Hereditary Cancer in Clinical Practice is an open access journal that publishes articles of interest for the cancer genetics community and serves as a discussion forum for the development appropriate healthcare strategies.Cancer genetics encompasses a wide variety of disciplines and knowledge in the field is rapidly growing, especially as the amount of information linking genetic differences to inherited cancer predispositions continues expanding. With the increased knowledge of genetic variability and how this relates to cancer risk there is a growing demand not only to disseminate this information into clinical practice but also to enable competent debate concerning how such information is managed and what it implies for patient care.Topics covered by the journal include but are not limited to:Original research articles on any aspect of inherited predispositions to cancer.Reviews of inherited cancer predispositions.Application of molecular and cytogenetic analysis to clinical decision making.Clinical aspects of the management of hereditary cancers.Genetic counselling issues associated with cancer genetics.The role of registries in improving health care of patients with an inherited predisposition to cancer.
《遗传性癌症临床实践》是一本开放获取的期刊，发表癌症遗传学社区感兴趣的文章，并作为制定适当医疗保健策略的讨论论坛。癌症遗传学涵盖了广泛的学科，该领域的知识正在迅速增长，特别是随着将遗传差异与遗传性癌症易感性联系起来的信息量不断扩大。随着对遗传变异性及其与癌症风险的关系的了解的增加，不仅需要将这些信息传播到临床实践中，而且还需要就如何管理这些信息以及这些信息对患者护理的意义进行有效的辩论。该杂志涵盖的主题包括但不限于：关于癌症遗传易感性任何方面的原创研究文章。遗传癌症易感性综述。分子和细胞遗传学分析在临床决策中的应用。遗传癌症管理的临床方面。与癌症遗传学相关的遗传咨询问题。登记在改善癌症遗传易感性患者医疗保健中的作用。
Colorectal carcinoma in the course of inflammatory bowel diseases
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0118-4
Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0106-8
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0111-y
Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0127-3
Increased breast cancer risk in women with neurofibromatosis type 1: a meta-analysis and systematic review of the literature
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0110-z
Spectrum and prevalence of BRCA1/2 germline mutations in Pakistani breast cancer patients: results from a large comprehensive study
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0125-5
BRCA mutation screening and patterns among high-risk Lebanese subjects
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0105-9
Single-center study of Lynch syndrome screening in colorectal polyps
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0108-6
Diagnostic yield and clinical utility of a comprehensive gene panel for hereditary tumor syndromes
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-018-0102-4
The association between non-breast and ovary cancers and BRCA mutation in first- and second-degree relatives of high-risk breast cancer patients: a large-scale study of Koreans
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-018-0103-3
A focused 35-minute whole body MRI screening protocol for patients with von Hippel-Lindau disease
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0121-9
Mutational analysis of BRCA1 and BRCA2 genes in women with familial breast cancer from different regions of Colombia
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0120-x
Age-adjusted association of homologous recombination genes with ovarian cancer using clinical exomes as controls
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0119-3
Examining intrafamilial communication of colorectal cancer risk status to family members and kin responses to colonoscopy: a qualitative study
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0114-8
Implementation of massive sequencing in the genetic diagnosis of hereditary cancer syndromes: diagnostic performance in the Hereditary Cancer Programme of the Valencia Community (FamCan-NGS)
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0104-x
Diagnostic mRNA splicing assay for variants in BRCA1 and BRCA2 identified two novel pathogenic splicing aberrations
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0113-9
Validation of a digital identification tool for individuals at risk for hereditary cancer syndromes
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-018-0099-8
Genetic counselling and personalised risk assessment in the Australian pancreatic cancer screening program
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0129-1
Somatic variants of potential clinical significance in the tumors of BRCA phenocopies
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0117-5
Recommended care and care adherence following a diagnosis of Lynch syndrome: a mixed-methods study
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0130-8
Serum selenium level and cancer risk: a nested case-control study
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0131-7
Prevalence and spectrum of MLH1, MSH2, and MSH6 pathogenic germline variants in Pakistani colorectal cancer patients
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0128-2
Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0116-6
Endometrioid endometrial cancer “recurring” as high-grade serous adenocarcinoma in the inguinal lymph nodes in a patient with germline MLH1 mutated Lynch syndrome: consequence or coincidence?
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0112-x
BRACAVENIR: an observational study of expectations and coping in young women with high hereditary risk of breast and ovarian cancer
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0107-7
Patient-physician relationships, health self-efficacy, and gynecologic cancer screening among women with Lynch syndrome
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0123-7
Patients with pathogenic variants for breast cancer other than BRCA1 and BRCA2: qualitative interviews about health care experiences
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0132-6
Germline c.1A>C heterozygous pathogenic variant in SDHA reported for the first time in a young adult with a gastric gastrointestinal stromal tumour (GIST): a case report
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0124-6
Selected Abstracts from the 3rd European Hereditary Tumour Group Meeting (EHTG 2018)
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0115-7
Outcomes of screening and surveillance in people with two parents affected by colorectal cancers: experiences from the Familial Bowel Cancer Service
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0122-8
A family pedigree of malignancies associated with BRCA1 pathogenic variants: a reflection of the state of art in China
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0126-4
Selected features of breast and peritoneal cancers diagnosed in BRCA1 carriers after risk-reducing salpingo-oophorectomy
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-019-0109-5
Meeting abstracts from the Annual Conference Clinical Genetics of Cancer 2018
来源期刊：Hereditary Cancer in Clinical PracticeDOI：10.1186/s13053-018-0101-5
