CANCER BIOLOGY & THERAPY

癌症生物学与治疗

CANCER BIOL THER

影响因子：4.6

JCR分区：Q1

新锐分区：医学2区

是否综述期刊：N/A

是否预警：不在预警名单内

是否OA：否

出版国家/地区：UNITED STATES

出版社：Landes Bioscience

发刊时间：2002

收录数据库：SCIE/Scopus收录/DOAJ开放期刊

ISSN：1538-4047

期刊介绍

Cancer, the second leading cause of death, is a heterogenous group of over 100 diseases. Cancer is characterized by disordered and deregulated cellular and stromal proliferation accompanied by reduced cell death with the ability to survive under stresses of nutrient and growth factor deprivation, hypoxia, and loss of cell-to-cell contacts. At the molecular level, cancer is a genetic disease that develops due to the accumulation of mutations over time in somatic cells. The phenotype includes genomic instability and chromosomal aneuploidy that allows for acceleration of genetic change. Malignant transformation and tumor progression of any cell requires immortalization, loss of checkpoint control, deregulation of growth, and survival. A tremendous amount has been learned about the numerous cellular and molecular genetic changes and the host-tumor interactions that accompany tumor development and progression. It is the goal of the field of Molecular Oncology to use this knowledge to understand cancer pathogenesis and drug action, as well as to develop more effective diagnostic and therapeutic strategies for cancer. This includes preventative strategies as well as approaches to treat metastases. With the availability of the human genome sequence and genomic and proteomic approaches, a wealth of tools and resources are generating even more information. The challenge will be to make biological sense out of the information, to develop appropriate models and hypotheses and to translate information for the clinicians and the benefit of their patients. Cancer Biology & Therapy aims to publish original research on the molecular basis of cancer, including articles with translational relevance to diagnosis or therapy. We will include timely reviews covering the broad scope of the journal. The journal will also publish op-ed pieces and meeting reports of interest. The goal is to foster communication and rapid exchange of information through timely publication of important results using traditional as well as electronic formats. The journal and the outstanding Editorial Board will strive to maintain the highest standards for excellence in all activities to generate a valuable resource.

癌症是死亡的第二大原因，是由100多种疾病组成的异质组。癌症的特征在于细胞和基质增殖紊乱和失调，伴随着细胞死亡减少，具有在营养和生长因子剥夺、缺氧和细胞间接触丧失的应激下存活的能力。在分子水平上，癌症是一种遗传疾病，是由于体细胞中突变随着时间的推移而积累而发展起来的。表型包括基因组不稳定性和染色体非整倍性，这使得遗传变化加速。任何细胞的恶性转化和肿瘤进展都需要永生化、检查点控制的丧失、生长失调和存活。关于伴随肿瘤发生和发展的许多细胞和分子遗传变化以及宿主-肿瘤相互作用，已经了解了大量信息。分子肿瘤学领域的目标是利用这些知识来理解癌症发病机制和药物作用，以及开发更有效的癌症诊断和治疗策略。这包括预防策略以及治疗转移的方法。随着人类基因组序列以及基因组和蛋白质组学方法的可用性，大量的工具和资源正在产生更多的信息。挑战将是从信息中获得生物学意义，开发适当的模型和假设，并为临床医生和患者的利益翻译信息。《癌症生物学与治疗》旨在发表关于癌症分子基础的原创研究，包括与诊断或治疗相关的翻译文章。我们将包括及时审查涵盖广泛的范围内的杂志。该杂志还将发表感兴趣的专栏文章和会议报告。目标是通过使用传统和电子格式及时公布重要结果，促进沟通和信息的快速交流。该杂志和杰出的编辑委员会将努力保持最高标准的卓越的所有活动，以产生宝贵的资源。

年发文量 110

国人发稿量 60.5

国人发文占比 0.55%

自引率 0%

平均录取率约50%

平均审稿周期平均2.3月

版面费 -

偏重研究方向医学-肿瘤学

期刊官网 http://www.tandfonline.com/loi/kcbt20#.V4he8kz9cSQ

投稿链接 https://www.editorialmanager.com/CBT