Drugs in R&D is an international, peer reviewed, open access, online only journal, and provides timely information from all phases of drug research and development that will inform clinical practice. Healthcare decision makers are thus provided with knowledge about the developing place of a drug in therapy. The Journal includes: Clinical research on new and established drugs; Preclinical research of direct relevance to clinical drug development; Short communications and case study reports that meet the above criteria will also be considered; Reviews may also be considered.
研发中的药物Drugs in R&D是一本国际性、同行评审、开放获取、仅在线的期刊，提供来自药物研发各个阶段的及时信息，为临床实践提供信息。医疗保健决策者因此提供了有关药物在治疗中的发展位置的知识。与临床药物开发直接相关的临床前研究;符合上述标准的简短通信和案例研究报告也将得到考虑;也可考虑进行审查。
Bortezomib for the Treatment of Hematologic Malignancies: 15 Years Later
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0269-9
Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0266-z
A Clinician’s Guide to the Recognition and Management of Dupilumab-Associated Conjunctivitis
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00288-x
Monitoring the Efficacy and Safety of Artemisinin-Based Combination Therapies: A Review and Network Meta-analysis of Antimalarial Therapeutic Efficacy Trials in Cameroon
来源期刊：Drugs in R&DDOI：10.1007/s40268-018-0259-3
Neuropsychiatric Symptoms in Dementia: Considerations for Pharmacotherapy in the USA
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0272-1
The Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00286-z
Elderly Bleeding Risk of Direct Oral Anticoagulants in Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis of Cohort Studies
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0275-y
Ulcerative Colitis: Shifting Sands
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0263-2
S-1 in Patients with Advanced Esophagogastric Adenocarcinoma: Results from the Safety Compliance Observatory on Oral fluoroPyrimidines (SCOOP) Study
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0265-0
Are Standard Doses of Renally-Excreted Antiretrovirals in Older Patients Appropriate: A PBPK Study Comparing Exposures in the Elderly Population With Those in Renal Impairment
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00285-0
Comparison of the New Oral Anticoagulants and Warfarin in Patients with Atrial Fibrillation and Valvular Heart Disease: Systematic Review and Meta-Analysis
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0274-z
The Effect of Fluctuating Temperature on the Stability of Turoctocog Alfa for Hemophilia A
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00290-3
Extrapolation of Drug Clearance in Children ≤\u20092 Years of Age from Empirical Models Using Data from Children (>\u20092 Years) and Adults
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00291-2
Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00284-1
Characterization of the Pharmacokinetics of Samidorphan in Healthy Volunteers: Absolute Bioavailability and the Effect of Food and Age
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00280-5
Inhaled Loxapine for the Management of Acute Agitation in Bipolar Disorder and Schizophrenia: Expert Review and Commentary in an Era of Change
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0262-3
Amount of Cycloserine Emanating from Terizidone Metabolism and Relationship with Hepatic Function in Patients with Drug-Resistant Tuberculosis
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00281-4
Timing of GLP-1 Receptor Agonist Initiation for Treatment of Type 2 Diabetes in the UK
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0273-0
A Novel, Dose-Adjusted Tacrolimus Trough-Concentration Model for Predicting and Estimating Variance After Kidney Transplantation
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0271-2
Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients?
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0261-4
Towards a Generic Tool for Prediction of Meropenem Systemic and Infection-Site Exposure: A Physiologically Based Pharmacokinetic Model for Adult Patients with Pneumonia
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0268-x
Pharmacokinetics of Sublingual Buprenorphine Tablets Following Single and Multiple Doses in Chinese Participants With and Without Opioid Use Disorder
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0277-9
Use of Selective Serotonin Reuptake Inhibitors and Outcomes in Stroke Rehabilitation: A Prospective Observational Pilot Cohort Study
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00287-y
Prediction of Drug–Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00282-3
Assessing the Extended In-Use Stability of the Infliximab Biosimilar PF-06438179/GP1111 Following Preparation for Intravenous Infusion
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0264-1
Assessment of Taste and Grittiness of Riomet® ER Strawberry, Riomet® ER Grape, Riomet® Cherry, and Metformin Immediate-Release Tablets in Healthy Subjects
来源期刊：Drugs in R&DDOI：10.1007/s40268-018-0260-x
Post-Marketing Surveillance of Silodosin in Patients with Benign Prostatic Hyperplasia and Poor Response to Existing Alpha-1 Blockers: The SPLASH Study
来源期刊：Drugs in R&DDOI：10.1007/s40268-018-0258-4
Vasodepressor Effects of Adenosine in the Cat are Independent of Cyclooxygenase, Potassium Channels, and Nitric Oxide Pathways
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00283-2
Correction to: Safety and Efficacy of 0.5% Carbomer 980 Gel for Treatment of Symptoms of Common Cold: Results of 2 Randomized Trials
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0279-7
Acknowledgement to Referees
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-00289-w
Safety and Efficacy of 0.5% Carbomer 980 Gel for Treatment of Symptoms of Common Cold: Results of 2 Randomized Trials
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0270-3
Impact of Primary Tumour Location and Early Tumour Shrinkage on Outcomes in Patients with RAS Wild-Type Metastatic Colorectal Cancer Following First-Line FOLFIRI Plus Panitumumab
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0278-8
Effects of Food on the Bioavailability of Amphetamine in Healthy Adults After Administration of SHP465 Mixed Amphetamine Salts Extended-Release Capsules
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0267-y
Effects of Age Among Elderly Cancer Patients on Breakthrough Pain Management with Sublingual Fentanyl Tablets
来源期刊：Drugs in R&DDOI：10.1007/s40268-019-0276-x
