Current Opinion in Chemical Biology is a systematic review journal that aims to provide specialists with a unique and educational platform to keep up to date with the expanding volume of information published in the field of Chemical Biology. The journal publishes 6 issues per year covering the following 10 sections, each of which is reviewed once a year, these are: Omics, Biocatalysis and Biotransformation, Bioinorganic Chemistry, Next Generation Therapeutics, Molecular Imaging, Chemical Genetics and Epigenetics, Synthetic Biology, Synthetic Biomolecules and Mechanistic Biology. There is also a section that changes regularly to reflect hot topics in the field.
Current Opinion in Chemical Biology是一本系统性综述期刊,旨在为专家提供一个独特的教育平台,以跟上化学生物学领域不断增长的信息量。该杂志每年出版6期,涵盖以下10个部分,每个部分每年审查一次,这些部分是:组学、生物催化和生物转化、生物无机化学、下一代治疗学、分子成像、化学遗传学和表观遗传学、合成生物学、合成生物分子和机械生物学。还有一个部分会定期变化,以反映该领域的热点话题。
Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.10.004
Advances and opportunities for the design of self-sufficient and spatially organized cell-free biocatalytic systems.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.11.021
Protein identification strategies in MALDI imaging mass spectrometry: a brief review.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.10.023
Bifunctional chemical probes inducing protein-protein interactions.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.07.003
Role of rare earth elements in methanol oxidation.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.019
Recent preparative applications of redox enzymes.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.11.011
Whole-cell based synthetic enzyme cascades-light and shadow of a promising technology.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.10.016
Reactive sulfur species (RSS): persulfides, polysulfides, potential, and problems.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.08.012
Towards functional de novo designed proteins.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.06.011
Reactive-cysteine profiling for drug discovery.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.02.010
An overview of activity-based probes for glycosidases.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.05.030
Enzymatic CH functionalizations for natural product synthesis.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.004
New discoveries in bacterial N-glycosylation to expand the synthetic biology toolbox.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.05.032
Nucleic acid enzymes based on functionalized nucleosides.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.06.007
Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)-processing enzymes.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.09.001
Updates on the epigenetic roles of sirtuins.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.01.023
Modulating protein-protein interaction networks in protein homeostasis.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.02.012
Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.03.002
The subcellular organisation of Saccharomyces cerevisiae
来源期刊:Current Opinion in Chemical BiologyDOI:10.1016/j.cbpa.2018.10.026
Recent progress in the development of organometallics for the treatment of cancer.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.11.001
Assessing sub-cellular resolution in spatial proteomics experiments
来源期刊:Current Opinion in Chemical BiologyDOI:10.1016/j.cbpa.2018.11.015
Activity-based protein profiling in bacteria: Applications for identification of therapeutic targets and characterization of microbial communities.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.10.007
Recent achievements and current trajectories of diversity-oriented synthesis.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.08.008
The antimalarial screening landscape—looking beyond the asexual blood stage
来源期刊:Current Opinion in Chemical BiologyDOI:10.1016/j.cbpa.2019.01.029
Machine learning for target discovery in drug development.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.10.003
How to make the reducing power of H2 available for in vivo biosyntheses and biotransformations.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.11.020
Label-free target identification in drug discovery via phenotypic screening.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.02.006
A role for phosphorus redox in emerging and modern biochemistry.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.018
Metal regulation of metabolism.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.017
Lectin antagonists in infection, immunity, and inflammation.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.07.005
Proteomics of nucleocytoplasmic partitioning.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.10.027
Bacterial carbohydrate diversity - a Brave New World.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.04.026
Fungal PQQ-dependent dehydrogenases and their potential in biocatalysis.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.12.001
Dynamics of protein complex components.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.11.003
Strategies for increasing the throughput of super-resolution microscopies.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.05.012
DNA barcodes evolve for high-resolution cell lineage tracing.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.05.014
Natural products as chemical tools to dissect complex biology in C. elegans.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.03.005
Pharmacokinetic-pharmacodynamic models that incorporate drug-target binding kinetics.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.03.008
Using chemical inhibitors to probe AAA protein conformational dynamics and cellular functions.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.02.019
Biocatalytic hydrogen atom transfer: an invigorating approach to free-radical reactions.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.001
High-throughput approaches to profile RNA-protein interactions.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.11.002
Understanding molecular mechanisms of disease through spatial proteomics.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2018.09.016
Functional super-resolution microscopy of the cell.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.05.016
CRISPR/Cas-based devices for mammalian synthetic biology.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.04.015
Construction of ligand assay systems by protein-based semisynthetic biosensors.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.02.011
Mammalian gene circuits with biomolecule-responsive RNA devices.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.04.013
Chemically induced cell fate reprogramming and the acquisition of plasticity in somatic cells.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.04.025
Chemoproteomic profiling of protein-metabolite interactions.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.11.003
Emerging technologies in mechanotransduction research.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.08.002
Modeling catalytic reaction mechanisms in glycoside hydrolases.
来源期刊:Current opinion in chemical biologyDOI:10.1016/j.cbpa.2019.09.007