Drug and Chemical Toxicology publishes full-length research papers, review articles and short communications that encompass a broad spectrum of toxicological data surrounding risk assessment and harmful exposure. Manuscripts are considered according to their relevance to the journal. Topics include both descriptive and mechanics research that illustrates the risk assessment implications of exposure to toxic agents. Examples of suitable topics include toxicological studies, which are structural examinations on the effects of dose, metabolism, and statistical or mechanism-based approaches to risk assessment. New findings and methods, along with safety evaluations, are also acceptable. Special issues may be reserved to publish symposium summaries, reviews in toxicology, and overviews of the practical interpretation and application of toxicological data.
《药物和化学毒理学》出版了完整的研究论文、综述文章和简短的通讯，涵盖了围绕风险评估和有害暴露的广泛毒理学数据。稿件根据其与期刊的相关性进行考虑。主题包括描述性和力学研究，说明暴露于有毒物质的风险评估影响。合适的主题包括毒理学研究，即对剂量、代谢和统计学或基于机制的风险评估方法的影响进行结构检查。新的发现和方法沿着安全性评价也是可以接受的。特刊可保留用于发表专题讨论会摘要、毒理学综述以及毒理学数据的实际解释和应用概述。
Toxicity evaluation of magnetic iron oxide nanoparticles reveals neuronal loss in chicken embryo
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2017.1413110
Cytotoxicity of acetylcholinesterase reactivators evaluated in vitro and its relation to their structure
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1432641
Potential of curcumin and resveratrol as biochemical and biophysical modulators during lung cancer in rats
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1523921
Beneficial effects of Urtica dioica on scopolamine-induced memory impairment in rats: protection against acetylcholinesterase activity and neuronal oxidative damage
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1463238
Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1586916
In vitro comparative cytotoxicity study of aminated polystyrene, zinc oxide and silver nanoparticles on a cervical cancer cell line
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1424181
Influence of some β-lactam drugs on selected antioxidant enzyme and lipid peroxidation levels in different rat tissues
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2019.1608230
Protective effect of aminoguanidine against lipopolysaccharide-induced hepatotoxicity and liver dysfunction in rat
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1561712
Neurophysiological responses in the brain tissues of rainbow trout (Oncorhynchus mykiss) treated with bio-pesticide
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1526180
Assessment of acetamiprid-induced genotoxic effects in bone marrow cells of Swiss albino male mice
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1429461
The protective effect of Zataria multiflora Boiss essential oil on CCl4 induced liver fibrosis in rats.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1571502
Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1573825
Characterization and toxicology evaluation of zirconium oxide nanoparticles on the embryonic development of zebrafish, Danio rerio
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1523186
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2017.1413108
Induction of chromosomal and DNA damage and histological alterations by graphene oxide nanoparticles in Swiss mice.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1643876
Biogenic synthesis and characterization of silver nanoparticles using aqueous leaf extract of Scoparia dulcis L. and assessment of their antimicrobial property
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1505903
In vivo toxicity evaluation of nanoemulsions for drug delivery.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1659806
Nano titanium exposure induces dose- and size-dependent cytotoxicity on human epithelial lung and colon cells
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1452930
Evaluation of in vitro and in vivo genotoxic and antigenotoxic effects of Rhus coriaria.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1593433
Evaluation of the anti-oxidant and anti-inflammatory effects of the methanolic extract of Ferula szowitsiana root on PHA-induced inflammation in human lymphocytes
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2019.1572182
Anti-inflammatory, anti-oxidant and hepatoprotective effects of lactoferrin in rats.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1585868
Cucurbitacin E glucoside from Citrullus colocynthis inhibits testosterone-induced benign prostatic hyperplasia in mice.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1635149
Effects of dechlorane plus on oxidative stress, inflammatory response, and cell apoptosis in Cyprinus carpio.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1701001
Agomelatine protects heart and aorta against lipopolysaccharide-induced cardiovascular toxicity via inhibition of NF-kβ phosphorylation.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1663209
Long-term consumption of alcohol exacerbates neural lesions by destroying the functional integrity of the blood-brain barrier.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1681444
Phytochemical and toxicological evaluation of Tamarix stricta Boiss.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1680687
In vitro cytotoxicity of polyphenols from Datura innoxia aqueous leaf-extract on human leukemia K562 cells: DNA and nuclear proteins as targets
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2019.1629588
Protective effects of diarylpropionitrile against hydrogen peroxide-induced damage in human neuroblastoma SH-SY5Y cells.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1658768
Cytotoxicity and genotoxicity of clothianidin in human lymphocytes with or without metabolic activation system
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1438458
Co-exposure to nTiO2 impairs arsenic metabolism and affects antioxidant capacity in the marine shrimp Litopenaeus vannamei
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1563610
Caffeine attenuates seizure and brain mitochondrial disruption induced by Tramadol: the role of adenosinergic pathway.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1643874
An electrochemical sensor for the determination of tartrazine based on CHIT/GO/MWCNTs/AuNPs composite film modified glassy carbon electrode.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1601210
Oxidative damage to membrane lipids in the thyroid - no differences between sexes.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1643878
A new active peptide from Neptunea arthritica cumingii exerts protective effects against gentamicin-induced sensory-hair cell injury in zebrafish.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1665680
Interaction of cigarette smoke condensate and some of its components with chlorpromazine toxicity on Saccharomyces cerevisiae.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1659809
Subclinical nephrotoxicity in patients with beta-thalassemia: role of urinary kidney injury molecule.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1660362
Safety assessment of MEFAS: an innovative hybrid salt of mefloquine and artesunate for malaria treatment.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1607371
Illuminating the cellular and molecular mechanism of the potential toxicity of methacrylate monomers used in biomaterials
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1488860
Oral administration of a potassium bromate dosage: Determination and evaluation of accumulated bromate on the liver of male mice.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1662435
Toxicological evaluation of ergocalciferol, cholecalciferol, and their metabolites by a category approach.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1650061
Protective effects of ethyl acetate extracts of Rimulus Cinnamon on systemic inflammation and lung injury in endotoxin-poisoned mice
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1509987
Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2019.1585869
Protective effect of Coleus forskohlii leaf-extract compound on progression of cataract against Fructose-Induced experimental cataract in rats.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1668404
Orlistat increases arsenite tolerance in THP-1 derived macrophages through the up-regulation of ABCA1.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1683571
Evaluation of the acute and 28-day sub-acute intravenous toxicity of α-l-guluronic acid (ALG; G2013) in mice.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1665679
Studies on oral subacute toxicity of cartap in male mice
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2018.1551900
Salusin-α mitigates diabetic nephropathy via inhibition of the Akt/mTORC1/p70S6K signaling pathway in diabetic rats.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1683572
Comparing the effects of Portulaca oleracea seed hydro-alcoholic extract, valsartan, and vitamin E on hemodynamic changes, oxidative stress parameters and cardiac hypertrophy in thyrotoxic rats.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1651330
Evaluation of cell protection by Psephellus pyrrhoblepharus (Boiss.) Wagenitz extracts in MPP+-induced dopaminergic cell damage.
来源期刊：Drug and chemical toxicologyDOI：10.1080/01480545.2019.1659808
Whole body exposure of rats to sulfur mustard vapor
来源期刊：Drug and Chemical ToxicologyDOI：10.1080/01480545.2017.1402917
