Cancer Gene Therapy is the essential gene and cellular therapy resource for cancer researchers and clinicians, keeping readers up to date with the latest developments in gene and cellular therapies for cancer. The journal publishes original laboratory and clinical research papers, case reports and review articles. Publication topics include RNAi approaches, drug resistance, hematopoietic progenitor cell gene transfer, cancer stem cells, cellular therapies, homologous recombination, ribozyme technology, antisense technology, tumor immunotherapy and tumor suppressors, translational research, cancer therapy, gene delivery systems (viral and non-viral), anti-gene therapy (antisense, siRNA & ribozymes), apoptosis; mechanisms and therapies, vaccine development, immunology and immunotherapy, DNA synthesis and repair.Cancer Gene Therapy publishes the results of laboratory investigations, preclinical studies, and clinical trials in the field of gene transfer/gene therapy and cellular therapies as applied to cancer research. Types of articles published include original research articles; case reports; brief communications; review articles in the main fields of drug resistance/sensitivity, gene therapy, cellular therapy, tumor suppressor and anti-oncogene therapy, cytokine/tumor immunotherapy, etc.; industry perspectives; and letters to the editor.
癌症基因治疗是癌症研究人员和临床医生必不可少的基因和细胞治疗资源，使读者了解癌症基因和细胞治疗的最新进展。该杂志发表原创实验室和临床研究论文、病例报告和综述文章。发表主题包括RNAi方法、耐药性、造血祖细胞基因转移、癌症干细胞、细胞疗法、同源重组、核酶技术、反义技术、肿瘤免疫疗法和肿瘤抑制剂、转化研究、癌症治疗、基因递送系统（病毒和非病毒）、反基因疗法（反义、siRNA和核酶）、细胞凋亡;机制和治疗、疫苗开发、免疫学和免疫治疗、DNA合成和修复。2癌症基因治疗发表实验室研究、临床前研究和临床试验的结果，在基因转移/基因治疗和细胞治疗领域应用于癌症研究。发表的文章类型包括原创研究文章;病例报告;简短通信;综述耐药/敏感性、基因治疗、细胞治疗、肿瘤抑制和抑癌基因治疗、细胞因子/肿瘤免疫治疗等主要领域的文章;行业观点;和给编辑的信。
c-Myc induced upregulation of long non-coding RNA SNHG16 enhances progression and carcinogenesis in oral squamous cell carcinoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0072-8
JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0074-6
Identification of leukemia stem cell expression signatures through Monte Carlo feature selection strategy and support vector machine
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0105-y
PROM1 and PROM2 expression differentially modulates clinical prognosis of cancer: a multiomics analysis
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0109-7
Human marrow stromal cells secrete microRNA-375-containing exosomes to regulate glioma progression
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0079-9
Dissecting the functional role of microRNA 21 in osteosarcoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0092-z
Synergistic antitumor effect on cervical cancer by rational combination of PD1 blockade and CRISPR-Cas9-mediated HPV knockout
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0131-9
High expression of UBE2T predicts poor prognosis and survival in multiple myeloma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0070-x
Overexpression of BMP1 reflects poor prognosis in clear cell renal cell carcinoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0107-9
HITM-SIR: phase Ib trial of intraarterial chimeric antigen receptor T-cell therapy and selective internal radiation therapy for CEA+ liver metastases
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0104-z
Alkaliptosis: a new weapon for cancer therapy
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0134-6
Liposomal delivery of CRISPR/Cas9
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0141-7
MicroRNA-4268 inhibits cell proliferation via AKT/JNK signalling pathways by targeting Rab6B in human gastric cancer
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0118-6
Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0081-2
Autologous CD19-directed chimeric antigen receptor-T cell is an effective and safe treatment to refractory or relapsed diffuse large B-cell lymphoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0073-7
Transferrin receptor-involved HIF-1 signaling pathway in\n cervical cancer
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0078-x
BAG3 regulates multiple myeloma cell proliferation through FOXM1/Rb/E2F axis
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0154-2
Oncolytic activity of HF10 in head and neck squamous cell carcinomas
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0129-3
MicroRNA-200 family expression analysis in metastatic clear cell renal cell carcinoma patients
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0149-z
Translatable gene therapy for lung cancer using Crispr CAS9—an exploratory review
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0116-8
Enhanced antitumor efficacy of an oncolytic adenovirus armed with an EGFR-targeted BiTE using menstrual blood-derived mesenchymal stem cells as carriers
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0110-1
Safety and efficacy of oncolytic HSV-1 G207 inoculated into the cerebellum of mice
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0091-0
Overexpression of SOCS3 mediated by adenovirus vector in mouse and human castration-resistant prostate cancer cells increases the sensitivity to NK cells in vitro and in vivo
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0075-5
PLK1 promotes proliferation and suppresses apoptosis of renal cell carcinoma cells by phosphorylating MCM3
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0094-x
High IFITM3 expression predicts adverse prognosis in acute myeloid leukemia
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0093-y
Specific glioblastoma multiforme prognostic-subtype distinctions based on DNA methylation patterns
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0142-6
Circular RNAs: epigenetic regulators in cancerous and noncancerous skin diseases
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0130-x
Schwannoma gene therapy by adeno-associated virus delivery of\n the pore-forming protein Gasdermin-D
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0077-3
Viral vector: potential therapeutic for glioblastoma multiforme
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0124-8
GATA3 suppresses human fibroblasts-induced metastasis of clear cell renal cell carcinoma via an anti-IL6/STAT3 mechanism
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0146-2
Notch pathway in ependymoma RELA-fused subgroup: upregulation and association with cancer stem cells markers expression
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0122-x
SGPL1321 mutation: one main trigger for invasiveness of pediatric alveolar rhabdomyosarcoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0132-8
CMV enhancer may not be suitable for tissue-specific enhancement of promoters in cancer gene therapy
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0106-x
The role of phosphorylation of MLF2 at serine 24 in BCR-ABL leukemogenesis
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0152-4
Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0138-2
Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0101-2
Prognosis value of RBBP8 expression in plasma cell myeloma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0069-3
Phase I Neoadjuvant Study of Intravesical Recombinant Fowlpox-GM-CSF (rF-GMCSF) or Fowlpox-TRICOM (rF-TRICOM) in Patients with Bladder Carcinoma
来源期刊：Cancer gene therapyDOI：10.1038/s41417-019-0112-z
Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-018-0076-4
Interleukin-17A polymorphisms predict the response and development of tolerance to FOLFOX chemotherapy in colorectal cancer treatment
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0102-1
Correction to: Schwannoma gene therapy by adeno-associated virus\ndelivery of the pore-forming protein Gasdermin-D
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0096-8
Retraction Note: Enhanced suppression of tumor growth using a combination of NK4 plasmid DNA-PEG engrafted cationized dextran complex and ultrasound irradiation
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0148-0
CTGF expression is indicative\n of better survival rates in patients with medulloblastoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0100-3
Identification of genes of four malignant tumors and a novel prediction model development based on PPI data and support vector machines
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0143-5
Application of RNA Sequencing to identify transcriptome modification by DCLK1 in Colorectal Cancer Cells
来源期刊：Cancer gene therapyDOI：10.1038/s41417-019-0144-4
Author Correction: BET inhibitor I-BET151 sensitizes GBM cells to temozolomide via PUMA induction
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0082-1
A qualitative transcriptional signature for determining the grade of colorectal adenocarcinoma
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0139-1
Cancer immunotherapy using the Fusion gene of Sendai virus
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0126-6
HJURP knockdown disrupts clonogenic capacity and increases radiation-induced cell death of glioblastoma cells
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0103-0
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells
来源期刊：Cancer Gene TherapyDOI：10.1038/s41417-019-0153-3
