The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality.The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research.All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
Spandidos Publications的主要目标是以清晰、简洁和客观的方式促进科学交流，同时努力提供高质量原创作品的及时出版。期刊主要集中在分子和实验医学、肿瘤学、临床和实验癌症治疗以及生物医学研究。Spandidos Publications有限公司出版的所有期刊均保持最高的质量标准。其编辑委员会成员都是世界著名的科学家。
From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment (Review)
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2018.4661
Cancer-associated stroke: Pathophysiology, detection and management (Review)
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4669
Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial-mesenchymal transition mediated by the FAK/AKT/MMPs axis
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2018.4607
lncRNA SNHG16 is associated with proliferation and poor prognosis of pediatric neuroblastoma
来源期刊：International Journal of OncologyDOI：10.3892/IJO.2019.4813
Icariin enhances the chemosensitivity of cisplatin‑resistant ovarian cancer cells by suppressing autophagy via activation of the AKT/mTOR/ATG5 pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4785
EGFR mutation decreases FDG uptake in non‑small cell lung cancer via the NOX4/ROS/GLUT1 axis.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2018.4626
Downregulation of protein disulfide‑isomerase A3 expression inhibits cell proliferation and induces apoptosis through STAT3 signaling in hepatocellular carcinoma.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4710
Phospho-STAT1 expression as a potential biomarker for anti-PD-1/anti-PD-L1 immunotherapy for breast cancer
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4779
Silencing of COPB2 inhibits the proliferation of gastric cancer cells and induces apoptosis via suppression of the RTK signaling pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4717
Role of tumor‑derived extracellular vesicles in cancer progression and their clinical applications (Review).
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4745
Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4700
Comparison of tumor-targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4712
FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4721
Bile acids promote gastric intestinal metaplasia by upregulating CDX2 and MUC2 expression via the FXR/NF-κB signalling pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4692
A novel mechanism for the anticancer activity of aspirin and salicylates
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4701
Diverse and cancer type-specific roles of the p53 R248Q gain-of-function mutation in cancer migration and invasiveness
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4723
2,3,7,8-tetrachlorodibenzo-p-dioxin suppresses the growth of human colorectal cancer cells in vitro: Implication of the aryl hydrocarbon receptor signaling
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4703
Selective uveal melanoma inhibition with calcium channel blockade
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4873
Targeting retinoblastoma protein phosphorylation in combination with EGFR inhibition in pancreatic cancer cells
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2018.4658
MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4928
Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4787
Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4796
Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4816
Upregulation of microRNA-194-5p inhibits hypopharyngeal carcinoma cell proliferation, migration and invasion by targeting SMURF1 via the mTOR signaling pathway
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4711
Genome-wide investigation of the clinical implications and molecular mechanism of long noncoding RNA LINC00668 and protein-coding genes in hepatocellular carcinoma
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4858
Role of evaluating tumor‑infiltrating lymphocytes, programmed death‑1 ligand 1 and mismatch repair proteins expression in malignant mesothelioma.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4883
Harmine induces anticancer activity in breast cancer cells via targeting TAZ
来源期刊：International Journal of OncologyDOI：10.3892/IJO.2019.4777
Re‑irradiation plus hyperthermia for recurrent pediatric sarcoma; a simulation study to investigate feasibility.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2018.4622
HOXA6 inhibits cell proliferation and induces apoptosis by suppressing the PI3K/Akt signaling pathway in clear cell renal cell carcinoma
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4789
Population and single-cell transcriptome analyses reveal diverse transcriptional changes associated with radioresistance in esophageal squamous cell carcinoma
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4897
Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4725
Evaluation of pro‑ and anti‑tumor effects induced by three colony‑stimulating factors, G‑CSF, GM‑CSF and M‑CSF, in bladder cancer cells: Is G‑CSF a friend of bladder cancer cells?
来源期刊：International journal of oncologyDOI：10.3892/IJO.2019.4772
Link between spermine oxidase and apoptosis antagonizing transcription factor: A new pathway in neuroblastoma.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4878
Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4741
8‑Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4934
ERp57‑small interfering RNA silencing can enhance the sensitivity of drug‑resistant human ovarian cancer cells to paclitaxel.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2018.4628
Interaction of YAP1 and mTOR promotes bladder cancer progression
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4922
Cellular and molecular alterations induced by low-dose fisetin in human chronic myeloid leukemia cells
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4889
ATAD2 predicts poor outcomes in patients with ovarian cancer and is a marker of proliferation
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4913
Genome profiling revealed the activation of IL2RG/JAK3/STAT5 in peripheral T-cell lymphoma expressing the ITK-SYK fusion gene
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4882
S100A8 facilitates cholangiocarcinoma metastasis via upregulation of VEGF through TLR4/NF-κB pathway activation
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4907
Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4797
17β-estradiol-induced mitochondrial dysfunction and Warburg effect in cervical cancer cells allow cell survival under metabolic stress
来源期刊：International Journal of OncologyDOI：10.3892/ijo.2019.4912
HBx‑associated long non‑coding RNA activated by TGF‑β promotes cell invasion and migration by inducing autophagy in primary liver cancer.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4908
Reversine induces cell cycle arrest and apoptosis via upregulation of the Fas and DR5 signaling pathways in human colorectal cancer cells.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4746
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4
来源期刊：International Journal of OncologyDOI：10.3892/IJO.2019.4786
Long non‑coding RNAs in HBV‑related hepatocellular carcinoma (Review).
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4909
Characterization of the human zinc finger nfx‑1‑type containing 1 encoding ZNFX1 gene and its response to 12‑O‑tetradecanoyl‑13‑acetate in HL‑60 cells.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4860
Roles of FGF8 subfamily in embryogenesis and oral‑maxillofacial diseases (Review).
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4677
Eya2 is critical for the E2A‑HLF‑mediated immortalization of mouse hematopoietic stem/progenitor cells.
来源期刊：International journal of oncologyDOI：10.3892/ijo.2019.4673
