Current Opinion in Pharmacology (COPHAR) publishes authoritative, comprehensive, and systematic reviews. COPHAR helps specialists keep up to date with a clear and readable synthesis on current advances in pharmacology and drug discovery. Expert authors annotate the most interesting papers from the expanding volume of information published today, saving valuable time and giving the reader insight on areas of importance.
《药理学最新观点》(COPHAR)发表权威、全面和系统的综述。COPHAR帮助专家保持最新的清晰和可读的综合在药理学和药物发现的最新进展。专家作者从今天出版的不断增加的信息量中注释最有趣的论文,节省了宝贵的时间,并让读者对重要领域有深刻的见解。
The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.011
Flavonoids in hypertension: a brief review of the underlying mechanisms.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.014
The future of peptides in cancer treatment.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.01.008
New and emerging anti-fibrotic therapeutics entering or already in clinical trials in chronic liver diseases.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.006
Novel biologics targeting the P2X7 ion channel.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.001
Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.08.004
Recent advances of anti-cancer therapies including the use of cell-penetrating peptides.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.01.003
P2X4 and lysosome fusion.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.002
Pharmacological development in hidradenitis suppurativa.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.006
State of the art and pharmacological pipeline of biologics for chronic plaque psoriasis.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.05.007
Pharmacological advances in pemphigoid.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.12.007
Modern sun protection.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.12.006
Trends in the treatment and prevention of keratinocyte carcinoma (non-melanoma skin cancer).
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.12.002
The race between drug introduction and appearance of microbial resistance. Current balance and alternative approaches.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.016
Mucosal IgE immune responses in respiratory diseases.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.05.009
The NIH microphysiological systems program: developing in vitro tools for safety and efficacy in drug development.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.007
Targeting P2X4 and P2X7 receptors in multiple sclerosis.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.010
The de-Alzheimerization of age-related dementias: implications for drug targets and approaches to effective therapeutics.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.01.004
Clinical effectiveness of novel rosacea therapies.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.12.001
Recent findings of molecules with anti-infective activity: screening of non-conventional sources.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.003
Impaired cross-talk between NO and hyperpolarization in myoendothelial feedback: a novel therapeutic target in early endothelial dysfunction of metabolic disease.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.007
Clinical trials of prion disease therapeutics.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.019
Purinergic receptors and the inflammatory response mediated by lipids.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.02.004
Autoimmunity in microbiome-mediated diseases and novel therapeutic approaches.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.018
The gut microbiome and pharmacology: a prescription for therapeutic targeting of the gut-brain axis.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.007
Fecal microbiota transplantation donation: the gift that keeps on giving.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.04.009
Microfluidics for personalized drug screening of cancer.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.008
The role of the P2X7 receptor in myeloid-derived suppressor cells and immunosuppression.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.02.010
Pharmacological advances in pemphigus.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.01.001
Pharmacological strategies for targeting platelet activation in asthma.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.012
Therapeutic strategies for eosinophilic dermatoses.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.01.002
Untangling human neurogenesis to understand and counteract brain disorders.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.12.002
NG2 cells and their neurogenic potential.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.11.005
Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy
来源期刊:Current Opinion in PharmacologyDOI:10.1016/j.coph.2019.10.004
P2X7 purinoceptor as a therapeutic target in muscular dystrophies.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.02.003
Agonist-evoked endothelial Ca2+ signalling microdomains.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.03.005
Peptides in clinical development for the treatment of brain tumors.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.02.007
Pathology and natural history of organ fibrosis.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.009
Understanding the effects of air pollution on neurogenesis and gliogenesis in the growing and adult brain.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.12.003
Unravelling fibrosis using single-cell transcriptomics.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.004
Role of the purinergic P2X receptors in osteoclast pathophysiology.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.02.013
Bacterial peptidoglycans as novel signaling molecules from microbiota to brain.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.08.003
Bacterial cross-resistance to anti-infective compounds. Is it a real problem?
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.05.004
Identification of anti-prion drugs and targets using toxicity-based assays.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.12.005
Ependymal cells in the spinal cord as neuronal progenitors.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.11.008
Rhythm on a chip: circadian entrainment in vitro is the next frontier in body-on-a chip technology.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.09.005
Transcription inhibitors and inflammatory cell activity.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.05.006
Nutrients and neurogenesis: the emerging role of autophagy and gut microbiota.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.11.004
Advances in the epigenetics of fibroblast biology and fibrotic diseases.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2019.10.001
More than cell wall hydrolysis: orchestration of cellular dynamics for organ separation.
来源期刊:Current opinion in pharmacologyDOI:10.1016/j.coph.2018.10.001