Current Gene Therapy is a bi-monthly peer-reviewed journal aimed at academic and industrial scientists with an interest in major topics concerning basic research and clinical applications of gene and cell therapy of diseases. Cell therapy manuscripts can also include application in diseases when cells have been genetically modified. Current Gene Therapy publishes full-length/mini reviews and original research on the latest developments in gene transfer and gene expression analysis, vector development, cellular genetic engineering, animal models and human clinical applications of gene and cell therapy for the treatment of diseases.Current Gene Therapy publishes reviews and original research containing experimental data on gene and cell therapy. The journal also includes manuscripts on technological advances, ethical and regulatory considerations of gene and cell therapy. Reviews should provide the reader with a comprehensive assessment of any area of experimental biology applied to molecular medicine that is not only of significance within a particular field of gene therapy and cell therapy but also of interest to investigators in other fields. Authors are encouraged to provide their own assessment and vision for future advances. Reviews are also welcome on late breaking discoveries on which substantial literature has not yet been amassed. Such reviews provide a forum for sharply focused topics of recent experimental investigations in gene therapy primarily to make these results accessible to both clinical and basic researchers. Manuscripts containing experimental data should be original data, not previously published.
《当代基因治疗》是一份双月刊同行评审期刊,面向对基因和细胞治疗疾病的基础研究和临床应用相关重大主题感兴趣的学术和工业科学家。细胞治疗手稿也可以包括在疾病中的应用,当细胞已经遗传修饰。《当代基因治疗》发表有关基因转移和基因表达分析、载体开发、细胞遗传工程、动物模型和基因与细胞治疗疾病的人类临床应用的最新发展的全文/小型综述和原创研究。《当代基因治疗》发表包含基因与细胞治疗实验数据的综述和原创研究。该杂志还包括有关基因和细胞治疗的技术进步、伦理和监管考虑的手稿。综述应向读者提供应用于分子医学的任何实验生物学领域的全面评估,这些领域不仅在基因治疗和细胞治疗的特定领域具有重要意义,而且对其他领域的研究者也有意义。鼓励作者提供自己的评估和未来发展的愿景。对于尚未积累大量文献的最新发现,也欢迎进行审查。这些综述为最近基因治疗实验研究的尖锐焦点主题提供了一个论坛,主要是为了使临床和基础研究人员都能获得这些结果。包含实验数据的手稿应是原始数据,之前未发表过。
Computational and Biological Methods for Gene Therapy.
来源期刊:Current gene therapyDOI:10.2174/156652321904191022113307
Current RNA-based Therapeutics in Clinical Trials.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190719100526
The Therapeutic Potential and Role of miRNA, lncRNA, and circRNA in Osteoarthritis.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190716092203
Functional Improvement of Chimeric Antigen Receptor Through Intrinsic Interleukin-15Rα Signaling.
来源期刊:Current gene therapyDOI:10.2174/1566523218666181116093857
A Mendelian Randomization Study of Infant Length and Type 2 Diabetes Mellitus Risk.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190925115535
Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190621113807
The Relationship between Ferroptosis and Tumors: A Novel Landscape for Therapeutic Approach
来源期刊:Current Gene TherapyDOI:10.2174/1566523219666190628152137
Non-coding RNA associated Competitive Endogenous RNA Regulatory Network: Novel Therapeutic Approach in Liver Fibrosis.
来源期刊:Current gene therapyDOI:10.2174/1566523219666191107113046
High Mobility Group Box 1: An Immune-regulatory Protein.
来源期刊:Current Gene TherapyDOI:10.2174/1566523219666190621111604
Cell Therapy in Solid Organ Transplantation.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190603103840
Understanding Gene Therapy in Acute Respiratory Distress Syndrome.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190702154817
Comparative Activity of Adenosine Deaminase Acting on RNA (ADARs) Isoforms for Correction of Genetic Code in Gene Therapy.
来源期刊:Current gene therapyDOI:10.2174/1566523218666181114122116
Functional Immunoregulation by Heme Oxygenase 1 in Juvenile Autoimmune Diseases.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190710092935
Prediction of Disease Comorbidity Using HeteSim Scores based on Multiple Heterogeneous Networks.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190917155959
Correlation between MDSC and Immune Tolerance in Transplantation: Cytokines, Pathways and Cell-cell Interaction.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190618093707
Effect of Tumor Suppressor MiR-34a Loaded on ZSM-5 Nanozeolite in Hepatocellular Carcinoma: In Vitro and In Vivo Approach.
来源期刊:Current gene therapyDOI:10.2174/1566523219666191108103739
Nanomedicine for Gene Delivery for the Treatment of Cardiovascular Diseases
来源期刊:Current Gene TherapyDOI:10.2174/1566523218666181003125308
The promise of miRNA replacement therapy for Hepatocellular carcinoma.
来源期刊:Current gene therapyDOI:10.2174/1566523219666191023101433
A Recurrent Rare SOX9 Variant (M469V) is Associated with Congenital Vertebral Malformations.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190924120307
Novel Combination Oncolytic Adenoviral Gene Therapy Armed with Dm-dNK and CD40L for Breast Cancer.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190307094713
Three Cases of Leber’s Hereditary Optic Neuropathy with Rapid Increase in Visual Acuity After Gene Therapy
来源期刊:Current Gene TherapyDOI:10.2174/1566523219666190618094505
Suicide Gene Therapy Against Malignant Gliomas by the Local Delivery of Genetically Engineered Umbilical Cord Mesenchymal Stem Cells as Cellular Vehicles.
来源期刊:Current gene therapyDOI:10.2174/1566523219666191028103703
Effects of Huangkui Capsule on the Expression of SPARC in the Kidney Tissue of a Rat Model with Diabetic Nephropathy.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190925112249
Hemophilia Gene Therapy: From Bench to Bed Side.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190924121836
Nano-enhanced optical gene delivery to retinal degenerated mice.
来源期刊:Current gene therapyDOI:10.2174/1566523219666191017114044
The Synergy between CRISPR and Chemical Engineering.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190701100556
Gene-based Therapeutic Tools in the Treatment of Cornea Disease.
来源期刊:Current gene therapyDOI:10.2174/1566523219666181213120634
Biodegradable Polyester of Poly (Ethylene glycol)-sebacic Acid as a Backbone for β-Cyclodextrin-polyrotaxane: A Promising Gene Silencing Vector.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190808094225
The therapeutic potential of small activating RNAs for colorectal carcinoma.
来源期刊:Current gene therapyDOI:10.2174/1566523219666190708111404