Future Medicinal Chemistry offers a forum for the rapid publication of original research and critical reviews of the latest milestones in the field. Strong emphasis is placed on ensuring that the journal stimulates awareness of issues that are anticipated to play an increasingly central role in influencing the future direction of pharmaceutical chemistry. Where relevant, contributions are also actively encouraged on areas as diverse as biotechnology, enzymology, green chemistry, genomics, immunology, materials science, neglected diseases and orphan drugs, pharmacogenomics, proteomics and toxicology.
未来药物化学提供了一个论坛,为快速发表原创研究和评论的最新里程碑的领域。重点放在确保该杂志激发人们对预期在影响药物化学未来方向方面发挥日益重要作用的问题的认识上。在相关的情况下,还积极鼓励在生物技术、酶学、绿色化学、基因组学、免疫学、材料科学、被忽视的疾病和孤儿药、药物基因组学、蛋白质组学和毒理学等不同领域作出贡献。
Exosome manufacturing status.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0417
The increasing impact of lethal mutagenesis of viruses.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0457
Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0473
Gaseous signaling molecules and their application in resistant cancer treatment: from invisible to visible.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0403
Recent advances of thiazole hybrids in biological applications.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0196
Synthesis, in vitro and in silico studies of HO-1 inducers and lung antifibrotic agents.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0448
State of the art of Smo antagonists for cancer therapy: advances in the target receptor and new ligand structures.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0497
Insights for the design of protein lysine methyltransferase G9a inhibitors.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0396
ADMET profiling of geographically diverse phytochemical using chemoinformatic tools.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0206
Targeting pteridine reductase 1 and dihydrofolate reductase: the old is a new trend for leishmaniasis drug discovery.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0512
Phosphonate prodrugs: an overview and recent advances.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0591
Lights and shadows of electrophile signaling: focus on the Nrf2-Keap1 pathway.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0423
Energy windows for computed compound conformers: covering artefacts or truly large reorganization energies?
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0400
How to replace the lost keys? Strategies toward safer KV7 channel openers.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0350
Glycans in nanomedicine, impact and perspectives.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0368
Foamy matters: an update on Quillaja saponins and their use as immunoadjuvants.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0438
Indole-3-glyoxyl tyrosine: synthesis and antimalarial activity against Plasmodium falciparum.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0246
Sugar ligand-mediated drug delivery.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0114
Can multiscale simulations unravel the function of metallo-enzymes to improve knowledge-based drug discovery?
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0495
Synthesis, anticancer activity, structure-activity relationship and binding mode of interaction studies of substituted pentanoic acids.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0361
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0564
Fluorinated MRI contrast agents and their versatile applications in the biomedical field.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0463
Inactivation of oral biofilms using visible light and water-filtered infrared A radiation and indocyanine green.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0522
Synthesis, characterization and antidiabetic effects of vanadyl(II) adenosine monophosphate amino acid mixed-ligand complexes.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0471
Visnagin and benzofuran scaffold-based molecules as selective cyclooxygenase-2 inhibitors with anti-inflammatory and analgesic properties: design, synthesis and molecular docking.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0398
Targeting uracil-DNA glycosylases for therapeutic outcomes using insights from virus evolution.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0319
Development and strategies of CDK4/6 inhibitors.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0062
Design, synthesis, heme binding and density functional theory studies of isoindoline-dione-4-aminoquinolines as potential antiplasmodials
来源期刊:Future Medicinal ChemistryDOI:10.4155/fmc-2019-0260
Site-specific chemoproteomic profiling of targets of glyoxal.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0221
Inhibiting two cellular mutant epidermal growth factor receptor tyrosine kinases by addressing computationally assessed crystal ligand pockets.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0525
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0535
Synthesis and DNase I inhibitory properties of new benzocyclobutane-2,5-diones.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0032
Rhodamine probes for Fe3+: theoretical calculation for specific recognition and instant fluorescent bioimaging.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0077
The nonepigenetic role for small molecule histone deacetylase inhibitors in the regulation of cardiac function.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0311
Chalcones as a basis for computer-aided drug design: innovative approaches to tackle malaria.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0255
The progresses in curcuminoids-based metal complexes: especially in cancer therapy.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0190
Multifunctional radical quenchers as potential therapeutic agents for the treatment of mitochondrial dysfunction.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0481
Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0290
Synthesis and vasodilator activity of some pyridazin-3(2H)-one based compounds.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0160
Computational insight into the anticholinesterase activities and electronic properties of physostigmine analogs.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0421
Comparison of structures and cytotoxicity of mupirocin and batumin against melanoma and several other cancer cell lines.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0333
New pyrimidines and triazolopyrimidines as antiproliferative and antioxidants with cyclooxygenase-1/2 inhibitory potential.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0285
From biomedicinal to in silico models and back to therapeutics: a review on the advancement of peptidic modeling.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0365
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0022
Design, synthesis and evaluation of belinostat analogs as histone deacetylase inhibitors.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0587
Continuous molecular fields and the concept of molecular co-fields in structure-activity studies.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0360
The synthesis and biological evaluation of a new bioactive metabolite of mosapride as a potential gastroprokinetic agent.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0243
How could histone deacetylase activators be useful leads in the search for new therapeutics?
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0036
Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against Staphylococcus aureus.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2019-0192
Modulation of the coronary tone in the expanding scenario of Chromogranin-A and its derived peptides.
来源期刊:Future medicinal chemistryDOI:10.4155/fmc-2018-0585