Immunology is a diverse and growing discipline that can be defined as the study of the tissues, cells and molecules involved in host defence mechanisms. Immunologists attempt to understand how the immune system develops, how the body defends itself against disease, and what happens when it all goes wrong. Nature Reviews Immunology provides in-depth coverage of all areas of immunology, from fundamental mechanisms to applied aspects. Subjects Covered:-Allergy and asthma-Autoimmunity-Antigen processing and presentation-Apoptosis and cell death-Chemokines and chemokine receptors-Cytokines and cytokine receptors-Development and function of cells of the immune system-Haematopoiesis-Infection and immunity-Immunotherapy-Innate immunity-Mucosal immunology and the microbiota-Regulation of the immune response-Signalling in the immune system-Transplantation-Tumour immunology and immunotherapy-Vaccine development
免疫学是一门多样性和不断发展的学科,可以定义为对参与宿主防御机制的组织、细胞和分子的研究。免疫学家试图了解免疫系统是如何发育的,身体是如何抵御疾病的,以及当一切都出了问题时会发生什么。自然评论免疫学提供了从基本机制到应用方面的免疫学的所有领域的深入报道。涵盖的主题:-过敏和哮喘-自身免疫-抗原加工和呈递-细胞凋亡和细胞死亡-趋化因子和趋化因子受体-细胞因子和细胞因子受体-免疫系统细胞的发育和功能-造血-感染和免疫-免疫治疗-先天免疫-粘膜免疫学和微生物-免疫应答的调节-免疫系统中的信号传导-移植-肿瘤免疫学和免疫治疗-疫苗开发
Macrophages as regulators of tumour immunity and immunotherapy
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Defining ‘T cell exhaustion’
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The human antibody response to influenza A virus infection and vaccination
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The gasdermins, a protein family executing cell death and inflammation
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Osteoimmunology: evolving concepts in bone–immune interactions in health and disease
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Metabolic coordination of T cell quiescence and activation
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Pain and immunity: implications for host defence
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Sleep and inflammation: partners in sickness and in health
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Mechanisms underlying T cell ageing
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Immune mechanisms of hypertension
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Sodium in the microenvironment regulates immune responses and tissue homeostasis
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Moving tuberculosis vaccines from theory to practice
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Engineering universal cells that evade immune detection
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Patrolling the vascular borders: platelets in immunity to infection and cancer
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Thymic epithelial cell heterogeneity: TEC by TEC
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B cells still front and centre in immunology
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Genome organization in immune cells: unique challenges
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Do haematopoietic stem cells age?
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Novel connections and precision approaches
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Tumour heterogeneity determines immune response
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Getting enough energy for immunity
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0159-y
The signposts and winding roads to immunity and inflammation
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On macrophage diversity and inflammatory metabolic timers
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Containment strategy
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0122-y
Nervous anticipation
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Cancer immunotherapy goes trispecific
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Pro-tumour programming at the macrophage membrane
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bnAbs for HIV: shepherding towards improbable mutations
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0270-0
Neuronal itaconate restricts viral infection
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Systems-level patterns emerge
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-018-0106-3
Trans-Golgi network breaks away to activate NLRP3
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-018-0111-6
Connecting angiogenesis and autoimmunity
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0217-5
Commensal viruses contribute to gut health
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0241-5
TOX2 helping hand for TFH cells
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0249-x
Antibiotics can impede flu vaccines
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0227-3
Microbiota supports air attack
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0149-0
Joint effort needed
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0242-4
Functional degradation ignites the inflammasome
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0169-9
CD8+ T cells cure without killing
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0150-7
CD28-like role for a Toll
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0171-2
Deciphering the gut–brain link in NEC
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Fast tracking immunity
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Pain killers
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Move to metabolism
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Exercise lowers leptin and leukocytosis
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MS signature TH cell subset
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Middle management of CCR5
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Stromal support from IL-17
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0163-2
Poised plasticity of skin T cells
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Macrophages throw tumour cells a lifeline
来源期刊:Nature Reviews ImmunologyDOI:10.1038/s41577-019-0148-1