‐SSF: A side‐chain‐inclusive scoring function for ranking protein structural models
来源期刊：Protein ScienceDOI：10.1002/pro.3608
Selection and analyses of variants of a designed protein suggest importance of hydrophobicity of partially buried sidechains for protein stability at high temperatures
来源期刊：Protein ScienceDOI：10.1002/pro.3643
Steric hindrance controls pyridine nucleotide specificity of a flavin-dependent NADH:quinone oxidoreductase.
来源期刊：Protein ScienceDOI：10.2210/PDB6E2A/PDB
Long‐range molecular dynamics show that inactive forms of Protein Kinase A are more dynamic than active forms
来源期刊：Protein ScienceDOI：10.1002/pro.3556
Kinetic versus thermodynamic control of mutational effects on protein homeostasis: A perspective from computational modeling and experiment
来源期刊：Protein ScienceDOI：10.1002/pro.3639
Characterization and structure determination of prolyl‐tRNA synthetase from Pseudomonas aeruginosa and development as a screening platform
来源期刊：Protein ScienceDOI：10.1002/pro.3579
Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis
来源期刊：Protein ScienceDOI：10.1002/pro.3813
Flavin oxidation in flavin‐dependent N‐monooxygenases
来源期刊：Protein ScienceDOI：10.1002/pro.3487
Fine mapping of hydrophobic contacts reassesses the organization of the first three dystrophin coiled‐coil repeats
来源期刊：Protein ScienceDOI：10.1002/pro.3557
Hydrophobic residues of melittin mediate its binding to αA−crystallin
来源期刊：Protein ScienceDOI：10.1002/pro.3792
Tyrosine substitution of a conserved active‐site histidine residue activates Plasmodium falciparum peroxiredoxin 6
来源期刊：Protein ScienceDOI：10.1002/pro.3490
ProtaBank: A repository for protein design and engineering data
来源期刊：Protein ScienceDOI：10.1002/pro.3585
Structures of single‐layer β‐sheet proteins evolved from β‐hairpin repeats
来源期刊：Protein ScienceDOI：10.1002/pro.3683
Chimeric dihydrofolate reductases display properties of modularity and biophysical diversity
来源期刊：Protein ScienceDOI：10.1002/pro.3646
Stability of Aβ‐fibril fragments in the presence of fatty acids
来源期刊：Protein ScienceDOI：10.1002/pro.3719
Context and number of noncanonical repeat variable diresidues impede the design of TALE proteins with improved DNA targeting
来源期刊：Protein ScienceDOI：10.1002/pro.3801
Human serum albumin presents isoform variants with altered neonatal Fc receptor interactions
来源期刊：Protein ScienceDOI：10.1002/pro.3733
Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase
来源期刊：Protein ScienceDOI：10.1002/pro.3748
Structural and functional characterization of a novel acidophilic 7α‐hydroxysteroid dehydrogenase
来源期刊：Protein ScienceDOI：10.1002/pro.3599
