The Official Journal of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)Clinica Chimica Acta is a high-quality journal which publishes original Research Communications in the field of clinical chemistry and laboratory medicine, defined as the diagnostic application of chemistry, biochemistry, immunochemistry, biochemical aspects of hematology, toxicology, and molecular biology to the study of human disease in body fluids and cells.The objective of the journal is to publish novel information leading to a better understanding of biological mechanisms of human diseases, their prevention, diagnosis, and patient management. Reports of an applied clinical character are also welcome. Papers concerned with normal metabolic processes or with constituents of normal cells or body fluids, such as reports of experimental or clinical studies in animals, are only considered when they are clearly and directly relevant to human disease. Evaluation of commercial products have a low priority for publication, unless they are novel or represent a technological breakthrough. Studies dealing with effects of drugs and natural products and studies dealing with the redox status in various diseases are not within the journal's scope. Development and evaluation of novel analytical methodologies where applicable to diagnostic clinical chemistry and laboratory medicine, including point-of-care testing, and topics on laboratory management and informatics will also be considered. Studies focused on emerging diagnostic technologies and (big) data analysis procedures including digitalization, mobile Health, and artificial Intelligence applied to Laboratory Medicine are also of interest.
国际临床化学和实验室医学联合会官方杂志(IFCC)Clinica Chimica Acta是一本高质量的期刊,发表临床化学和实验室医学领域的原创研究通讯,定义为化学、生物化学、免疫化学、血液学生物化学方面的诊断应用、毒理学和分子生物学等学科,致力于研究体液和细胞中的人类疾病。该杂志的目标是发表新的信息,从而更好地理解人类疾病的生物学机制,预防,诊断和病人管理。应用临床特征的报告也是受欢迎的。与正常代谢过程或正常细胞或体液成分有关的论文,如动物实验或临床研究报告,只有在与人类疾病明确和直接相关时才予以考虑。商业产品的评价具有较低的出版优先级,除非它们是新颖的或代表技术突破。有关药物和天然产物作用的研究以及有关各种疾病中氧化还原状态的研究不在该杂志的范围之内。还将考虑开发和评价适用于诊断临床化学和实验室医学的新型分析方法,包括床旁检测,以及实验室管理和信息学主题。关注新兴诊断技术和(大)数据分析程序(包括数字化、移动的健康和应用于实验室医学的人工智能)的研究也很有意义。
Extracellular vesicles and energy metabolism.
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2018.10.044
Mitochondrial dysfunction in diabetic kidney disease.
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.07.005
Extracellular vesicles in vascular calcification.
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.09.002
Deoxythymidylate kinase, DTYMK, is a novel gene for mitochondrial DNA depletion syndrome.
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.06.028
Free light chains in cerebrospinal fluid of multiple sclerosis patients negative for IgG oligoclonal bands
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.06.016
Antibody Level against HBV after Hepatitis B Vaccination and Sero-Prevalence of HBV in Children in Addis Ababa, Ethiopia
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1167
Evaluation of estimated GFR using a point of care (POC) measure of creatinine in patients with iohexol determinate GFR
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1407
Priority role of the laboratory in the prevention of renal lithiasis and its results
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.976
Main interferences and irregularities in the protein pattern: Analyzing non-monoclonal peaks in capillary electrophoresis
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.641
Real-time monitoring of drug-laboratory test interactions with an automated decision support application
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1118
Evaluation of parathormone and 25-hydroxyvitamin D status in a large cohort of Belgian children
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.347
Are variations of glycated hemoglobin given by the freestyle device accurate
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.614
24,25(OH)2D as a marker of vitamin D deficiency in children: A retrospective analysis on 1200 cases
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.352
Evaluation of analytical performance of qualitative and semi-quantitative assays in the clinical laboratory.
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.07.018
Paediatric reference intervals for bone alkaline phosphatase on Liaison° XL (Diasorin°)
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1246
The diagnostic accuracy of hematological laboratory parameters in the diagnosis of acute appendicitis in the adult emergency department population
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.798
Impact of the implementation of high-sensitivity troponin I on the requests of cardiac biomarkers
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.354
The importance of serum paraoxonase, arylesterase and ischemia modified albumin levels in evaluation of patients with bell palsy
来源期刊:Clinica Chimica ActaDOI:10.1016/j.cca.2019.03.927
Plasmodium malariae case report: Usefulness of SYSMEX-XN “PRBC” flag
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.506
Massive intravascular hemolysis due to clostridium perfringens septicemia: A case report
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.423
Measurement of free testosterone, androstenedione, and 17-hydroxyprogesterone: Comparison of current laboratory methods
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1498
Evaluation of VACUETTE® cat serum fast separator blood collection tube for routine chemistry assays
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.542
Use of non invasive prenatal fetal blood group genotyping in the monitoring of allo-immunized pregnant women: Experience of the french national center for perinatal hemobiology (CNRHP)
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1260
Study of the precision of a measurement procedure in a clinical laboratory
来源期刊:Clinica Chimica ActaDOI:10.1016/J.CCA.2019.03.1339