The field of cellular and molecular bioengineering seeks to understand, so that we may ultimately control, the mechanical, chemical, and electrical processes of the cell. A key challenge in improving human health is to understand how cellular behavior arises from molecular-level interactions. CMBE, an official journal of the Biomedical Engineering Society, publishes original research and review papers in the following seven general areas:Molecular: DNA-protein/RNA-protein interactions, protein folding and function, protein-protein and receptor-ligand interactions, lipids, polysaccharides, molecular motors, and the biophysics of macromolecules that function as therapeutics or engineered matrices, for example.Cellular: Studies of how cells sense physicochemical events surrounding and within cells, and how cells transduce these events into biological responses. Specific cell processes of interest include cell growth, differentiation, migration, signal transduction, protein secretion and transport, gene expression and regulation, and cell-matrix interactions.Mechanobiology: The mechanical properties of cells and biomolecules, cellular/molecular force generation and adhesion, the response of cells to their mechanical microenvironment, and mechanotransduction in response to various physical forces such as fluid shear stress.Nanomedicine: The engineering of nanoparticles for advanced drug delivery and molecular imaging applications, with particular focus on the interaction of such particles with living cells. Also, the application of nanostructured materials to control the behavior of cells and biomolecules.
细胞和分子生物工程领域寻求理解细胞的机械、化学和电学过程，以便我们可以最终控制这些过程。改善人类健康的一个关键挑战是了解细胞行为是如何从分子水平的相互作用中产生的。CMBE是生物医学工程学会的官方期刊，发表以下七个领域的原创研究和综述论文：分子：DNA-蛋白质/RNA-蛋白质相互作用、蛋白质折叠和功能、蛋白质-蛋白质和受体-配体相互作用、脂质、多糖、分子马达以及例如作为治疗剂或工程基质的大分子的生物物理学。研究细胞如何感知细胞周围和内部的物理化学事件，以及细胞如何将这些事件转化为生物反应。感兴趣的特定细胞过程包括细胞生长、分化、迁移、信号转导、蛋白质分泌和转运、基因表达和调节以及细胞-基质相互作用。细胞和生物分子的机械特性、细胞/分子力的产生和粘附、细胞对其机械微环境的响应以及对各种物理力（如流体剪切应力）的机械转导。纳米医学：用于高级药物递送和分子成像应用的纳米颗粒的工程，特别关注这种颗粒与活细胞的相互作用。此外，纳米结构材料在控制细胞和生物分子行为方面的应用。
Cell–Cell Mechanical Communication in Cancer
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00564-X
Cell Subtypes Within the Liver Microenvironment Differentially Interact with Lipid Nanoparticles
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00573-4
A Novel Nanoconjugate of Landomycin A with C60 Fullerene for Cancer Targeted Therapy: In Vitro Studies
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-0548-5
How Tumor Cells Can Make Use of Interstitial Fluid Flow in a Strategy for Metastasis
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00569-0
Dynamics of Non-Canonical Amino Acid-Labeled Intra- and Extracellular Proteins in the Developing Mouse.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00592-1
The TRPV4-TAZ Mechanotransduction Signaling Axis in Matrix Stiffness- and TGFβ1-Induced Epithelial-Mesenchymal Transition
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00565-W
Examination of Hydrogels and Mesenchymal Stem Cell Sources for Bioprinting of Artificial Osteogenic Tissues
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00588-x
Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-018-00562-z
Dual Inhibitors-Loaded Nanotherapeutics that Target Kinase Signaling Pathways Synergize with Immune Checkpoint Inhibitor
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00576-1
Optogenetic Repressors of Gene Expression in Yeasts Using Light-Controlled Nuclear Localization.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00598-9
Hierarchical-Clustering, Scaffold-Mining Exercises and Dynamics Simulations for Effectual Inhibitors Against Lipid-A Biosynthesis of Helicobacter pylori
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00572-5
Mechanical Characterization of 3D Ovarian Cancer Nodules Using Brillouin Confocal Microscopy
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00570-7
Tumor Cell Mechanosensing During Incorporation into the Brain Microvascular Endothelium.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00591-2
Degradation and Remodeling of Epitaxially Grown Collagen Fibrils
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-0547-6
Endothelial Cell Biomechanical Responses are Dependent on Both Fluid Shear Stress and Tensile Strain.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/S12195-019-00585-0
Injectable, Hyaluronic Acid-Based Scaffolds with Macroporous Architecture for Gene Delivery.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00593-0
Ciliotherapy Treatments to Enhance Biochemically- and Biophysically-Induced Mesenchymal Stem Cell Osteogenesis: A Comparison Study
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00561-0
Biofabricated Humanized Insulin Producing Neo-Organs Generates Secondary Neo-Organoids Through Ectopic Transplantation
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00586-z
Probing Single-Cell Mechanical Allostasis Using Ultrasound Tweezers
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00578-z
Carrier-Free CXCR4-Targeted Nanoplexes Designed for Polarizing Macrophages to Suppress Tumor Growth.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00589-w
Selectin-Targeting Peptide–Glycosaminoglycan Conjugates Modulate Neutrophil–Endothelial Interactions
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-018-0555-6
Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00571-6
A Multiscale Model for Recruitment Aggregation of Platelets by Correlating with In Vitro Results.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/S12195-019-00583-2
Type I Diabetes Delays Perfusion and Engraftment of 3D Constructs by Impinging on Angiogenesis; Which can be Rescued by Hepatocyte Growth Factor Supplementation
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00574-3
Mechanical Response of an Epithelial Island Subject to Uniaxial Stretch on a Hybrid Silicone Substrate
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00560-1
Inference of Cellular Immune Environments in Sputum and Peripheral Blood Associated with Acute Exacerbations of COPD
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00567-2
Correction to: Methods for 20S Immunoproteasome and 20S Constitutive Proteasome Determination Based on SPRI Biosensors
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00559-8
Coencapsulation of ISCs and MSCs Enhances Viability and Function of both Cell Types for Improved Wound Healing
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00582-3
Cyclic Stretching of Fibrotic Microtissue Array for Evaluation of Anti-Fibrosis Drugs
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00590-3
ROS and NO Dynamics in Endothelial Cells Exposed to Exercise-Induced Wall Shear Stress
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00557-W
Human Amniotic Membrane as a Matrix for Endothelial Differentiation of VEGF-Treated Dental Stem Cells
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00596-x
Shear Stress in Bone Marrow has a Dose Dependent Effect on cFos Gene Expression in In Situ Culture.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/s12195-019-00594-z
Dynamic Model of Protease State and Inhibitor Trafficking to Predict Protease Activity in Breast Cancer Cells
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00580-5
Modeling DNA Unwinding by AddAB Helicase–Nuclease and Modulation by Chi Sequences: Comparison with AdnAB and RecBCD
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00563-Y
Effects of Rolling-Sliding Mechanical Stimulation on Cartilage Preserved In Vitro.
来源期刊：Cellular and molecular bioengineeringDOI：10.1007/S12195-019-00584-1
Identifying Key Pathways and Components in Chemokine-Triggered T Lymphocyte Arrest Dynamics Using a Multi-Parametric Global Sensitivity Analysis
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00575-2
Ultrasound Enhanced Anti-tumor Effect of Temozolomide in Glioblastoma Cells and Glioblastoma Mouse Model
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-0553-8
Correction to: Translating Mechanobiology to the Clinic: A Panel Discussion from the 2018 CMBE Conference
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-00558-9
Correction to: Type I Diabetes Delays Perfusion and Engraftment of 3D Constructs by Impinging on Angiogenesis; Which can be Rescued by Hepatocyte Growth Factor Supplementation
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/s12195-019-00595-y
Platelet-Derived Growth Factor Receptor-α and β are Involved in Fluid Shear Stress Regulated Cell Migration in Human Periodontal Ligament Cells
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-018-0546-7
Differential Effects of the Antioxidants N-Acetylcysteine and Pyrrolidine Dithiocarbamate on Mesenchymal Stem Cell Chondrogenesis
来源期刊：Cellular and Molecular BioengineeringDOI：10.1007/S12195-019-00566-3
