ALTEX publishes original articles, short communications, reviews, as well as news and comments and meeting reports. Manuscripts submitted to ALTEX are evaluated by two expert reviewers. The evaluation takes into account the scientific merit of a manuscript and its contribution to animal welfare and the 3R principle.
ALTEX出版原创文章、简短通信、评论以及新闻、评论和会议报告。提交给ALTEX的手稿由两名专家评审员进行评估。评价考虑了手稿的科学价值及其对动物福利和3R原则的贡献。
A modular approach for assembly of quantitative adverse outcome pathways.
来源期刊：ALTEXDOI：10.14573/altex.1810181
A novel approach to increase robustness, precision and high-throughput capacity of single cell gel electrophoresis.
来源期刊：ALTEXDOI：10.14573/altex.1906252
A rational approach of early humane endpoint determination in a murine model for cholestasis.
来源期刊：ALTEXDOI：10.14573/altex.1909111
A three-dimensional model to study human synovial pathology.
来源期刊：ALTEXDOI：10.14573/altex.1804161
Activation of TRPA1 by volatile organic chemicals leading to sensory irritation.
来源期刊：ALTEXDOI：10.14573/altex.1811012
Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research.
来源期刊：ALTEXDOI：10.14573/altex.1907031
Toward Good In Vitro Reporting Standards.
来源期刊：ALTEXDOI：10.14573/altex.1812191
Chemical hazard prediction and hypothesis testing using quantitative adverse outcome pathways.
来源期刊：ALTEXDOI：10.14573/altex.1808241
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
来源期刊：ALTEXDOI：10.14573/altex.1909271
Generalized Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard.
来源期刊：ALTEXDOI：10.14573/altex.1811292
Botulinum toxin testing on animals is still a Europe-wide issue.
来源期刊：ALTEXDOI：10.14573/altex.1807101
Characterizing sources of variability in zebrafish embryo screening protocols.
来源期刊：ALTEXDOI：10.14573/altex.1804162
Developing context appropriate toxicity testing approaches using new alternative methods (NAMs).
来源期刊：ALTEXDOI：10.14573/altex.1906261
The impact of precision uncertainty on predictive accuracy metrics of non-animal testing methods.
来源期刊：ALTEXDOI：10.14573/altex.1810111
Investigating cell type specific mechanisms contributing to acute oral toxicity.
来源期刊：ALTEXDOI：10.14573/altex.1805181
An in vitro coculture system for the detection of sensitization following aerosol exposure.
来源期刊：ALTEXDOI：10.14573/altex.1901241
Rheumatoid arthritis research in the 21st century: Limitations of traditional models, new technologies, and opportunities for a human biology-based approach.
来源期刊：ALTEXDOI：10.14573/altex.1910011
The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity.
来源期刊：ALTEXDOI：10.14573/altex.1905031
Software tools for literature screening in systematic reviews in biomedical research.
来源期刊：ALTEXDOI：10.14573/altex.1902131
Chemical concentrations in cell culture compartments (C5) - concentration definitions.
来源期刊：ALTEXDOI：10.14573/altex.1901031
Assessment of iron oxide nanoparticle ecotoxicity on regeneration and homeostasis in the replacement model system Schmidtea mediterranea.
来源期刊：ALTEXDOI：10.14573/altex.1902061
Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing.
来源期刊：ALTEXDOI：10.14573/altex.1812051
Machine learning prediction of cyanobacterial toxin (microcystin) toxicodynamics in humans.
来源期刊：ALTEXDOI：10.14573/altex.1904031
Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays.
来源期刊：ALTEXDOI：10.14573/altex.1912021
Refining humane endpoints in mouse models of disease by systematic review and machine learning-based endpoint definition.
来源期刊：ALTEXDOI：10.14573/altex.1812231
Insights into in vitro biokinetics using Virtual Cell Based Assay simulations.
来源期刊：ALTEXDOI：10.14573/altex.1812101
Recent advances in 3Rs and laboratory animal science: Report on the International Conference of LASA (India).
来源期刊：ALTEXDOI：10.14573/altex.1901041
Improved defined approaches for predicting skin sensitization hazard and potency in humans.
来源期刊：ALTEXDOI：10.14573/altex.1809191
The current status of alternative methods for cosmetics safety assessment in China.
来源期刊：ALTEXDOI：10.14573/altex.1808021
Comparison of in chemico skin sensitization methods and development of an in chemico skin photosensitization assay.
来源期刊：ALTEXDOI：10.14573/altex.1811011
Innovative in vitro method to study ventilator induced lung injury.
来源期刊：ALTEXDOI：10.14573/altex.1901182
Opportunities for refinement in neuroscience: Indicators of wellness and post-operative pain in laboratory macaques.
来源期刊：ALTEXDOI：10.14573/altex.1811061
Presence of vasculature results in faster insulin response in adipocytes in vascularized adipose tissue model.
来源期刊：ALTEXDOI：10.14573/altex.1811271
Extending the concept of predicting fish acute toxicity in vitro to the intestinal cell line RTgutGC.
来源期刊：ALTEXDOI：10.14573/altex.1905032
Advice on avoiding the Valley of Death: insights from a 3Rs model of aversive and emetic compound identification.
来源期刊：ALTEXDOI：10.14573/altex.1810182
Integrating adverse outcome pathways (AOPs) and high throughput in vitro assays for better risk evaluations, a study with drug-induced liver injury (DILI).
来源期刊：ALTEXDOI：10.14573/altex.1908151
Addressing potential ethical issues regarding the supply of human-derived products or reagents in in vitro OECD Test Guidelines.
来源期刊：ALTEXDOI：10.14573/altex.1901281
SUIKER: Quantification of antigens in cell organelles, neurites and cellular sub-structures by imaging.
来源期刊：ALTEXDOI：10.14573/altex.1906251
Zebrafish embryo and acute fish toxicity test show similar sensitivity for narcotic compounds.
来源期刊：ALTEXDOI：10.14573/altex.1808101
Corrigendum to Normalization of data for viability and relative cell function curves.
来源期刊：ALTEXDOI：10.14573/altex.1904113
Applications for animal experiments are rarely rejected in Germany.
来源期刊：ALTEXDOI：10.14573/altex.1906111
Bisphenol A binding promiscuity: A virtual journey through the universe of proteins.
来源期刊：ALTEXDOI：10.14573/altex.1906141
Corrigendum to A high-throughput approach to identify specific neurotoxicants / developmental toxicants in human neuronal cell function assays.
来源期刊：ALTEXDOI：10.14573/altex.1904111
Corrigendum to Chemical concentrations in cell culture compartments (C⁵) - concentration definitions.
来源期刊：ALTEXDOI：10.14573/altex.1904115
Use of alternative methods: From fundamental to industrial research.
来源期刊：ALTEXDOI：10.14573/altex.1812172
Science and alternative methods: Integrated approaches.
来源期刊：ALTEXDOI：10.14573/altex.1901301
Development of an ex vivo aneurysm model for vascular devices testing.
来源期刊：ALTEXDOI：10.14573/altex.1906253
Corrigendum to Essential components of methods papers.
来源期刊：ALTEXDOI：10.14573/altex.1904114
The value of organs-on-chip for regulatory safety assessment.
来源期刊：ALTEXDOI：10.14573/altex.1910111
