GeroScience is a bi-monthly, international, peer-reviewed journal that publishes articles related to research in the biology of aging and research on biomedical applications that impact aging. The scope of articles to be considered include evolutionary biology, biophysics, genetics, genomics, proteomics, molecular biology, cell biology, biochemistry, endocrinology, immunology, physiology, pharmacology, neuroscience, and psychology.
GeroScience是一个双月刊、国际同行评审期刊，发表与衰老生物学研究和影响衰老的生物医学应用研究相关的文章。考虑的文章范围包括进化生物学、生物物理学、遗传学、基因组学、蛋白质组学、分子生物学、细胞生物学、生物化学、内分泌学、免疫学、生理学、药理学、神经科学和心理学。
Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00101-2
Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases
来源期刊：GeroScienceDOI：10.1007/s11357-019-00107-w
Topical rapamycin reduces markers of senescence and aging in human skin: an exploratory, prospective, randomized trial
来源期刊：GeroScienceDOI：10.1007/s11357-019-00113-y
The potential role of necroptosis in inflammaging and aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00131-w
Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00065-3
An expanding GSK3 network: implications for aging research
来源期刊：GeroScienceDOI：10.1007/s11357-019-00085-z
Sulfoaphane - role in aging and neurodegeneration
来源期刊：GeroScienceDOI：10.1007/s11357-019-00061-7
Lipotoxicity, aging, and muscle contractility: does fiber type matter?
来源期刊：GeroScienceDOI：10.1007/s11357-019-00077-z
Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00111-0
Effect of caloric restriction and rapamycin on ovarian aging in mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00087-x
Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14ARF, and TAU3 transcript expression and contribute to cognitive decline
来源期刊：GeroScienceDOI：10.1007/s11357-019-00100-3
Gastro-intestinal and oral microbiome signatures associated with healthy aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00098-8
Taming expectations of metformin as a treatment to extend healthspan
来源期刊：GeroScienceDOI：10.1007/s11357-019-00057-3
The influence of GDF11 on brain fate and function
来源期刊：GeroScienceDOI：10.1007/s11357-019-00054-6
Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans
来源期刊：GeroScienceDOI：10.1007/s11357-019-00122-x
The effect of fear of falling on prefrontal cortex activation and efficiency during walking in older adults
来源期刊：GeroScienceDOI：10.1007/s11357-019-00056-4
Genomic instability and innate immune responses to self-DNA in progeria
来源期刊：GeroScienceDOI：10.1007/s11357-019-00082-2
Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00102-1
Systolic hypertension-induced neurovascular unit disruption magnifies vascular cognitive impairment in middle-age atherosclerotic LDLr−/−:hApoB+/+ mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00070-6
Accelerated decline in cognition in a mouse model of increased oxidative stress
来源期刊：GeroScienceDOI：10.1007/s11357-019-00105-y
Astrocyte senescence contributes to cognitive decline
来源期刊：GeroScienceDOI：10.1007/s11357-019-00140-9
Genetic heterogeneity of Alzheimer’s disease in subjects with and without hypertension
来源期刊：GeroScienceDOI：10.1007/s11357-019-00071-5
Cellular energetics and mitochondrial uncoupling in canine aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00062-6
circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan
来源期刊：GeroScienceDOI：10.1007/s11357-019-00120-z
Age-dependent effects of caloric restriction on mTOR and ubiquitin-proteasome pathways in skeletal muscles
来源期刊：GeroScienceDOI：10.1007/s11357-019-00109-8
The effects of cardiorespiratory fitness on executive function and prefrontal oxygenation in older adults
来源期刊：GeroScienceDOI：10.1007/s11357-019-00128-5
WormBot, an open-source robotics platform for survival and behavior analysis in C. elegans
来源期刊：GeroScienceDOI：10.1007/s11357-019-00124-9
The role of exercise in the reversal of IGF-1 deficiencies in microvascular rarefaction and hypertension
来源期刊：GeroScienceDOI：10.1007/s11357-019-00139-2
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer’s disease
来源期刊：GeroScienceDOI：10.1007/s11357-019-00127-6
Raman fingerprints as promising markers of cellular senescence and aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00053-7
Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies
来源期刊：GeroScienceDOI：10.1007/s11357-019-00090-2
Tryptophan metabolism is differently regulated between large and small dogs
来源期刊：GeroScienceDOI：10.1007/s11357-019-00114-x
Dysregulation of the SNARE-binding protein Munc18-1 impairs BDNF secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain
来源期刊：GeroScienceDOI：10.1007/s11357-019-00067-1
Differential effects of various genetic mouse models of the mechanistic target of rapamycin complex I inhibition on heart failure
来源期刊：GeroScienceDOI：10.1007/s11357-019-00119-6
Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions
来源期刊：GeroScienceDOI：10.1007/s11357-019-00108-9
The association of anxio-depressive disorders and depression with motoric cognitive risk syndrome: results from the baseline assessment of the Canadian longitudinal study on aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00093-z
Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations
来源期刊：GeroScienceDOI：10.1007/s11357-019-00112-z
Novel individualized power training protocol preserves physical function in adult and older mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00069-z
Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells
来源期刊：GeroScienceDOI：10.1007/s11357-019-00099-7
Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases
来源期刊：GeroScienceDOI：10.1007/s11357-019-00106-x
Individual evaluation of luteinizing hormone in aged C57BL/6 J female mice
来源期刊：GeroScienceDOI：10.1007/s11357-019-00104-z
Lumbar spinal cord microglia exhibited increased activation in aging dogs compared with young adult dogs
来源期刊：GeroScienceDOI：10.1007/s11357-019-00133-8
Proceedings from the Albert Charitable Trust Inaugural Workshop on white matter and cognition in aging
来源期刊：GeroScienceDOI：10.1007/s11357-019-00141-8
Anti-inflammatory agent, OKN-007, reverses long-term neuroinflammatory responses in a rat encephalopathy model as assessed by multi-parametric MRI: implications for aging-associated neuroinflammation
来源期刊：GeroScienceDOI：10.1007/s11357-019-00094-y
Aging induced by D-galactose aggravates cardiac dysfunction via exacerbating mitochondrial dysfunction in obese insulin-resistant rats
来源期刊：GeroScienceDOI：10.1007/s11357-019-00132-9
Genetic conversion of proliferative astroglia into neurons after cerebral ischemia: a new therapeutic tool for the aged brain?
来源期刊：GeroScienceDOI：10.1007/s11357-019-00084-0
High rates of undiagnosed vascular cognitive impairment among American Indian veterans
来源期刊：GeroScienceDOI：10.1007/s11357-019-00055-5
The transfer of specific mitochondrial lipids and proteins to lipid droplets contributes to proteostasis upon stress and aging in the eukaryotic model system Saccharomyces cerevisiae
来源期刊：GeroScienceDOI：10.1007/s11357-019-00103-0
Correction to: Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells
来源期刊：GeroScienceDOI：10.1007/s11357-019-00144-5
Polygenic risk score for disability and insights into disability-related molecular mechanisms
来源期刊：GeroScienceDOI：10.1007/s11357-019-00125-8
