EXCLI Journal publishes original research reports, authoritative reviews and case reports of experimental and clinical sciences.The journal is particularly keen to keep a broad view of science and technology, and therefore welcomes papers which bridge disciplines and may not suit the narrow specialism of other journals. Although the general emphasis is on biological sciences, studies from the following fields are explicitly encouraged (alphabetical order):aging research, behavioral sciences, biochemistry, cell biology, chemistry including analytical chemistry, clinical and preclinical studies, drug development, environmental health, ergonomics, forensic medicine, genetics, hepatology and gastroenterology, immunology, neurosciences, occupational medicine, oncology and cancer research, pharmacology, proteomics, psychiatric research, psychology, systems biology, toxicology
EXCLI Journal发表实验和临床科学的原创研究报告、权威评论和病例报告。该杂志特别热衷于保持科学和技术的广阔视野,因此欢迎跨学科的论文,可能不适合其他期刊的狭窄专业。虽然一般强调生物科学,但明确鼓励以下领域的研究(按字母顺序):衰老研究、行为科学、生物化学、细胞生物学、化学(包括分析化学)、临床和临床前研究、药物开发、环境健康、人体工程学、法医学、遗传学、肝病学和胃肠病学、免疫学、神经科学、职业医学、肿瘤学和癌症研究、药理学、蛋白质组学、精神病学研究、心理学、系统生物学、毒理学
Induction of apoptosis by piperine in human cervical adenocarcinoma via ROS mediated mitochondrial pathway and caspase-3 activation
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1928
Antiviral activity of flavonoids present in aerial parts of Marcetia taxifolia against Hepatitis B virus, Poliovirus, and Herpes Simplex Virus in vitro
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1837
Rhomboid antigens are promising targets in the vaccine development against Toxoplasma gondii
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1993
Up-regulation of long non-coding RNA-PCAT-1 promotes invasion and metastasis in esophageal squamous cell carcinoma
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1847
Cell junctions and oral health
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1370
Physicochemical and cytotoxicity analysis of green synthesis carbon dots for cell imaging
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1465
Senescent HUVECs-secreted exosomes trigger endothelial barrier dysfunction in young endothelial cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1505
Up-regulation of miR-381 inhibits NAD+ salvage pathway and promotes apoptosis in breast cancer cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1431
MCT4 promotes cell proliferation and invasion of castration-resistant prostate cancer PC-3 cell line
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1879
Gene surgery: Potential applications for human diseases
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1833
Classification of chronic myeloid leukemia cell subtypes based on microscopic image analysis
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1292
Macrophage migration inhibitory factor is involved in endovascular trophoblast cell function in vitro
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1630
Effect of glucose and insulin supplementation on the isolation of primary human hepatocytes
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1782
Molecular characteristics and replication mechanism of dengue, zika and chikungunya arboviruses, and their treatments with natural extracts from plants: An updated review
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1825
Long non-coding RNA RPPH1 promotes the proliferation, invasion and migration of human acute myeloid leukemia cells through down-regulating miR-330-5p expression
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1686
Analysis of association of potentially functional genetic variants within genes encoding miR-34b/c, miR-378 and miR-143/145 with prostate cancer in Serbian population
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1257
Deoxynivalenol enhances IL-1ß expression in BV2 microglial cells through activation of the NF-?B pathway and the ASC/NLRP3 inflammasome
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1974
The effects of ovarian cancer cell-derived exosomes on vascular endothelial growth factor expression in endothelial cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1800
In vivo administration of G9a inhibitor A366 decreases osteogenic potential of bone marrow-derived mesenchymal stem cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1234
Interferon-inducible protein (IFI) 16 regulates Chikungunya and Zika virus infection in human skin fibroblasts
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1271
Prostate cancer metastasis and soy isoflavones: a dogfight over a bone
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1836
Molecular diagnosis of glycogen storage disease type I: a review
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1877
Traumatic transnasal penetrating injury with cerebral spinal fluid leak
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1971
Association between four microRNA binding site-related polymorphisms and the risk of warfarin-induced bleeding complications
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1352
The effects of L-carnitine supplementation on glycemic control: a systematic review and meta-analysis of randomized controlled trials
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1447
Association of rs4784227-CASC16 (LOC643714 locus) and rs4782447-ACSF3 polymorphisms and their association with breast cancer risk among Iranian population
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1374
Metformin restores the mitochondrial membrane potentials in association with a reduction in TIMM23 and NDUFS3 in MPP+-induced neurotoxicity in SH-SY5Y cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1703
Nitroxoline: a potent antimicrobial agent against multidrug resistant Enterobacteriaceae
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1378
Osimertinib as treatment for EGFR exon 20 insertion-positive lung adenocarcinoma
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1786
MicroRNA-494 induces breast cancer cell apoptosis and reduces cell viability by inhibition of nicotinamide phosphoribosyltransferase expression and activity
来源期刊:EXCLI JournalDOI:10.17179/excli2018-1748
Neuroprotective mechanism of low-dose sodium nitrite in oxygen-glucose deprivation model of cerebral ischemic stroke in PC12 cells
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1947
Seromolecular assess of Toxoplasma gondii infection in pregnant women and neonatal umbilical cord blood
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1510
Suppressed androgen receptor expression promotes M2 macrophage reprogramming through the STAT3/SOCS3 pathway
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1740
Role of WDR5 in breast cancer prognosis
来源期刊:EXCLI JournalDOI:10.17179/excli2019-2062
The mutational landscape of atypical chronic myeloid leukemia
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1246
Highlight report: Role of choline phospholipid metabolism in tumor progression
来源期刊:EXCLI JournalDOI:10.17179/excli2019-2071
The mTOR kinase inhibitor rapamycin enhances the expression and release of pro-inflammatory cytokine interleukin 6 modulating the activation of human microglial cells
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1715
Human-based dynamics of mental workload in complicated systems
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1372
Successful palliative peptide receptor radionuclide therapy for impending compression of vena cava due to unresectable liver metastasis of neuroendocrine tumor
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1220
Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1098
Crocetin promotes angiogenesis in human endothelial cells through PI3K-Akt-eNOS signaling pathway
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1175
Second exposure to acetaminophen overdose is associated with liver fibrosis in mice
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1920
Association of biofilm formation and cytotoxic potential with multidrug resistance in clinical isolates of Pseudomonas aeruginosa
来源期刊:EXCLI JournalDOI:10.17179/EXCLI2018-1948
Current editorial challenges: Criteria for selecting articles for publication
来源期刊:EXCLI JournalDOI:10.17179/excli2019-2076
Highlight report: Role of PD-L1 in never-smokers
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1516
Implications of the presence of yeasts in tracheobronchial secretions of critically ill intubated patients
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1631
Impaired immunomodulatory ability of type 2 diabetic adipose-derived mesenchymal stem cells in regulation of inflammatory condition in mixed leukocyte reaction
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1575
Trigeminal trophic syndrome: Strange evolution of maxillofacial surgery
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1846
E-selectin as a prognostic factor of patients hospitalized due to acute inflammatory respiratory diseases: a single institutional study
来源期刊:EXCLI JournalDOI:10.17179/excli2019-1624
Tumor suppressor role of genes involved in circadian clock control
来源期刊:EXCLI JournalDOI:10.17179/excli2019-2072