The journal's scope includes understanding the genetic and functional mechanisms that distinguish human individuals in their immune responses to allografts, pregnancy, infections or vaccines as well as the immune responses that lead to autoimmunity, allergy or drug hypersensitivity. It also includes examining the distribution of the genes controlling these responses in populations.Research areas include:Studies of the genetics, genomics, polymorphism, evolution, and population distribution of immune-related genesStudies of the expression, structure and function of the products of immune-related genesImmunogenetics of susceptibility to infectious and autoimmune disease, and allergyThe role of the immune-related genes in hematopoietic stem cell, solid organ, and vascularized composite allograft transplantHistocompatibility studies including alloantibodies, epitope definition, and T cell alloreactivityStudies of immunologic tolerance and pregnancyT cell, B cell, NK and regulatory cell functions, particularly related to subjects within the journal's scopePharmacogenomics and vaccine development in the context of immune-related genesHuman Immunology considers immune-related genes to include those encoding classical and non-classical HLA, KIR, MIC, minor histocompatibility antigens (mHAg), immunoglobulins, TCR, BCR, proteins involved in antigen processing and presentation, complement, Fc receptors, chemokines and cytokines. Other immune-related genes may be considered.Human Immunology is also interested in bioinformatics of immune-related genes and organizational topics impacting laboratory processes, organ allocation, clinical strategies, and registries related to autoimmunity and transplantation.
该杂志的范围包括了解遗传和功能机制，这些机制在人类个体对同种异体移植、妊娠、感染或疫苗的免疫应答以及导致自身免疫、过敏或药物超敏反应的免疫应答中起着区分作用。研究领域包括：免疫相关基因的遗传学、基因组学、多态性、进化和群体分布研究免疫相关基因产物的表达、结构和功能研究感染性疾病、自身免疫性疾病和变态反应的免疫遗传学免疫相关基因在造血干细胞、实体器官和血管化复合同种异体移植中的作用组织相容性研究包括同种抗体、表位定义和T细胞同种反应性免疫耐受和妊娠研究T细胞、B细胞、NK和调节细胞功能，特别是与期刊范围内的主题相关的免疫相关基因的药物基因组学和疫苗开发人类免疫学认为免疫相关基因包括那些编码经典和非经典HLA、KIR、MIC、次要组织相容性抗原（mHAg）、免疫球蛋白、TCR、BCR、参与抗原加工和呈递的蛋白、补体、Fc受体、趋化因子和细胞因子的基因。人类免疫学也对免疫相关基因的生物信息学和影响实验室流程、器官分配、临床策略和自身免疫和移植相关注册的组织主题感兴趣。
Intracellular antigen processing by ERAP2: Molecular mechanism and roles in health and disease.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2018.11.001
Relationship between various cytokines implicated in asthma.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.018
pHLA3D: An online database of predicted three-dimensional structures of HLA molecules
来源期刊：Human ImmunologyDOI：10.1016/J.HUMIMM.2019.06.009
Peptide trimming by endoplasmic reticulum aminopeptidases: Role of MHC class I binding and ERAP dimerization.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.01.003
Exosomes derived from mesenchymal stem cells improved function and survival of neutrophils from severe congenital neutropenia patients in vitro.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.10.006
Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.275
Prevalence of autoimmune diseases and clinical significance of autoantibody profile: Data from National Institute of Hygiene in Rabat, Morocco.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.012
The role of B cell immunity in VCA graft rejection and acceptance.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.03.002
The role of donor-derived exosomes in lung allograft rejection.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.03.012
ERAP1-ERAP2 haplotypes are associated with ankylosing spondylitis in Polish patients.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.004
On the structure-function of MHC class II molecules and how single amino acid polymorphisms could alter intracellular trafficking.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2018.10.001
A role for both HLA-F and HLA-G in reproduction and during pregnancy?
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.09.006
Non-canonical B cell functions in transplantation.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.006
Angiotensin II type I receptor antibodies in thoracic transplantation.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.007
Angiotensin II type I receptor antibodies in pediatric solid organ transplant.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.03.016
HLA-C variants associated with amino acid substitutions in the peptide binding groove influence susceptibility to Kawasaki disease.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.020
Protective association of HLA-DRB1*13:02, HLA-DRB1*04:06, and HLA-DQB1*06:04 alleles with cervical cancer in a Korean population.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2018.10.013
IgM+CD27+ B cells possessed regulatory function and represented the main source of B cell-derived IL-10 in the synovial fluid of osteoarthritis patients.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.007
Clinical relevance of lung-restricted antibodies in lung transplantation.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.016
HLA in Uros from Peru Titikaka Lake: Tiwanaku, Easter and Pacific Islanders.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2018.10.012
Double positive CD4+CD8+ T cells are part of the adaptive immune response against Candida albicans.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.09.008
M1-macrophage polarization is upregulated in deep vein thrombosis and contributes to the upregulation of adhesion molecules.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.05.001
Influence of mode of delivery on cytokine expression in cord blood.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.03.018
Genetic diversity of HLA system in two populations from Yucatán, Mexico: Mérida and rural Yucatán.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.280
A reverse-engineering strategy utilizing the integration of single antigen beads and NGS HLA genotypes to detect potential antibody inducing epitopes.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.002
Genetic diversity of HLA system in two populations from Oaxaca, Mexico: Oaxaca city and rural Oaxaca.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.278
Genetic diversity of HLA system in three populations from Coahuila, Mexico: Torreón, Saltillo and rural Coahuila.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.284
Suitability of dried DNA for long-range PCR amplification and HLA typing by next-generation sequencing.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2018.12.002
Genetic diversity of HLA system in a population from Guerrero, Mexico.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.05.015
Genetic diversity of HLA system in two populations from Quintana Roo, Mexico: Cancún and rural Quintana Roo.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.279
Genetic diversity of HLA system in six populations from Jalisco, Mexico: Guadalajara city, Tlajomulco, Tlaquepaque, Tonalá, Zapopan and rural Jalisco.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.05.012
Strategies for the measurements of expression levels and half-lives of HLA class I allotypes.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.001
Distribution of HLA-DRB1, DPB1 and DQB1 alleles and haplotypes in Mongolian Minority in China.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.01.006
Genetic diversity of HLA system in seven populations from Veracruz, Mexico: Veracruz city, Coatzacoalcos, Córdoba, Orizaba, Poza Rica, Xalapa and rural Veracruz.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.292
Genetic diversity of HLA system in two populations from Puebla, Mexico: Puebla city and rural Puebla.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.290
Genetic diversity of HLA system in two populations from Hidalgo, Mexico: Pachuca and rural Hidalgo.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.293
Deep targeted sequencing reveals the diversity of TRB-CDR3 repertoire in patients with preeclampsia.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.04.003
HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies of 1463 umbilical cord blood units typed in high resolution from Bogotá, Colombia.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.03.006
MicroRNA layer of MHC in infectious diseases.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.006
HLA HHaplotypes In 250 Families: The Baylor Laboratory Results And A Aerspective On A Core NGS Testing Model For The 17th International HLA And Immunogenetics Workshop.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.07.298
5-Locus high-resolution HLA allele and haplotype frequencies in Costa Ricans from the Central Valley.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.05.006
Next generation HLA typing and haplotypes by descent in Gaza individuals.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.11.001
HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 194 Southeast Asia Chinese from Peninsular Malaysia.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.09.005
A survey of known immune epitopes in the enteroviruses strains associated with acute flaccid myelitis.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.08.004
ABO genotyping of various hematopoietic cell lines to select model cells for research purposes.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.08.002
Detection of serum soluble HLA-G levels in patients with acute ischemic stroke: A pilot study.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.11.004
The pattern of HLA-A, -B and -DRB1 alleles and haplotypes of four Malay sub-ethnic groups namely Kelantan, Champa, Patani and Mandailing Malays of Peninsular Malaysia.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.02.015
Allostimulatory activity as a criterion of the functional phenotype of human macrophages.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.08.003
Development of data-driven models for the flow cytometric crossmatch.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.09.004
Particulate poly(methyl methacrylate) could stimulate proinflammatory CD4 T cell responses in a monocyte-dependent manner, and directly mediate cell death.
来源期刊：Human immunologyDOI：10.1016/j.humimm.2019.09.007
