Medicinal Research Reviews publishes timely, critical reviews and opinion-based articles on topics related to medicinal research, broadly defined, to which the authors have made significant contributions.Appropriate topics include, but are not limited to, the underlying pathophysiology of important diseases and disease vectors; therapeutic approaches to the treatment of various diseases; the properties of molecular targets for therapeutic agents; important new methodologies facilitating the search for therapies; genomics and proteomics; structure-activity correlations of drug series; the development of new imaging and diagnostic tools; drug metabolism; drug delivery; and chemical, pharmacological, pharmacokinetic, pharmacodynamic, and clinical characteristics of important drugs.Articles are mainly solicited by the Editors; however, voluntary contributions are also encouraged. In the latter case, potential authors are asked to contact the Editor-in-chief with an outline (see below) before beginning to write in order to avoid duplication of effort and to ensure suitability of the topic and the level of coverage.
《医学研究评论》及时发表与医学研究相关的评论和观点性文章，广泛定义，作者对此做出了重大贡献。适当的主题包括但不限于重要疾病和病媒的潜在病理生理学;治疗各种疾病的治疗方法;治疗剂的分子靶的性质;促进治疗研究的重要新方法;基因组学和蛋白质组学;系列药物的构效关系;开发新的成像和诊断工具;药物代谢;药物递送;以及重要药物的化学、药理、药代动力学、药效学和临床特点。但也鼓励自愿捐款。在后一种情况下，为了避免重复工作，并确保主题和覆盖范围的适当性，要求潜在作者在开始写作之前与主编联系，并提供大纲（见下文）。
Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21528
Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21542
Recent clinical trends in Toll‐like receptor targeting therapeutics
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21553
Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21572
Selective targeting of antiapoptotic BCL‐2 proteins in cancer
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21516
Small molecule inhibitors of epithelial‐mesenchymal transition for the treatment of cancer and fibrosis
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21596
Complex roles of the old drug aspirin in cancer chemoprevention and therapy
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21514
Phage therapy: Current status and perspectives
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21593
Antiaging effects of bioactive molecules isolated from plants and fungi
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21559
Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21511
Targeting autophagy enhances the anticancer effect of artemisinin and its derivatives
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21580
Melatonin mediates mucosal immune cells, microbial metabolism, and rhythm crosstalk: A therapeutic target to reduce intestinal inflammation
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21628
Efflux pump inhibitors of clinically relevant multidrug resistant bacteria
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21591
Design and synthesis of glycomimetics: Recent advances
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21625
Death‐associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21518
Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21512
Drug delivery systems designed to overcome antimicrobial resistance
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21588
Small‐molecule inhibitors of multidrug resistance‐associated protein 1 and related processes: A historic approach and recent advances
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21510
Lipidic prodrug approach for improved oral drug delivery and therapy
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21533
Mechanisms and pathways of anti‐inflammatory activity of DPP‐4 inhibitors in cardiovascular and renal protection
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21513
Intramolecular hydrogen bonding: An opportunity for improved design in medicinal chemistry
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21562
Agonists and inhibitors of the STING pathway: Potential agents for immunotherapy
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21649
Development and therapeutic potential of autotaxin small molecule inhibitors: From bench to advanced clinical trials
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21551
Repurposing approved drugs on the pathway to novel therapies
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21627
Alternative oxidase inhibitors: Mitochondrion‐targeting as a strategy for new drugs against pathogenic parasites and fungi
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21560
Targeting MDM2 for novel molecular therapy: Beyond oncology
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21637
Molecules targeting the androgen receptor (AR) signaling axis beyond the AR‐Ligand binding domain
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21548
Orexin supplementation in narcolepsy treatment: A review
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21550
Hybrid molecules with potential in vitro antiplasmodial and in vivo antimalarial activity against drug‐resistant Plasmodium falciparum
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21643
Therapeutic strategies for targeting telomerase in cancer
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21626
Progress in the application of CRISPR: From gene to base editing
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21537
Carbon monoxide: An emerging therapy for acute kidney injury
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21650
Chemical space of Escherichia coli dihydrofolate reductase inhibitors: New approaches for discovering novel drugs for old bugs
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21538
Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain and muscle
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21590
The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21601
Norovirus antivirals: Where are we now?
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21545
Polyphenolic natural products and natural product–inspired steroidal mimics as aromatase inhibitors
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21536
Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21541
Challenges and approaches in the discovery of human immunodeficiency virus type‐1 non‐nucleoside reverse transcriptase inhibitors
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21544
Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21546
Bioactive peptides and proteins as alternative antiplatelet drugs
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21579
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21646
The aryl hydrocarbon receptor (AhR) as a breast cancer drug target
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21645
The mitochondrial permeability transition pore in cell death: A promising drug binding bioarchitecture
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21635
Recent advances in the development of nanoparticles for multimodality imaging and therapy of cancer
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21642
Strategies for developing pregnane X receptor antagonists: Implications from metabolism to cancer
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21648
Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21594
Imaging metabotropic glutamate receptor system: Application of positron emission tomography technology in drug development
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21566
Targeting virulence factors as an antimicrobial approach: Pigment inhibitors
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21621
Synthesis of histidine kinase inhibitors and their biological properties
来源期刊：Medicinal Research ReviewsDOI：10.1002/med.21651
