The European Journal of Pharmaceutics and Biopharmaceutics provides a medium for the publication of novel, innovative and hypothesis-driven research from the areas of Pharmaceutics and Biopharmaceutics.Topics covered include for example:Design and development of drug delivery systems for pharmaceuticals and biopharmaceuticals (small molecules, proteins, nucleic acids)Aspects of manufacturing process designBiomedical aspects of drug product designStrategies and formulations for controlled drug transport across biological barriersPhysicochemical aspects of drug product developmentNovel excipients for drug product designDrug delivery and controlled release systems for systemic and local applicationsNanomaterials for therapeutic and diagnostic purposesAdvanced therapy medicinal productsMedical devices supporting a distinct pharmacological effect.
《欧洲药剂学和生物药剂学杂志》为药剂学和生物药剂学领域的新的、创新的和假设驱动的研究提供了一个出版媒介。所涵盖的主题包括例如：药物和生物药剂（小分子、蛋白质、核酸）的药物递送系统的设计和开发生产工艺设计方面药物产品设计的生物医学方面控制药物跨生物屏障转运的策略和配方药物产品开发的物理化学方面药物产品设计的新型赋形剂用于全身和局部应用的药物递送和控释系统用于治疗和诊断目的的纳米材料先进的治疗药物产品支持独特药理作用的医疗器械。
Cubosomes for topical delivery of the antimicrobial peptide LL‐37
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.009
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.12.010
Recent advances in microneedle‐based drug delivery: Special emphasis on its use in paediatric population
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.005
Hyaluronic acid functionalized nanoparticles loaded with IR780 and DOX for cancer chemo‐photothermal therapy
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.016
Human primary macrophages scavenge AuNPs and eliminate it through exosomes. A natural shuttling for nanomaterials
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.014
Hyaluronan‐based dissolving microneedles with high antigen content for intradermal vaccination: Formulation, physicochemical characterization and immunogenicity assessment
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.013
Lipodendriplexes: A promising nanocarrier for enhanced gene delivery with minimal cytotoxicity
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.12.013
3D printed, controlled release, tritherapeutic tablet matrix for advanced anti‐HIV‐1 drug delivery
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.04.007
Efficacy of a novel LyP‐1‐containing self‐microemulsifying drug delivery system (SMEDDS) for active targeting to breast cancer
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.017
Development of a flow‐through USP 4 apparatus drug release assay for the evaluation of amphotericin B liposome
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.010
Solid lipid nanoparticles for the delivery of anti‐microbial oligonucleotides
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.017
Towards a Maraviroc long‐acting injectable nanoformulation
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.04.009
Lipid gene nanocarriers for the treatment of skin diseases: Current state‐of‐the‐art
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.012
Edible solid foams as porous substrates for inkjet‐printable pharmaceuticals
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.004
Stimulus‐responsive nanoscale delivery systems triggered by the enzymes in the tumor microenvironment
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.009
Nano spray dried antibacterial coatings for dental implants
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.003
Biophysical interaction of temozolomide and its active metabolite with biomembrane models: The relevance of drug‐membrane interaction for Glioblastoma Multiforme therapy
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.015
Modeling, design and manufacture of innovative floating gastroretentive drug delivery systems based on hot‐melt extruded tubes
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.022
Potential therapeutic effect of curcumin loaded hyalurosomes against inflammatory and oxidative processes involved in the pathogenesis of rheumatoid arthritis: The use of fibroblast‐like synovial cells cultured in synovial fluid
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.012
Pharmacological characterization of the 3D MucilAir™ nasal model
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.04.002
Development of resiquimod‐loaded modified PLA‐based nanoparticles for cancer immunotherapy: A kinetic study
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.04.007
Vaccination with influenza hemagglutinin‐loaded ceramic nanoporous microneedle arrays induces protective immune responses
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.002
Mechanistic analysis and experimental verification of bicarbonate‐controlled enteric coat dissolution: Potential in vivo implications
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.012
Insight into imiquimod skin permeation and increased delivery using microneedle pre‐treatment
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.006
Characterization of the GI transit conditions in Beagle dogs with a telemetric motility capsule
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.026
N‐glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.018
Increasing the percutaneous absorption and follicular penetration of retinal by topical application of proretinal nanoparticles
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.014
Ultrafast in situ forming poly(ethylene glycol)‐poly(amido amine) hydrogels with tunable drug release properties via controllable degradation rates
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.04.006
Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2‐expressing tumours
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.004
Evaluation of chemometric approaches for polymorphs quantification in tablets using near‐infrared hyperspectral images
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.007
Lipid nanocapsules decorated and loaded with cannabidiol as targeted prolonged release carriers for glioma therapy: In vitro screening of critical parameters
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.020
Imiquimod‐loaded nanocapsules improve cytotoxicity in cervical cancer cell line
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.001
Sortagging of liposomes with a murine CD11b‐specific VHH increases in vitro and in vivo targeting specificity of myeloid cells
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.014
Targeted brain delivery of methotrexate by glutathione PEGylated liposomes: How can the formulation make a difference?
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.04.004
Physiologically based absorption modeling to predict bioequivalence of controlled release and immediate release oral products
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.019
Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP‐001
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.012
Hydroxycamptothecin nanoparticles based on poly/oligo (ethylene glycol): Architecture effects of nanocarriers on antitumor efficacy
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.12.003
Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.04.005
Optimisation of an in‐line Raman spectroscopic method for continuous API quantification during twin‐screw wet granulation and its application for process characterisation
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.015
Evaluation of the effects of spray drying parameters for producing cubosome powder precursors
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.12.008
Ultra–fast disintegrating ODTs comprising viable probiotic bacteria and HPMC as a mucoadhesive
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.022
Covalently binding mucoadhesive polymers: N‐hydroxysuccinimide grafted polyacrylates
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.02.017
Tumor recognition of peanut agglutinin‐immobilized fluorescent nanospheres in biopsied human tissues
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.007
Conversion of PLGA nanoparticle suspensions into solid dosage forms via fluid bed granulation and tableting
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2018.11.011
Oral coadministration of elacridar and ritonavir enhances brain accumulation and oral availability of the novel ALK/ROS1 inhibitor lorlatinib
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.016
QobuR – A new in vitro human corneal epithelial model for preclinical drug screening
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.01.023
Effect of particle deposition density of dry powders on the results produced by an in vitro test system simulating dissolution‐ and absorption rates in the lungs
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.005
Evaluation of the suitability of a fluidized bed process for the coating of drug‐eluting stents
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.013
Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.11.005
SOFTs – Structured orodispersible film templates
来源期刊：European Journal of Pharmaceutics and BiopharmaceuticsDOI：10.1016/j.ejpb.2019.03.001
