Leukemia publishes high quality, peer reviewed research that covers all aspects of the research and treatment of leukemia and allied diseases. Studies of normal hemopoiesis are covered because of their comparative relevance.Topics of interest include oncogenes, growth factors, stem cells, leukemia genomics, cell cycle, signal transduction, molecular targets for therapy and more.We publish a range of content types including original research articles, reviews, letters, correspondence and comments that elaborate on significant advances in the field and cover topical issues.
白血病出版高质量的,同行评审的研究,涵盖了白血病和相关疾病的研究和治疗的所有方面。由于正常造血的相关性,我们的研究也被包括在内。我们感兴趣的主题包括致癌基因、生长因子、干细胞、白血病基因组学、细胞周期、信号转导、治疗的分子靶点等。我们发表了一系列内容类型,包括原创研究文章、综述、信件、通信和评论,详细阐述了该领域的重大进展,并涵盖了热点问题。
Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study
来源期刊:LeukemiaDOI:10.1038/s41375-019-0602-x
Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling
来源期刊:LeukemiaDOI:10.1038/s41375-019-0473-1
How we use venetoclax with hypomethylating agents for the treatment of newly diagnosed patients with acute myeloid leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0612-8
CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages
来源期刊:LeukemiaDOI:10.1038/s41375-019-0463-3
Clinical, histopathological and molecular characterization of hypoplastic myelodysplastic syndrome
来源期刊:LeukemiaDOI:10.1038/s41375-019-0457-1
Chronic myeloid leukemia stem cells
来源期刊:LeukemiaDOI:10.1038/s41375-019-0490-0
S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes
来源期刊:LeukemiaDOI:10.1038/s41375-019-0397-9
Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis
来源期刊:LeukemiaDOI:10.1038/s41375-019-0450-8
LAMP2 expression dictates azacytidine response and prognosis in MDS/AML
来源期刊:LeukemiaDOI:10.1038/s41375-018-0336-1
Prognostic impact of RAS-pathway mutations in patients with myelofibrosis
来源期刊:LeukemiaDOI:10.1038/s41375-019-0603-9
The WNT receptor ROR2 drives the interaction of multiple myeloma cells with the microenvironment through AKT activation
来源期刊:LeukemiaDOI:10.1038/s41375-019-0486-9
Recurrent PDGFRB mutations in unicentric Castleman disease
来源期刊:LeukemiaDOI:10.1038/s41375-018-0323-6
The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution
来源期刊:LeukemiaDOI:10.1038/s41375-019-0479-8
The mechanistic study behind suppression of GVHD while retaining GVL activities by myeloid-derived suppressor cells.
来源期刊:LeukemiaDOI:10.1038/s41375-019-0394-z
A revised international prognostic score system for Waldenström’s macroglobulinemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0431-y
Familial myeloid malignancies with germline TET2 mutation
来源期刊:LeukemiaDOI:10.1038/s41375-019-0675-6
The first-in-human study of the pan-PIM kinase inhibitor PIM447 in patients with relapsed and/or refractory multiple myeloma
来源期刊:LeukemiaDOI:10.1038/s41375-019-0482-0
CXCR5+CD8+ T cells are a distinct functional subset with antitumor activity
来源期刊:LeukemiaDOI:10.1038/s41375-019-0464-2
Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma
来源期刊:LeukemiaDOI:10.1038/s41375-019-0396-x
Telomere length predicts for outcome to FCR chemotherapy in CLL
来源期刊:LeukemiaDOI:10.1038/s41375-019-0389-9
Rethinking clinical trial endpoints in myelodysplastic syndromes
来源期刊:LeukemiaDOI:10.1038/s41375-018-0367-7
Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0596-4
Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome
来源期刊:LeukemiaDOI:10.1038/s41375-019-0514-9
Humanized CD19-specific chimeric antigen-receptor T-cells in 2 adults with newly diagnosed B-cell acute lymphoblastic leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0516-7
Prognostic index for patients with relapsed or refractory acute myeloid leukemia who underwent hematopoietic cell transplantation: a KSGCT multicenter analysis
来源期刊:LeukemiaDOI:10.1038/s41375-019-0494-9
Integrative phosphoproteome and interactome analysis of the role of Ubash3b in BCR-ABL signaling
来源期刊:LeukemiaDOI:10.1038/s41375-019-0535-4
PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion
来源期刊:LeukemiaDOI:10.1038/s41375-019-0428-6
Intracellular expression of FLT3 in Purkinje cells: implications for adoptive T-cell therapies
来源期刊:LeukemiaDOI:10.1038/s41375-018-0330-7
An MDS-specific frailty index based on cumulative deficits adds independent prognostic information to clinical prognostic scoring
来源期刊:LeukemiaDOI:10.1038/s41375-019-0666-7
Early hospital discharge after intensive induction chemotherapy for adults with acute myeloid leukemia or other high-grade myeloid neoplasm
来源期刊:LeukemiaDOI:10.1038/s41375-019-0586-6
Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0458-0
Randomized assessment of delayed intensification and two methods for parenteral methotrexate delivery in childhood B-ALL: Children’s Oncology Group Studies P9904 and P9905
来源期刊:LeukemiaDOI:10.1038/s41375-019-0642-2
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance
来源期刊:LeukemiaDOI:10.1038/s41375-019-0619-1
Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes
来源期刊:LeukemiaDOI:10.1038/s41375-019-0509-6
Prognostic restaging at the time of second-line therapy in patients with AL amyloidosis
来源期刊:LeukemiaDOI:10.1038/s41375-019-0400-5
Molecular characterization of a second myeloid neoplasm developing after treatment for acute myeloid leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0633-3
Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes
来源期刊:LeukemiaDOI:10.1038/s41375-019-0623-5
Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice
来源期刊:LeukemiaDOI:10.1038/s41375-019-0577-7
The BET Inhibitor GS-5829 Targets Chronic Lymphocytic Leukemia Cells and Their Supportive Microenvironment
来源期刊:LeukemiaDOI:10.1038/s41375-019-0682-7
The impact of anti-thymocyte globulin on the outcomes of Patients with AML with or without measurable residual disease at the time of allogeneic hematopoietic cell transplantation
来源期刊:LeukemiaDOI:10.1038/s41375-019-0631-5
Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML
来源期刊:LeukemiaDOI:10.1038/s41375-019-0415-y
Comparison of minimal residual disease levels in bone marrow and peripheral blood in adult acute lymphoblastic leukemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0599-1
Dichotomous Toll-like receptor responses in chronic lymphocytic leukemia patients under ibrutinib treatment
来源期刊:LeukemiaDOI:10.1038/s41375-018-0335-2
Recommendations for cytogenomic analysis of hematologic malignancies: comments from the Francophone Group of Hematological Cytogenetics (GFCH)
来源期刊:LeukemiaDOI:10.1038/s41375-019-0696-1
On the road to molecular prognostication in SMM
来源期刊:LeukemiaDOI:10.1038/s41375-019-0627-1
Unexpected variation in leukemia stem cell frequency and genetic heterogeneity in two murine leukemia models initiated by AML1/ETO9a and CALM/AF10
来源期刊:LeukemiaDOI:10.1038/s41375-019-0657-8
Correction: Early myeloma-related death in elderly patients: development of a clinical prognostic score and evaluation of response sustainability role
来源期刊:LeukemiaDOI:10.1038/s41375-019-0408-x
Carfilzomib-induced reticulocytosis in patients with multiple myeloma is caused by impaired terminal erythroid maturation
来源期刊:LeukemiaDOI:10.1038/s41375-019-0565-y
Clonal hematopoiesis by SLIT1-mutated hematopoietic stem cells due to a breakdown of the autocrine loop involving Slit1 in acquired aplastic anemia
来源期刊:LeukemiaDOI:10.1038/s41375-019-0510-0
Hematopoietic stem cell transplantation for adults with T-cell lymphoblastic lymphoma: can we successfully step into the era of precision medicine?
来源期刊:LeukemiaDOI:10.1038/s41375-019-0608-4