The journal publishes in the areas of toxicity and toxicology of environmental pollutants in air, dust, sediment, soil and water, and natural toxins in the environment.Of particular interest are:Toxic or biologically disruptive impacts of anthropogenic chemicals such as pharmaceuticals, industrial organics, agricultural chemicals, and by-products such as chlorinated compounds from water disinfection and waste incineration;Natural toxins and their impacts;Biotransformation and metabolism of toxigenic compounds, food chains for toxin accumulation or biodegradation;Assays of toxicity, endocrine disruption, mutagenicity, carcinogenicity, ecosystem impact and health hazard;Environmental and public health risk assessment, environmental guidelines, environmental policy for toxicants.
该杂志发表的内容涉及空气、灰尘、沉积物、土壤和水中环境污染物的毒性和毒理学以及环境中的天然毒素。特别感兴趣的是：人为化学品的毒性或生物破坏性影响，如药物、工业有机物、农业化学品和副产品，如水消毒和废物焚烧产生的氯化化合物;自然毒素及其影响;产毒化合物的生物转化和代谢，毒素积累或生物降解的食物链;毒性、内分泌干扰、致突变性、致癌性、生态系统影响和健康危害试验;环境和公共健康风险评估、环境指南、有毒物质环境政策。
Expression of pro‐inflammatory cytokines and mediators induced by Bisphenol A via ERK‐NFκB and JAK1/2‐STAT3 pathways in macrophages
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22702
Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress‐induced toxicity by miR‐181/SIRT1/PGC‐1α/Nrf2 signaling pathway in human neuroblastoma SH‐SY5Y cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22736
Ursolic acid induces apoptosis and autophagy in oral cancer cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22769
State of the science review of the health effects of inorganic arsenic: Perspectives for future research
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22673
Perfluorooctanoic acid disrupts gap junction intercellular communication and induces reactive oxygen species formation and apoptosis in mouse ovaries
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22661
Chemopreventive efficacy zingerone (4‐[4‐hydroxy‐3‐methylphenyl] butan‐2‐one) in experimental colon carcinogenesis in Wistar rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22727
Embryonic development, locomotor behavior, biochemical, and epigenetic effects of the pharmaceutical drugs paracetamol and ciprofloxacin in larvae and embryos of Danio rerio when exposed to environmental realistic levels of both drugs
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22819
Ameliorative effects of vitamin B17 on the kidney against Ehrlich ascites carcinoma induced renal toxicity in mice
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22888
Regorefenib induces extrinsic/intrinsic apoptosis and inhibits MAPK/NF‐κB‐modulated tumor progression in bladder cancer in vitro and in vivo
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22734
Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis, and DNA damage against oral cancer cells through oxidative stress
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22748
Modulatory effects of Saussurea lappa root aqueous extract against ethephon‐induced kidney toxicity in male rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22828
Di (2‐ethylhexyl) phthalate targets the thioredoxin system and the oxidative branch of the pentose phosphate pathway in liver of Balb/c mice
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22844
Effects of polystyrene microbeads on cytotoxicity and transcriptomic profiles in human Caco‐2 cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22885
Aberrant methylation‐induced dysfunction of p16 is associated with osteoblast activation caused by fluoride
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22655
Vitamin D protects against particles‐caused lung injury through induction of autophagy in an Nrf2‐dependent manner
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22726
LncRNA‐Jak3:Jak3 coexpressed pattern regulates monosodium urate crystal‐induced osteoclast differentiation through Nfatc1/Ctsk expression
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22672
Molecular cloning and characterization of two ARNT (ARNT‐1 and ARNT‐2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22670
Analysis of long non‐coding RNA involved in atrazine‐induced testicular degeneration of Xenopus laevis
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22704
Chronic exposure to dichloroacetamide induces biochemical and histopathological changes in the gills of zebrafish
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22744
Bergapten induces G1 arrest and pro‐apoptotic cascade in colorectal cancer cells associating with p53/p21/PTEN axis
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22685
Long‐term exposure to extremely low‐dose of nicotine and 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) induce non‐malignant breast epithelial cell transformation through activation of the a9‐nicotinic acetylcholine receptor‐mediated signaling pathway
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22659
Epimagnolin A inhibits IL‐6 production by inhibiting p38/NF‐κB and AP‐1 signaling pathways in PMA‐stimulated THP‐1 cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22746
The mechanism of damage by trace amounts of acetamiprid to the midgut of the silkworm, Bombyx mori
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22775
Reduced camptothecin sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di(2‐ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22694
Exposure to cigarette smoke via respiratory system may induce abnormal alterations of reproductive organs in female diabetic rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22652
Oxidative stress and neuromodulatory effects of deltamethrin and its combination with insect repellents in rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22741
Phytol ameliorated benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice via inhibition of oxidative stress and apoptosis
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22690
Overexpression of IGF‐IIRα regulates cardiac remodeling and aggravates high salt induced apoptosis and fibrosis in transgenic rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22676
Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22773
Oxidative stress, immunological response, and heat shock proteins induction in the Chinese Mitten Crab, Eriocheir sinensis following avermectin exposure
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22858
The sonic hedgehog signaling pathway is suppressed following PCB1254 exposure during retinal development
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22689
Effects of soluble copper and copper oxide nanoparticle exposure on the immune system of mussels, Mytilus galloprovincialis
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22684
Potential benefits of polysaccharides derived from marine alga Ulva lactuca against hepatotoxicity and nephrotoxicity induced by thiacloprid, an insecticide pollutant
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22818
Taiwanin C elicits apoptosis in arecoline and 4‐nitroquinoline‐1‐oxide‐induced oral squamous cell carcinoma cells and hinders proliferation via epidermal growth factor receptor/PI3K suppression
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22742
Exploring the impact of a naturally occurring sapogenin diosgenin on underlying mechanisms of Ca2+ movement and cytotoxicity in human prostate cancer cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22876
Transcriptomic analyses of human bronchial epithelial cells BEAS‐2B exposed to brominated flame retardant (tetrabromobisphenol A)
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22740
Xanthohumol protects against Azoxymethane‐induced colorectal cancer in Sprague‐Dawley rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22849
Inhaled Kathon may induce eosinophilia‐mediated disease in the lung
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22839
Effects of phenanthrene on oxidative stress and inflammation in lung and liver of female rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22840
Benzyl isothiocyanate promotes miR‐99a expression through ERK/AP‐1‐dependent pathway in bladder cancer cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22841
Human albumin augmented airway inflammation induced by PM2.5 in NC/Nga mice
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22751
Assessment of impact of α‐Fe2O3 and γ‐Fe2O3 nanoparticles on phytoplankton species Selenastrum capricornutum and Nannochloropsis oculata
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22875
Toxic effects of hydrogen sulfide donor NaHS induced liver apoptosis is regulated by complex IV subunits and reactive oxygen species generation in rats
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22868
Dust induces lung fibrosis through dysregulated DNA methylation
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22739
Gas chromatography‐mass spectrometry based metabolomics profile of hippocampus and cerebellum in mice after chronic arsenic exposure
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22662
Aryl hydrocarbon receptor signaling, toxicity, and gene expression responses to mono‐methylchrysenes
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22770
Effects of environmental chemicals on the proliferation and differentiation of neural stem cells
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22829
Protective effects of trehalose against Mn‐induced α‐synuclein oligomerization in mice: Involvement of oxidative stress and autophagy
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22842
PM2.5 upregulates rat mesenteric arteries 5‐HT2A receptor via inflammatory‐mediated mitogen‐activated protein kinases signaling pathway
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22810
Combining proteomics and lipid analysis to unravel Confidor stress response in Saccharomyces cerevisiae
来源期刊：Environmental ToxicologyDOI：10.1002/tox.22870
