Pharmaceutical Development & Technology publishes research on the design, development, manufacture, and evaluation of conventional and novel drug delivery systems, emphasizing practical solutions and applications to theoretical and research-based problems. The journal aims to publish significant, innovative and original research to advance the frontiers of pharmaceutical development and technology. Through original articles, reviews (where prior discussion with the EIC is encouraged), short reports, book reviews and technical notes, Pharmaceutical Development & Technology covers aspects such as: -Preformulation and pharmaceutical formulation studies -Pharmaceutical materials selection and characterization -Pharmaceutical process development, engineering, scale-up and industrialisation, and process validation -QbD in the form a risk assessment and DoE driven approaches -Design of dosage forms and drug delivery systems -Emerging pharmaceutical formulation and drug delivery technologies with a focus on personalised therapies -Drug delivery systems research and quality improvement -Pharmaceutical regulatory affairs This journal will not consider for publication manuscripts focusing purely on clinical evaluations, botanicals, or animal models.
药学发展与技术《药物开发与技术》发表了关于传统和新型药物输送系统的设计、开发、生产和评估的研究,强调理论和研究问题的实际解决方案和应用。《药物开发与技术》通过原创文章、综述(鼓励与EIC事先讨论)、简短报告、书评和技术说明,涵盖以下方面:-预制剂和药物制剂研究-药物材料选择和表征-药物工艺开发、工程、放大和工业化以及工艺验证-以风险评估和DoE驱动方法形式的QbD-剂型和给药系统的设计-以个性化治疗为重点的新兴药物制剂和给药技术-给药系统研究和质量改进-药物监管事务本杂志不考虑出版纯粹关注临床评价、植物药或动物模型的手稿。
Dexamethasone loaded multi-layer poly-l-lactic acid/pluronic P123 composite electrospun nanofiber scaffolds for bone tissue engineering and drug delivery
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1481429
Incorporation of rosuvastatin-loaded chitosan/chondroitin sulfate nanoparticles into a thermosensitive hydrogel for bone tissue engineering: preparation, characterization, and cellular behavior
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1484765
Design, characterization, and evaluation of aceclofenac-loaded Eudragit RS 100 nanoparticulate system for ocular delivery
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1486424
Key production parameters for the development of solid lipid nanoparticles by high shear homogenization
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1647235
Piroxicam cocrystals with phenolic coformers: preparation, characterization, and dissolution properties
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1455210
Development and in vivo evaluation of chitosan nanoparticles for the oral delivery of albumin
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1479867
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1455698
Thermosensitive hydrogel containing sertaconazole loaded nanostructured lipid carriers for potential treatment of fungal keratitis
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1616755
Montelukast nasal spray: formulation development and in vitro evaluation
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1514523
The effect of critical process parameters of the high pressure homogenization technique on the critical quality attributes of flurbiprofen nanosuspensions
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1667384
Development and characterization of octreotide-modified curcumin plus docetaxel micelles for potential treatment of non-small-cell lung cancer
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1647236
Mechanics of tablet formation: a comparative evaluation of percolation theory with classical concepts
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1599913
Evaluation of the losartan solubility in the biowaiver context by shake-flask method and intrinsic dissolution
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1472610
Optimization of a dry powder inhaler of ciprofloxacin-loaded polymeric nanomicelles by spray drying process
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1545237
Evaluation of topical econazole nitrate formulations with potential for treating Raynaud’s phenomenon
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1578371
Revaprazan-loaded surface-modified solid dispersion: physicochemical characterization and in vivo evaluation
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1597114
New in-situ gelling biopolymer-based matrix for bioavailability enhancement of glimepiride; in-vitro/in-vivo x-ray imaging and pharmacodynamic evaluations
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1517366
An evaluation of crude palm oil (CPO) and tocotrienol rich fraction (TRF) of palm oil as percutaneous permeation enhancers using full-thickness human skin
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1509347
Preparation of mesoporous silica microparticles by sol–gel/emulsion route for protein release
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1457051
Formulation of acyclovir-loaded solid lipid nanoparticles: 2. Brain targeting and pharmacokinetic study
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1667386
Dihydroartemisinin and doxorubicin co-loaded Soluplus®-TPGS mixed micelles: formulation characterization, cellular uptake, and pharmacodynamic studies
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1641726
Dexamethasone loaded PLGA nanoparticles for potential local treatment of oral precancerous lesions
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1673407
Transdermal fennel essential oil nanoemulsions with promising hepatic dysfunction healing effect: in vitro and in vivo study
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1584633
Increased in vitro leishmanicidal activity of octyl gallate loaded poly(methyl methacrylate) nanoparticles
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1547747
On the plasticizing properties of divalproex sodium: physicochemical and spectroscopic characterization studies
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1514049
PHBV/PLGA nanoparticles for enhanced delivery of 5-fluorouracil as promising treatment of colon cancer
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1684945
Physico-chemical stability of co-formulation of PEGylated human amylin with insulin
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1621896
Voriconazole incorporated nanofiber formulations for topical application: preparation, characterization and antifungal activity studies against Candida species
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1706563
Enhancement of the intestinal absorption of bortezomib by self-nanoemulsifying drug delivery system
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1699109
Bile acid-polymer-probucol microparticles: protective effect on pancreatic β-cells and decrease in type 1 diabetes development in a murine model
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1665069
Development of a stability-indicating UPLC method for determination of isotretinoin in bulk drug
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1454469
Synergistic effect of polyethylene glycol and superdisintegrant on dissolution rate enhancement of simvastatin in pellet formulation
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1584632
Development and in vivo evaluation of baicalin-loaded W/O nanoemulsion for lymphatic absorption
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1646757
Understanding the impact of magnesium stearate variability on tableting performance using a multivariate modeling approach
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1673774
Development of an optimized febuxostat self-nanoemulsified loaded transdermal film: in-vitro, ex-vivo and in-vivo evaluation
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1700520
Evaluation of paromomycin sulphate permeation using ex vivo human skin model
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1485697
Effect of sulfobutyl ether-β-cyclodextrin and propylene glycol alginate on the solubility of clozapine
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1514521
Assessment of taste masking of captopril by ion-exchange resins using electronic gustatory system
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1687520
Solubilization of the chlorin TPCS2a in the presence of Pluronic® F127/Tween 80 mixtures
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1515955
Ethanol effect on acid resistance of selected enteric polymers
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2017.1412461
Squalane-based emulsion vaccine delivery system: composition with murabutide activate Th1 response
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1469150
Terbinafine-loaded branched PLGA-based cationic nanoparticles with modifiable properties
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1667387
Development of a small-scale spray-drying approach for amorphous solid dispersions (ASDs) screening in early drug development
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2018.1534861
What to consider for a good quality PDE document?
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1592188
Artificial membranes in combination with selected natural oils for in vitro drug passive diffusion screening in Ussing type chamber apparatus applied to gastro-retentive systems
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1705484
Investigation of dissolution rate kinetics of bulk pharmaceutical feed streams within a stirred tank vessel and a twin screw extruder
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1685543
Investigation on the effect of roller compaction on paracetamol
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1676783
Characterization and pharmacokinetic evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1567760
Improved processability of ethambutol hydrochloride by spherical agglomeration
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1705487
Design and characterization of an organogel system containing ascorbic acid microparticles produced with propolis by-product
来源期刊:Pharmaceutical Development and TechnologyDOI:10.1080/10837450.2019.1669643