Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism, pharmacokinetics, and drug disposition. The journal serves as an international forum for the publication of full-length/mini review, research articles and guest edited issues in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the most important developments. The journal covers the following general topic areas: pharmaceutics, pharmacokinetics, toxicology, and most importantly drug metabolism.More specifically, in vitro and in vivo drug metabolism of phase I and phase II enzymes or metabolic pathways; drug-drug interactions and enzyme kinetics; pharmacokinetics, pharmacokinetic-pharmacodynamic modeling, and toxicokinetics; interspecies differences in metabolism or pharmacokinetics, species scaling and extrapolations; drug transporters; target organ toxicity and interindividual variability in drug exposure-response; extrahepatic metabolism; bioactivation, reactive metabolites, and developments for the identification of drug metabolites. Preclinical and clinical reviews describing the drug metabolism and pharmacokinetics of marketed drugs or drug classes.
当前药物代谢旨在涵盖药物代谢、药代动力学和药物处置方面的所有最新和突出进展。该杂志是发表药物代谢方面的长篇/小型综述、研究文章和客座编辑问题的国际论坛。《现代药物代谢》是学术、临床、政府和制药科学家的重要期刊，他们希望了解最重要的进展。该杂志涵盖以下一般主题领域：药学、药代动力学、毒理学和最重要的药物代谢。更具体地，I期和II期酶或代谢途径的体外和体内药物代谢;药物相互作用和酶动力学;药代动力学、药代动力学-药效学建模和毒代动力学;代谢或药代动力学的种间差异、种属缩放和外推;药物转运蛋白;靶器官毒性和药物暴露-反应的个体间变异性;肝外代谢;生物活化、反应性代谢物和药物代谢物鉴定的发展。描述上市药物或药物类别的药物代谢和药代动力学的临床前和临床综述。
The Impact of Carboxylesterases in Drug Metabolism and Pharmacokinetics
来源期刊：Current Drug MetabolismDOI：10.2174/1389200219666180821094502
Targeting Virus-host Protein Interactions: Feature Extraction and Machine Learning Approaches.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180829121038
Herb-Drug Interactions and Hepatotoxicity.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190325141422
Recent Advances in the Machine Learning-Based Drug-Target Interaction Prediction.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180821094047
Drug-Drug Interactions of P-gp Substrates Unrelated to CYP Metabolism.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666181003142036
Cross-regulatory Circuit Between AHR and Microbiota.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180129151150
Application of Traditional Chinese Herbal Medicine By-products as Dietary Feed Supplements and Antibiotic Replacements in Animal Production.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180523102920
A Review of Recent Advances and Research on Drug Target Identification Methods.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180925091851
Advanced Glycation End Products (AGEs), Glutathione and Breast Cancer: Factors, Mechanism and Therapeutic Interventions.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180912104342
The Therapeutic Role of Xenobiotic Nuclear Receptors Against Metabolic Syndrome.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180611083155
PI3K/Akt-Nrf2 and Anti-Inflammation Effect of Macrolides in Chronic Obstructive Pulmonary Disease.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190227224748
The Relationship Between the Serotonin Metabolism, Gut-Microbiota and the Gut-Brain Axis.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190725115503
Preclinical Pharmacokinetics of Triptolide: A Potential Antitumor Drug.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180816141506
Genitourinary Tumors: Update on Molecular Biomarkers for Diagnosis, Prognosis and Prediction of Response to Therapy.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190225124352
Impact of Drug Metabolism/Pharmacokinetics and their Relevance Upon Traditional Medicine-based Cardiovascular Drug Research.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190618101526
Curcumin - A Novel Therapeutic Agent In The Prevention Of Colorectal Cancer.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191007153238
Nanomedicine: Bioavailability, Biotransformation and Biokinetics.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190614150708
Kisspeptin and its Effect on Mammalian Spermatogensis.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666180129112406
A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190709170256
Effects of Gut Microbiota on Drug Metabolism and Guidance for Rational Drug Use Under Hypoxic Conditions at High Altitudes.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666181019145159
Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model
来源期刊：Current Drug MetabolismDOI：10.2174/1389200219666181003143312
Neuroblastoma: An updated review on biology and treatment.
来源期刊：Current drug metabolismDOI：10.2174/1389200221666191226102231
Clinical Implications of Methotrexate Pharmacogenetics in Childhood Acute Lymphoblastic Leukaemia.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190130161758
A systematic investigation of the effects of long-term administration of a high-fat diet on drug transporters in the mouse liver, kidney and intestine.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190902125435
The Role of the Sodium-taurocholate Co-transporting Polypeptide (NTCP) and Bile Salt Export Pump (BSEP) in Related Liver Disease.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190426152830
Decreased Disposition of Anticancer Drugs Predominantly Eliminated via the Liver in Patients with Renal Failure
来源期刊：Current Drug MetabolismDOI：10.2174/1389200220666190402143125
Influence of the OATP Polymorphism on the Population Pharmacokinetics of Methotrexate in Chinese Patients
来源期刊：Current Drug MetabolismDOI：10.2174/1389200220666190701094756
Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for Diagnosis and Treatment of Breast, Ovarian and Cervical Cancers.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191016124958
Evaluation Of Pharmacokinetic Interaction of Cilostazol with Metoclopramide after Oral Administration in Human.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191105115805
Assessment of miR-212 and Other Biomarkers in the Diagnosis and Treatment of HBV-infection-related Liver Diseases.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191011120434
The Development of Machine Learning Methods in Cell-Penetrating Peptides Identification: A Brief Review.
来源期刊：Current drug metabolismDOI：10.2174/1389200219666181010114750
Emerging Trends in Nanotechnology: Nanozymes, Imaging Probes and Biosensors and Nanocarriers.
来源期刊：Current drug metabolismDOI：10.2174/138920022006190617104713
Interethnic variations of UGT1A1 and UGT1A7 Polymorphisms in the Jordanian Population.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190528085151
Recognition Sites for Cancer-Targeting Durg Delivery Systems.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191003161114
Effects of CYP2C8 and SLCO1B1 Genetic Polymorphisms on Repaglinide Pharmacokinetics: A Systematic Review and Meta-Analysis.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190111114146
Recent Advances on Prediction of Human Papillomaviruses Risk Types.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190118110012
Associations of CYP2A6 Gene Polymorphism with Smoking Status among Jordanians: Gender-Related Differences.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190827161112
Interaction Between Traditional Chinese Medicine and Anticoagulant/antiplatelet Drugs.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190827160212
Curcumin-C3 Complexed With α-, β-cyclodextrin Exhibits Antibacterial and Antioxidant Properties Suitable for Cancer Treatments.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191001104834
Recent Findings on Nanotechnology-based Therapeutic Strategies Against Hepatocellular Carcinoma.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190308134351
Role of Cellular Biomolecules in Screening, Diagnosis, and Treatment of Colorectal Cancer.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191018153428
A Retrospective Look at Anti-EGFR Agents in Pancreatic Cancer Therapy.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191122104955
Oral Delivery of Anticancer Agents using Nanoparticulate Drug Delivery System.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191007154017
Naphthalene Toxicity in Clinical Practice.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191122110036
Warfarin Dosing and Outcomes in Chronic Kidney Disease: A Closer Look at Warfarin Disposition.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190701095807
Delivery of Local Anesthesia: Current Strategies, Safety, and Future Prospects.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190610155049
Higher Atazanavir plasma exposure in Rats is associated with Gut Microbiota Changes induced by Cotrimoxazole.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191023105609
Hepatic Artery and Peripheral Vein Pharmacokinetics of Raltitrexed in Swine After the Administration of a Hepatic Arterial Infusion.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666190618100847
Challenges in the Discovery of Novel Therapeutic Agents in Cancer.
来源期刊：Current drug metabolismDOI：10.2174/138920022012200102095006
Monocarboxylate transporter 1: A promising drug-delivery target in the treatment of brain diseases and cancers.
来源期刊：Current drug metabolismDOI：10.2174/1389200220666191021103018
