The journal brings readers the latest developments in the fast moving field of cellular therapy in man. This includes cell therapy for cancer, immune disorders, inherited diseases, tissue repair and regenerative medicine. The journal covers the science, translational development and treatment with variety of cell types including hematopoietic stem cells, immune cells (dendritic cells, NK, cells, T cells, antigen presenting cells) mesenchymal stromal cells, adipose cells, nerve, muscle, vascular and endothelial cells, and induced pluripotential stem cells. We also welcome manuscripts on subcellular derivatives such as exosomes. A specific focus is on translational research that brings cell therapy to the clinic. Cytotherapy publishes original papers, reviews, position papers editorials, commentaries and letters to the editor. We welcome "Protocols in Cytotherapy" bringing standard operating procedure for production specific cell types for clinical use within the reach of the readership.
该杂志为读者带来快速发展的人体细胞治疗领域的最新进展。这包括癌症、免疫紊乱、遗传性疾病、组织修复和再生医学的细胞疗法。该杂志涵盖了各种细胞类型的科学、转化开发和治疗,包括造血干细胞、免疫细胞(树突细胞、NK细胞、T细胞、抗原呈递细胞)间充质基质细胞、脂肪细胞、神经、肌肉、血管和内皮细胞和诱导多能干细胞。我们也欢迎关于外泌体等亚细胞衍生物的手稿。特别关注将细胞疗法带入临床的转化研究。 Cytotherapy出版原创论文、评论、立场文件社论、评论和致编辑的信件。我们欢迎“Protocols in Cytotherapy”为读者带来临床使用的生产特定细胞类型的标准操作程序。
Mesenchymal stem versus stromal cells: International Society for Cellular Therapy Mesenchymal Stromal Cell committee position statement on nomenclature.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.08.002
Bone marrow-derived mesenchymal stromal cells ameliorate severe acute pancreatitis in rats via hemeoxygenase-1-mediated anti-oxidant and anti-inflammatory effects.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2018.11.013
Levels of IL-17F and IL-33 correlate with HLA-DR activation in clinical-grade human bone marrow-derived multipotent mesenchymal stromal cell expansion cultures.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2018.09.009
Preservation of cell-based immunotherapies for clinical trials.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.07.004
CD19 chimeric antigen receptor (CAR) engineered epstein-barr virus (EBV) specific T cells – an off-the-shelf, allogeneic CAR T-cell immunotherapy platform
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.569
Optimization of manufacturing conditions for chimeric antigen receptor T cells to favor cells with a central memory phenotype.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.03.003
Medulloblastoma rendered susceptible to NK-cell attack by TGFß neutralization
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.337
Enrichment of vascular endothelial growth factor secreting mesenchymal stromal cells enhances therapeutic angiogenesis in a mouse model of hind limb ischemia.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2018.12.007
Gamma irradiation of human platelet lysate: validation of efficacy for pathogen reduction and assessment of impacts on hpl performance
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.498
Autologous cryopreserved leukapheresis cellular material for chimeric antigen receptor-T cell manufacture.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.10.005
NK92-CD16 cells are cytotoxic to non-small cell lung cancer cell lines that have acquired resistance to tyrosine kinase inhibitors.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.03.312
Human CD141+ dendritic cells generated from adult peripheral blood monocytes.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.07.007
Scaling a xeno-free fed-batch microcarrier suspension bioreactor system from development to production scale for manufacturing XF hMSCs
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.464
Tangential flow filtration, a potential method for the scaled preparation of extracellular vesicles
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.431
Volume-by-volume bioprinting of chondrocytes-alginate bioinks in high temperature thermoplastic scaffolds for cartilage regeneration
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.326
Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.322
Cellular mechanism in support of allogenic human amnion epithelial cell transplantation without immunosuppression
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.335
Validation of a semi automatic device to standardize quantification of Colony-Forming Unit (CFU) on hematopoietic stem cell products.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.06.005
A single dose of donor lymphocytes depleted of anti-host reactive T cells (ATIR101) following T-cell-depleted haploidentical HSCT is safe and efficaceous
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.319
Molecular profiles of functionally effective MSC-Derived extracellular vesicles in immunomodulation
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.011
Scalable, robust and cost effective CAR-T manufacturing
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.390
Effect of bone marrow mesenchymal stromal cells and conditioned medium in an irreversible unilateral ureteral obstruction murine model.
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.462
Establishing the ethical and regulatory frame work for a clinically compliant ipsc cell line bank; from qa to donor reconsent.
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.043
Microfluidic purification of T lymphocytes separated from blood for chimeric antigen receptor T-cell manufacturing
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.013
Optimizing cryopreservation of hematopoietic stem cells collected for autologous stem cell transplantation in patients with multiple myeloma
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.375
Evaluation of serum-free media formulations in feeder cell expansion of natural killer cells
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.353
Evaluation of human platelet lysate (HPL) as a substitute for foetal bovine serum (FBS) and recombinant proteins for the growth and maintenance of bone marrow derived mesenchymal stromal cells (BM-MSC)
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.505
Phase I dose escalating trail of GPC3-targeted CAR-T cells by intratumor injection for Advanced Hepatocellular carcinoma
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.566
Impact of CAR T-cell product viability on B-cell lymphoid malignancy outcomes
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.316
Efficacies of stem cell therapies for functional improvement of the β cell in patients with diabetes: A systematic review of controlled clinical trials.
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.410
Stem cells from follicular fluid present multilineage differentiation capacity and form oocyte-like structures under the influence of FSH hormone
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.481
Validation of circulating CD34+ cell counts as criteria for initiating peripheral blood stem cell collection in pediatric patients
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.447
Targeting adeno-associated viral vectors to fractures and the skeleton
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.008
A novel combination cell therapy using first trimester human umbilical cord-derived mesenchymal stromal cells and endothelial progenitor cells significantly improves cardiac recovery after myocardial infarction
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.455
Applicable possibility of autologous osteochondral regenerative medicine using umbilical cord-derived mesenchymal stromal cells of cleft palate patient
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.488
Reducing the dependency of operator-based counting methods during the manufacturing process of cell and gene therapies.
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.528
Arthroscopic evidence of cartilage regeneration in severe knee cartilage defects and osteoarthritis following treatment with allogeneic umbilical cord-derived mesenchymal stromal cells (Chondrocell-Ex)
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.517
Stepwise methodology for processing marrow products from matched siblings for possible T-cell depletion in patients with fanconi anemia
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.458
CD34+ stromal vascular fraction was instrumental in mediating hepatic repair regarding gene expression profiles
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.030
Achieving therapeutic efficacy with a high performance, electroporation-based cellular engineering technology
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.049
Selective local irradiation improves islet engraftment and survival in intra-bone marrow islet transplantation.
来源期刊:CytotherapyDOI:10.1016/j.jcyt.2019.07.005
A novel flow cytometry-based method to characterize transfection efficiency in genetically engineered mesenchymal stem cells
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.041
Identification and quantification of immune cell types using PCR-based PureQuant methylation assay
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.343
Development of a novel bioreactor platform for CAR T-Cells expansion
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.389
Establishing iPSC cell banks derived using reagents and workflows optimized for cell therapy manufacturing
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.574
Culture enhanced mesenchymal stromal cells with increased potency
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.532
Optimization of a phenol red-free T cell expansion medium to improve performance and workflow flexibility
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.04.047
A promising blood-derived novel treatment for critical limb ischemia and beyond
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.314
Factors predicting peripheral blood stem cell (PBSC) mobilization with plerixafor in multiple myeloma patients who had inadequate mobilization with G-CSF.
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.438
Early reno-protective antioxidant activity of bone marrow-derived mesenchymal stem cells single dose in renal ischemia-reperfusion in rats
来源期刊:CytotherapyDOI:10.1016/J.JCYT.2019.03.465