Pharmacogenetics and Genomics is devoted to the rapid publication of research papers, brief review articles and short communications on genetic determinants in response to drugs and other chemicals in humans and animals. The Journal brings together papers from the entire spectrum of biomedical research and science, including biochemistry, bioinformatics, clinical pharmacology, clinical pharmacy, epidemiology, genetics, genomics, molecular biology, pharmacology, pharmaceutical sciences, and toxicology. Under a single cover, the Journal provides a forum for all aspects of the genetics and genomics of host response to exogenous chemicals: from the gene to the clinic.
药物遗传学和基因组学致力于快速发表关于人类和动物对药物和其他化学品反应的遗传决定因素的研究论文、简要综述文章和简短通信。该期刊汇集了来自生物医学研究和科学的整个领域的论文,包括生物化学、生物信息学、临床药理学、临床药学、流行病学、遗传学、基因组学、分子生物学、药理学、药学科学和毒理学。在一个单一的封面下,该杂志提供了一个论坛,讨论宿主对外源化学物质反应的遗传学和基因组学的各个方面:从基因到临床。
Assessing the clinical impact of CYP2C9 pharmacogenetic variation on phenytoin prescribing practice and patient response in an integrated health system.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000383
CYP2D6 haplotypes with enhancer single-nucleotide polymorphism rs5758550 and rs16947 (*2 allele): implications for CYP2D6 genotyping panels
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000363
Assessment of provider-perceived barriers to clinical use of pharmacogenomics during participation in an institutional implementation study
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000362
Utility of human leukocyte antigen-B*58: 01 genotyping and patient outcomes
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000359
Gene expression changes in lymphoblastoid cell lines and primary B cells by dexamethasone
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000365
DNA methylation is associated with improvement in lung function on inhaled corticosteroids in pediatric asthmatics
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000366
Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000361
The N680S variant in the follicle-stimulating hormone receptor gene identifies hyperresponders to controlled ovarian stimulation
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000374
Targeted ultra-deep sequencing of a South African Bantu-speaking cohort to comprehensively map and characterize common and novel variants in 65 pharmacologically-related genes
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000380
The effect of the CYP2D6 genotype on the maintenance dose of metoprolol in a chronic Dutch patient population.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000381
Pharmacogeomic implications of population diversity in Latin America: TPMT and NUDT15 polymorphisms and thiopurine dosing
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000388
Effect of tacrolimus dispositional genetics on acute rejection in the first 2 weeks and estimated glomerular filtration rate in the first 3 months following kidney transplantation
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000360
International survey of patients undergoing percutaneous coronary intervention and their attitudes toward pharmacogenetic testing
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000368
Impact of SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of phenylephrine and salbutamol by human SULT1A3 allozymes
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000371
Pharmacogenetic analysis of belimumab fails to identify robust genetic predictors of efficacy in lupus
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000378
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000394
Analysis of comprehensive pharmacogenomic profiling to impact in-hospital prescribing
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000346
PharmGKB summary: sertraline pathway, pharmacokinetics
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000392
The role of phase I and II genetic polymorphisms, smoking, alcohol and cancer family history, in the risk of developing testicular cancer.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000379
The relevance of the individual screening for genetic variants in predicting ovarian response.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/fpc.0000000000000386
Association between HNF4A mutations and bleeding complications in patients with stable international normalized ratio.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000384
HLA-B*58:01 carrier status of Hmong in Minnesota: first in Hmong genotyping for prevalence of this biomarker of risk for severe cutaneous adverse reactions caused by allopurinol
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000391
Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000370
PharmGKB summary: methylphenidate pathway, pharmacokinetics/pharmacodynamics
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000376
Associations between TMEM196 polymorphisms and NSAID-exacerbated respiratory disease in asthma
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000367
Individuals with CYP2C8 and CYP2C9 reduced metabolism haplotypes self-adjusted ibuprofen dose in the Coriell Personalized Medicine Collaborative
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000364
N-acetyltransferase 2 enzyme genotype–phenotype discordances in both HIV-negative and HIV-positive Nigerians
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000373
A multiplex pharmacogenetics assay using the MinION nanopore sequencing device.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/fpc.0000000000000385
PharmGKB summary: very important pharmacogene information for CACNA1S
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000393
Fentanyl overdoses and pharmacogenetics
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000389
PharmGKB summary: Ondansetron and tropisetron pathways, pharmacokinetics and pharmacodynamics
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000369
Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer.
来源期刊:Pharmacogenetics and genomicsDOI:10.1097/FPC.0000000000000382
Enriched developmental biology molecular pathways impact on antipsychotics-induced weight gain
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000390
An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance)
来源期刊:Pharmacogenetics and GenomicsDOI:10.1097/FPC.0000000000000375