Expert Opinion on Drug Discovery (ISSN 1746-0441 [print], 1746-045X [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles on novel technologies involved in the drug discovery process, leading to new leads and reduced attrition rates. Each article is structured to incorporate the author’s own expert opinion on the scope for future development.The Editors welcome:Reviews covering chemoinformatics; bioinformatics; assay development; novel screening technologies; in vitro/in vivo models; structure-based drug design; systems biologyDrug Case Histories examining the steps involved in the preclinical and clinical development of a particular drugThe audience consists of scientists and managers in the healthcare and pharmaceutical industry, academic pharmaceutical scientists and other closely related professionals looking to enhance the success of their drug candidates through optimisation at the preclinical level.
药物发现专家意见（ISSN 1746-0441 [印刷版]，1746- 045 X [电子版]）是一份MEDLINE索引、同行评审的国际期刊，发表了关于药物发现过程中所涉及的新技术的综述文章，这些新技术导致了新的线索并降低了损耗率。每一篇文章的结构都结合了作者自己对未来发展范围的专家意见。生物信息学;分析开发;新型筛选技术;体外/体内模型;基于结构的药物设计;系统生物学研究特定药物的临床前和临床开发步骤的药物案例历史受众包括医疗保健和制药行业的科学家和管理人员、学术制药科学家和其他密切相关的专业人员，他们希望通过临床前水平的优化来提高候选药物的成功率。
Broad-spectrum coronavirus antiviral drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1581171
Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1651289
Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1704729
Are we seeing a resurgence in the use of natural products for new drug discovery?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1582639
The compromise of virtual screening and its impact on drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1604677
DataWarrior: an evaluation of the open-source drug discovery tool
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1581170
Future challenges with DNA-encoded chemical libraries in the drug discovery domain
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1614559
Recent developments in biological aspects of chalcones: the odyssey continues
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1573812
Animal models of ischemic stroke and their impact on drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1573984
Binding affinity in drug design: experimental and computational techniques
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1623202
Novel approaches to the discovery of selective human monoamine oxidase-B inhibitors: is there room for improvement?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1637415
A bright future for fragment-based drug discovery: what does it hold?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1583643
Why hasn’t there been more progress in new Chagas disease drug discovery?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1681394
Novel antiviral drug discovery strategies to tackle drug-resistant mutants of influenza virus strains
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1560261
Toward the identification of ZDHHC enzymes required for palmitoylation of viral protein as potential drug targets
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1696306
An outlook on using serial femtosecond crystallography in drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1626822
Advances in preclinical approaches to Chagas disease drug discovery
来源期刊：Expert opinion on drug discoveryDOI：10.1080/17460441.2019.1652593
Current developments in lantibiotic discovery for treating Clostridium difficile infection
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1549032
Omics of antimicrobials and antimicrobial resistance
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1588880
Exciting advances in GPCR-based drugs discovery for treating metabolic disease and future perspectives
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1583642
Fragment-based screening with natural products for novel anti-parasitic disease drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1653849
Considerations for future tau-targeted therapeutics: can they deliver?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1685977
Do animal models hold value in Autism spectrum disorder (ASD) drug discovery?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1621285
Animal models for modeling pancreatic cancer and novel drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1566319
Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1614560
Drugs that target aging: how do we discover them?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1597049
Successes, failures, and future prospects of prodrugs and their clinical impact
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1567487
A new wave of innovation in Semantic web tools for drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1586880
Halogen bonding in halocarbon-protein complexes and computational tools for rational drug design
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1619692
Computational re-design of protein structures to improve solubility
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1637413
Are academic drug discovery efforts receiving more recognition with declining industry efficiency?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1596080
Is one-shot learning a viable option in drug discovery?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1593368
Animal models of major depressive disorder and the implications for drug discovery and development
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1575360
Dealing with frequent hitters in drug discovery: a multidisciplinary view on the issue of filtering compounds on biological screenings
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1654453
Using Xenopus oocytes in neurological disease drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1682993
Recent advances from metabolomics and lipidomics application in alzheimer’s disease inspiring drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1674808
Recent advances in computational design of potent aromatase inhibitors: open-eye on endocrine-resistant breast cancers
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1646245
The identification of small molecules that stimulate retinal pigment epithelial cells: potential novel therapeutic options for treating retinopathies
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1559148
Can 4D bioprinting revolutionize drug development?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1636781
Lenvatinib for thyroid cancer treatment: discovery, pre-clinical development and clinical application
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1674280
Are animal models a necessity for acute radiation syndrome drug discovery?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1591364
Current discovery strategies for hepatocellular carcinoma therapeutics
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1696769
Modeling heart failure in animal models for novel drug discovery and development
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1582636
Is anti-ageing drug discovery becoming a reality?
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1702965
Drug design strategies with metal-hydroxyquinoline complexes
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1702964
Contemporary medicinal-chemistry strategies for discovery of blood coagulation factor Xa inhibitors
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1626821
Using miniature brain implants in rodents for novel drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1577816
Transforming cancer drug discovery with Big Data and AI
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1637414
How to utilize academic research efforts in cancer drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2019.1582637
Emerging opportunities of exploiting mycobacterial electron transport chain pathway for drug-resistant tuberculosis drug discovery
来源期刊：Expert Opinion on Drug DiscoveryDOI：10.1080/17460441.2020.1696771
