The journal Immunopharmacology and Immunotoxicology is devoted to pre-clinical and clinical drug discovery and development targeting the immune system. Research related to the immunoregulatory effects of various compounds, including small-molecule drugs and biologics, on immunocompetent cells and immune responses, as well as the immunotoxicity exerted by xenobiotics and drugs. Only research that describe the mechanisms of specific compounds (not extracts) is of interest to the journal.The journal will prioritise preclinical and clinical studies on immunotherapy of disorders such as chronic inflammation, allergy, autoimmunity, cancer etc. The effects of small-drugs, vaccines and biologics against central immunological targets as well as cell-based therapy, including dendritic cell therapy, T cell adoptive transfer and stem cell therapy, are topics of particular interest. Publications pointing towards potential new drug targets within the immune system or novel technology for immunopharmacological drug development are also welcome.With an immunoscience focus on drug development, immunotherapy and toxicology, the journal will cover areas such as infection, allergy, inflammation, tumor immunology, degenerative disorders, immunodeficiencies, neurology, atherosclerosis and more.Immunopharmacology and Immunotoxicology will accept original manuscripts, brief communications, commentaries, mini-reviews, reviews, clinical trials and clinical cases, on the condition that the results reported are based on original, clinical, or basic research that has not been published elsewhere in any journal in any language (except in abstract form relating to paper communicated to scientific meetings and symposiums).
免疫药理学和免疫毒理学杂志致力于临床前和临床药物的发现和开发靶向免疫系统。研究各种化合物（包括小分子药物和生物制剂）对免疫活性细胞和免疫应答的免疫调节作用，以及异生物质和药物的免疫毒性。仅描述特定化合物机制的研究（非摘录）是该杂志感兴趣的内容。该杂志将优先介绍慢性炎症、过敏、自身免疫、癌症等疾病的免疫治疗的临床前和临床研究。针对中枢免疫靶点的小药物、疫苗和生物制剂以及基于细胞的治疗（包括树突状细胞治疗）的效果。T细胞过继转移和干细胞治疗是特别感兴趣的主题。同时，我们也欢迎发表有关免疫系统内潜在新药靶点或免疫药理学药物开发新技术的文章。免疫科学的重点是药物开发、免疫治疗和毒理学，该杂志将涵盖感染、过敏、炎症、肿瘤免疫学、退行性疾病、免疫缺陷、神经病学、动脉粥样硬化等领域。免疫药理学和免疫毒理学将接受原始手稿，简要通信、评论、小型综述、综述、临床试验和临床病例，条件是报告的结果基于原创、临床或基础研究，且未以任何语言在任何期刊上发表（与传达给科学会议和研讨会的论文相关的摘要形式除外）。
Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1568451
Carvacrol ameliorates the progression of liver fibrosis through targeting of Hippo and TGF-β signaling pathways in carbon tetrachloride (CCl4)-induced liver fibrosis in rats
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1566926
Inflammatory mediators in exhaled breath condensate and peripheral blood of healthy donors and stable COPD patients
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1609496
The role of T helper 17 and regulatory T cells in tumor microenvironment
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1566925
The effects of cadmium exposure in the induction of inflammation
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1697284
Effects of sitagliptin and vitamin D3 on T helper cell transcription factors and cytokine production in clinical subgroups of type 2 diabetes mellitus: highlights upregulation of FOXP3 and IL-37
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1593447
Leukemia inhibitory factor (LIF) modulates the development of dendritic cells in a dual manner
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1619761
Alpha-momorcharin regulates cytokine expression and induces apoptosis in monocytes
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1610430
Rheumatoid arthritis and cognition dysfunction: lack of association with cumulative glucocorticoid use
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1679170
Co-administration of resveratrol and beta-aminopropionitrile attenuates liver fibrosis development via targeting lysyl oxidase in CCl4-induced liver fibrosis in rats
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1688829
Anti-inflammatory potential of pyocyanin in LPS-stimulated murine macrophages
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1555845
Anti-inflammatory effect of 3,7-dimethyl-1,8-hydroxy-6-methoxyisochroman via nuclear factor erythroid 2-like 2-mediated heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 and BV2 cells
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1608559
XAV939, a Wnt/β-catenin pathway modulator, has inhibitory effects on LPS-induced inflammatory response
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1536984
Trace amine associated receptor 1 (TAAR1) expression and modulation of inflammatory cytokine production in mouse bone marrow-derived macrophages: a novel mechanism for inflammation in ulcerative colitis
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1672178
Preclinical evidences of safety of a new synthetic adjuvant to formulate with the influenza human vaccine: absence of subchronic toxicity and mutagenicity
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1566359
Silica nanoparticles as an enhancer in the IL-1β-induced inflammation cycle of A549 cells
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1569046
Identification of discrepancy between CTLA4 expression and CTLA4 activation in gastric cancer
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1533968
Astragaloside inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1637890
Inhibition of interferon-γ production and T-bet expression by menthol treatment of human peripheral blood mononuclear cells
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1588294
T cells expressing CD26-specific chimeric antigen receptors exhibit extensive self-antigen-driven fratricide
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1637889
Anti-inflammatory potential of hecogenin on atopic dermatitis and airway hyper-responsiveness by regulation of pro-inflammatory cytokines
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1608445
Inhibition of fatty acid metabolism by etomoxir or TOFA suppresses murine dendritic cell activation without affecting viability
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1616754
The germ-free mice monocolonization with Bacteroides fragilis improves azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1569047
Polydatin protects against ovalbumin-induced bronchial asthma in rats; involvement of urocortin and surfactant-D expression
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1536985
Pulegone inhibits inflammation via suppression of NLRP3 inflammasome and reducing cytokine production in mice
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1588292
Fumaric acids as a novel antagonist of TLR-4 pathway mitigates arsenic-exposed inflammation in human monocyte-derived dendritic cells
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1645166
Dapsone reduced acetic acid-induced inflammatory response in rat colon tissue through inhibition of NF-kB signaling pathway
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1678635
Phillygenin exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1547742
Fluconazole induces genotoxicity in cultured human peripheral blood mononuclear cells via immunomodulation of TNF-α, IL-6, and IL-10: new challenges for safe therapeutic regimens
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1566357
Meta-analysis on pharmacological therapies in the management of xerostomia in patients with Sjogren’s syndrome
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1593448
Osthole alleviates inflammation by down-regulating NF-κB signaling pathway in traumatic brain injury
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1608560
Protective effect of a topical sunscreen formulation fortified with melatonin against UV-induced photodermatitis: an immunomodulatory effect via NF-κB suppression
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1566358
Apigenin exhibits anti-inflammatory effects in LPS-stimulated BV2 microglia through activating GSK3β/Nrf2 signaling pathway
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1688345
Effects of guluronic acid, as a new NSAID with immunomodulatory properties on IL-17, RORγt, IL-4 and GATA-3 gene expression in rheumatoid arthritis patients
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1702053
Role of angiotensin II type 1 (AT1) and type 2 (AT2) receptors in airway reactivity and inflammation in an allergic mouse model of asthma
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1609026
dl-Malic acid as a component of α-hydroxy acids: effect on 2,4-dinitrochlorobenzene-induced inflammation in atopic dermatitis-like skin lesions in vitro and in vivo
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1680688
Morphine consumption is associated with systemic inflammation in children undergoing allogeneic hematopoietic stem cell transplantation
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1590846
Agmatine ameliorates acetic acid-induced colitis in rats: involvement of nitrergic system
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1578973
Anti-TNF effect of combined pravastatin and cilostazol treatment in an in vivo mouse model
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1569045
In vitro impact of bisphenol A on maturation and function of monocyte-derived dendritic cells in patients with primary Sjögren’s syndrome
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1706554
Hematological and immunological impairment following in-utero and postnatal exposure to aluminum sulfate in female offspring of albino rats
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1533967
Effects of guluronic acid (G2013) on gene expression of TLR2, TLR4, MyD88, TNF-α and CD52 in multiple sclerosis under in vitro conditions
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1672179
The antagonistic effect of tamoxifen against d-galactosamine/lipopolysaccharide-induced acute liver failure is associated with reactivation of hepatic nuclear factor-κB
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1569044
Kaempferol alleviates LPS-ATP mediated inflammatory injury in splenic lymphocytes via regulation of the pyroptosis pathway in mice
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1666405
(3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one enhanced the therapeutic efficacy of anti-PD1 antibody through inhibiting PI3Kδ/γ
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1678634
Modulating effect of a new ester, 28-O-phosphatidylbetulin (DAPB), obtained from hen egg yolk lecithin and betulin on lymphocyte subsets and humoral immune response in mice
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1578972
Survival of lymphocytes is not restricted by IDO-expressing fibroblast from rheumatoid arthritis patients
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1569048
The comparison of bone marrow kinetics between patients with acute myeloid leukemia and acute promyelocytic leukemia after induction chemotherapy
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1692865
Morin inhibits colorectal tumor growth through inhibition of NF-κB signaling pathway
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2019.1688344
A new triple chimeric protein as a high immunogenic antigen against anthrax toxins: theoretical and experimental analyses
来源期刊：Immunopharmacology and ImmunotoxicologyDOI：10.1080/08923973.2018.1510419
