The Journal of Lipid Research (JLR) publishes original articles and reviews in the broadly defined area of biological lipids. We encourage the submission of manuscripts relating to lipids, including those addressing problems in biochemistry, molecular biology, structural biology, cell biology, genetics, molecular medicine, clinical medicine and metabolism. Major criteria for acceptance of articles are new insights into mechanisms of lipid function and metabolism and/or genes regulating lipid metabolism along with sound primary experimental data. Interpretation of the data is the authors’ responsibility, and speculation should be labeled as such. Manuscripts that provide new ways of purifying, identifying and quantifying lipids are invited for the Methods section of the Journal. JLR encourages contributions from investigators in all countries, but articles must be submitted in clear and concise English.
《脂质研究杂志》(JLR)在广泛定义的生物脂质领域发表原创文章和评论。我们鼓励提交与脂质相关的手稿,包括解决生物化学、分子生物学、结构生物学、细胞生物学、遗传学、分子医学、临床医学和代谢问题的手稿。接受文章的主要标准是对脂质功能和代谢机制和/或调控脂质代谢的基因的新见解沿着可靠的原始实验数据。对数据的解释是作者的责任,推测应该被贴上这样的标签。提供新的纯化、鉴定和定量脂质的方法的手稿被邀请加入本杂志的方法部分。捷豹路虎鼓励来自所有国家的研究者投稿,但文章必须以清晰简洁的英语提交。
Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.R094060
It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.S091843
Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.S091181
Mammalian lipin phosphatidic acid phosphatases in lipid synthesis and beyond: metabolic and inflammatory disorders
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.S091769
Therapeutic FGF19 promotes HDL biogenesis and transhepatic cholesterol efflux to prevent atherosclerosis[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M089961
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000177
Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M092551
Metabolism of cholesterol and progesterone is differentially regulated in primary trophoblastic subtypes and might be disturbed in recurrent miscarriages[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.P093427
Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000154
Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M089789
Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000419
Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.TR119000267
Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093351
SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000119
11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M092908
Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.D090571
Lipid rafts and pathogens: the art of deception and exploitation
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.TR119000391
Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.P119000335
Rosiglitazone remodels the lipid droplet and britens human visceral and subcutaneous adipocytes ex vivo[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M091173
Plasma membrane asymmetry of lipid organization: fluorescence lifetime microscopy and correlation spectroscopy analysis[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.D119000364
CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β-cateninT120/TCF21 pathway
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000100
ACBD6 protein controls acyl chain availability and specificity of the N-myristoylation modification of proteins[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M091397
Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093229
1H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M092643
Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000399
Long and very long lamellar phases in model stratum corneum lipid membranes.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.M090977
Angiotensinogen in hepatocytes contributes to Western diet-induced liver steatosis[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093252
Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000346
Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.P094433
Effect of fatty acids on melanogenesis and tumor cell growth in melanoma cells[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M090712
Nonsynonymous SNPs in LPA homologous to plasminogen deficiency mutants represent novel null apo(a) alleles[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M094540
Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000420
Uptake and metabolism of β-apo-8′-carotenal, β-apo-10′-carotenal, and β-apo-13-carotenone in Caco-2 cells
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093161
A new method for measuring cholesterol efflux capacity uses stable isotope-labeled, not radioactive-labeled, cholesterol[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.D086884
Overexpression of Nudt7 decreases bile acid levels and peroxisomal fatty acid oxidation in the liver.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.M092676
Plasma oxyphytosterol concentrations are not associated with CVD status in Framingham Offspring Study participants[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.RA119000274
Regulatory T cells suppress excessive lipid accumulation in alcoholic liver disease.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.M083568
Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.D091470
Investigation of diagnostic performance of five urinary cholesterol metabolites for Niemann-Pick disease type C[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093971
DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.M090951
Anti-parasitic drug discovery takes a giant leap forward1
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.C094250
Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M089367
AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M092494
The PQ-loop protein Any1 segregates Drs2 and Neo1 functions required for viability and plasma membrane phospholipid asymmetry[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M093526
Repression of hepatocyte nuclear factor 4 alpha by AP-1 underlies dyslipidemia associated with retinoic acid[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.M088880
Functional recombinant apolipoprotein A5 that is stable at high concentrations at physiological pH[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.D119000103
Advances in determining signaling mechanisms of ceramide and role in disease.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.S092874
Metabolomic correlates of central adiposity and earlier-life body mass index[S]
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.P085944
LPA receptor 4 deficiency attenuates experimental atherosclerosis.
来源期刊:Journal of lipid researchDOI:10.1194/jlr.M091066
Withdrawal: Regulatory T cells suppress excessive lipid accumulation in alcoholic liver disease
来源期刊:Journal of Lipid ResearchDOI:10.1194/jlr.w119000540