The journal evaluates molecules, signalling pathways, receptors and other therapeutic targets and their potential as candidates for drug development. Articles in this journal focus on the molecular level and early preclinical studies. Articles should not include clinical information including specific drugs and clinical trials.The Editors welcome:Reviews covering novel disease targets at the molecular level and information on early preclinical studies and their implications for future drug development.Articles should not include clinical information including specific drugs and clinical trials.Original research papers reporting results of target selection and validation studies and basic mechanism of action studies for investigative and marketed drugs.The audience consists of scientists, managers and decision makers in the pharmaceutical industry, academic researchers working in the field of molecular medicine and others closely involved in R&D.
该杂志评估分子、信号通路、受体和其他治疗靶点及其作为药物开发候选物的潜力。该杂志的文章主要集中在分子水平和早期临床前研究。文章不应包含临床信息，包括特定药物和临床试验。编辑欢迎：涵盖分子水平的新疾病靶点的综述，早期临床前研究的信息及其对未来药物开发的影响。文章不应包含临床信息，包括特定药物和临床试验。报告靶点选择和验证研究结果的原创研究论文，以及研究和上市药物的基本作用机制研究。受众包括制药行业的科学家、管理人员和决策者，分子医学领域的学术研究人员和其他密切参与研发的人员。
Diabetic nephropathy: an insight into molecular mechanisms and emerging therapies
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1624721
The COX-2/prostanoid signaling cascades in seizure disorders
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1554056
The sialoglycan-Siglec glyco-immune checkpoint – a target for improving innate and adaptive anti-cancer immunity
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1667977
Aberrant lipid metabolism as a therapeutic target in liver cancer
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1615883
Targeting toll-like receptor 4 to modulate neuroinflammation in central nervous system disorders
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1676416
Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1586885
Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1586886
Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1570499
Current strategies toward safer mu opioid receptor drugs for pain management
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1586882
Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1602119
Not the comfy chair! Cancer drugs that act against multiple active sites
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1691526
Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1656718
The P2X7 receptor: a new therapeutic target in Alzheimer’s disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1575811
Emerging roles of N- and C-terminally truncated Aβ species in Alzheimer’s disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1702972
The MAP kinase-interacting kinases (MNKs) as targets in oncology
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1571043
An in-depth analysis shows a hidden atherogenic lipoprotein profile in non-diabetic chronic kidney disease patients
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1620206
Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1601703
Genome-wide bioinformatics analysis of FMN, SAM-I, glmS, TPP, lysine, purine, cobalamin, and SAH riboswitches for their applications as allosteric antibacterial drug targets in human pathogenic bacteria
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1618274
Galectin-3: is this member of a large family of multifunctional lectins (already) a therapeutic target?
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1675638
Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2020.1707806
New therapeutics based on emerging concepts in pulmonary fibrosis
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1552262
Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2020.1708326
Poly-ADP-ribose polymerases (PARPs) as a therapeutic target in the treatment of selected cancers
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1654458
Emerging molecular therapeutic targets for spinal cord injury
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1661381
Therapeutic relevance of SOX9 stem cell factor in gastric cancer
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1559826
Pro- and anti-tumorigenic functions of the senescence-associated secretory phenotype
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1565658
The proteasome as a target for protozoan parasites
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1685981
Molecular links between COPD and lung cancer: new targets for drug discovery?
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1615884
Targeting tumor interstitial fluid pressure: will it yield novel successful therapies for solid tumors?
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1702974
E2F1 as a molecular drug target in ovarian cancer
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1579797
Targeting connexin hemichannels to control the inflammasome: the correlation between connexin43 and NLRP3 expression in chronic eye disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1673368
Oncostatin M as a new diagnostic, prognostic and therapeutic target in inflammatory bowel disease (IBD)
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1677608
Inflammation resolution and specialized pro-resolving lipid mediators in CNS diseases
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1691525
The potential of BRAF-associated non-coding RNA as a therapeutic target in melanoma
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1554057
Hepcidin as a therapeutic target for anemia and inflammation associated with chronic kidney disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1599358
Functional genetic evaluation of DNA house-cleaning enzymes in the malaria parasite: dUTPase and Ap4AH are essential in Plasmodium berghei but ITPase and NDH are dispensable
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1575810
Visfatin as a therapeutic target for rheumatoid arthritis
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1617274
Pro-resolving lipid mediators as therapeutic leads for cardiovascular diseases
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1599360
Targeting fundamental aging mechanisms to treat osteoporosis
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1702973
Shedding light on RNaseH: a promising target for hepatitis B virus (HBV)
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1619697
Therapeutic approaches for targeting receptor tyrosine kinase like orphan receptor-1 in cancer cells
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1602608
Agmatine as a potential therapeutic intervention in bipolar depression: the preclinical landscape
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1581764
The potential of dopamine receptor D2 (DRD2) as a therapeutic target for tackling pancreatic cancer
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1606904
Cystic Fibrosis: Proteostatic correctors of CFTR trafficking and alternative therapeutic targets.
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1628948
The farnesoid X receptor: a potential target for expanding the therapeutic arsenal against kidney disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1559825
Rationale for co-targeting CDK4/6 and FGFR pathways in urothelial carcinoma
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1559828
The emergence of Ephexin5 as a therapeutic target in Alzheimer’s disease
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1586884
The importance of targeting HIV reservoirs: preclinical insights on current and potential therapeutic opportunities
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1702971
Fibrinogen-like protein 2: a potential molecular target for glioblastoma treatment
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1628220
Targeting platelet-derived growth factor receptor β inhibits the proliferation and motility of human pterygial fibroblasts
来源期刊：Expert Opinion on Therapeutic TargetsDOI：10.1080/14728222.2019.1653281
