Genes & Development publishes high-quality research papers of broad general interest and biological significance in the areas of molecular biology, molecular genetics, and related fields. In addition to Review Articles and Perspectives, Genes & Development publishes three research formats—Research papers, short Research Communications, and Resource/Methodology papers.
《基因与发展》发表高质量的研究论文，涉及分子生物学、分子遗传学和相关领域的广泛兴趣和生物学意义。除了综述文章和观点，基因与发展出版三种研究形式-研究论文，简短的研究通讯，和资源/方法论论文。
Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences.
来源期刊：Genes & developmentDOI：10.1101/gad.331520.119
ZNF445 is a primary regulator of genomic imprinting.
来源期刊：Genes & developmentDOI：10.1101/gad.320069.118
PRC2 is high maintenance.
来源期刊：Genes & developmentDOI：10.1101/gad.325050.119
Host-transposon interactions: conflict, cooperation, and cooption.
来源期刊：Genes & developmentDOI：10.1101/gad.327312.119
Transcription-mediated replication hindrance: a major driver of genome instability.
来源期刊：Genes & developmentDOI：10.1101/gad.324517.119
CD44 splice isoform switching determines breast cancer stem cell state.
来源期刊：Genes & developmentDOI：10.1101/gad.319889.118
Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52.
来源期刊：Genes & developmentDOI：10.1101/gad.324905.119
RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening.
来源期刊：Genes & developmentDOI：10.1101/gad.319723.118
Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer-enhancer interactions.
来源期刊：Genes & developmentDOI：10.1101/gad.322198.118
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
来源期刊：Genes & developmentDOI：10.1101/gad.327056.119
Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells.
来源期刊：Genes & developmentDOI：10.1101/gad.327494.119
Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis.
来源期刊：Genes & developmentDOI：10.1101/gad.320481.118
The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation.
来源期刊：Genes & developmentDOI：10.1101/gad.319590.118
A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair.
来源期刊：Genes & developmentDOI：10.1101/gad.324012.119
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors.
来源期刊：Genes & developmentDOI：10.1101/gad.324715.119
Kidney organoids: accurate models or fortunate accidents.
来源期刊：Genes & developmentDOI：10.1101/gad.329573.119
Molecular regulation of peripheral B cells and their progeny in immunity.
来源期刊：Genes & developmentDOI：10.1101/gad.320192.118
Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis.
来源期刊：Genes & developmentDOI：10.1101/gad.329763.119
Sfp1 regulates transcriptional networks driving cell growth and division through multiple promoter-binding modes.
来源期刊：Genes & developmentDOI：10.1101/gad.322040.118
Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3.
来源期刊：Genes & developmentDOI：10.1101/gad.325100.119
RNAi-dependent Polycomb repression controls transposable elements in Tetrahymena.
来源期刊：Genes & developmentDOI：10.1101/gad.320796.118
Metabolic dependencies and vulnerabilities in leukemia.
来源期刊：Genes & developmentDOI：10.1101/gad.326470.119
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
来源期刊：Genes & developmentDOI：10.1101/gad.328336.119
Epigenetics and transcription regulation during eukaryotic diversification: the saga of TFIID.
来源期刊：Genes & developmentDOI：10.1101/gad.300475.117
Specialization of the Drosophila nuclear export family protein Nxf3 for piRNA precursor export.
来源期刊：Genes & developmentDOI：10.1101/gad.328690.119
Afadin cooperates with Claudin-2 to promote breast cancer metastasis.
来源期刊：Genes & developmentDOI：10.1101/gad.319194.118
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
来源期刊：Genes & developmentDOI：10.1101/gad.314633.118
Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity.
来源期刊：Genes & developmentDOI：10.1101/gad.320077.118
Control of homologous recombination by the HROB-MCM8-MCM9 pathway.
来源期刊：Genes & developmentDOI：10.1101/gad.329508.119
An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion.
来源期刊：Genes & developmentDOI：10.1101/gad.328237.119
The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation.
来源期刊：Genes & developmentDOI：10.1101/gad.322222.118
The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells.
来源期刊：Genes & developmentDOI：10.1101/gad.322024.118
Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination.
来源期刊：Genes & developmentDOI：10.1101/gad.328062.119
Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth.
来源期刊：Genes & developmentDOI：10.1101/gad.331546.119
Resolution of human ribosomal DNA occurs in anaphase, dependent on tankyrase 1, condensin II, and topoisomerase IIα.
来源期刊：Genes & developmentDOI：10.1101/gad.321836.118
Human NORs, comprising rDNA arrays and functionally conserved distal elements, are located within dynamic chromosomal regions.
来源期刊：Genes & developmentDOI：10.1101/gad.331892.119
A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
来源期刊：Genes & developmentDOI：10.1101/gad.320952.118
GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells.
来源期刊：Genes & developmentDOI：10.1101/gad.325696.119
Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6.
来源期刊：Genes & developmentDOI：10.1101/gad.328294.119
Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding.
来源期刊：Genes & developmentDOI：10.1101/gad.324467.119
Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling.
来源期刊：Genes & developmentDOI：10.1101/gad.328971.119
Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination.
来源期刊：Genes & developmentDOI：10.1101/gad.315978.118
Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
来源期刊：Genes & developmentDOI：10.1101/gad.329219.119
Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation.
来源期刊：Genes & developmentDOI：10.1101/gad.321901.118
TRPS1 acts as a context-dependent regulator of mammary epithelial cell growth/differentiation and breast cancer development.
来源期刊：Genes & developmentDOI：10.1101/gad.331371.119
PETISCO is a novel protein complex required for 21U RNA biogenesis and embryonic viability.
来源期刊：Genes & developmentDOI：10.1101/gad.322446.118
Phasing in heterochromatin during development.
来源期刊：Genes & developmentDOI：10.1101/gad.324731.119
A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
来源期刊：Genes & DevelopmentDOI：10.2210/PDB6HOM/PDB
Dosage compensation plans: protein aggregation provides additional insurance against aneuploidy.
来源期刊：Genes & developmentDOI：10.1101/gad.329383.119
Ways to unwind with HROB, a new player in homologous recombination.
来源期刊：Genes & developmentDOI：10.1101/gad.331850.119
