Cell Stem Cell is a broad-spectrum journal that covers the entire spectrum of stem cell biology. Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue-specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem-cell-based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource-based innovations. We will consider studies from any model system that provides insights into stem cell biology, and we encourage submissions on human stem cells.Cell Stem Cell publishes research reports describing novel results of unusual significance in all areas of stem cell research. Each issue also contains a wide variety of review and analysis articles covering topics relevant to stem cell research ranging from basic biological advances to ethical, policy, and funding issues.
《细胞干细胞》是一本涵盖了干细胞生物学的全方位的期刊。主题包括胚胎干细胞、多能性、生殖系干细胞、组织特异性干细胞、干细胞分化、表观遗传学、干细胞基因组学和系统生物学、基因组重编程、癌症干细胞、干细胞利基、基于干细胞的疾病模型、核转移技术、生物工程、药物发现、干细胞的体内成像、治疗应用、再生医学、临床和转化见解、干细胞研究政策、伦理问题和技术或资源创新。我们将考虑任何模型系统的研究，提供对干细胞生物学的见解，我们鼓励提交关于人类干细胞的研究报告。细胞干细胞发表研究报告，描述在干细胞研究的所有领域具有不同寻常意义的新结果。每期还包含各种各样的评论和分析文章，涵盖了从基本生物学进展到伦理、政策和资金问题等与干细胞研究相关的主题。
Targeting Cancer Stemness in the Clinic: From Hype to Hope.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.11.017
hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.015
Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.05.011
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
来源期刊：Cell Stem CellDOI：10.1016/j.stem.2018.12.013
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.04.004
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.014
Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.11.021
TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.05.019
Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.011
AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.10.011
Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance
来源期刊：Cell Stem CellDOI：10.1016/j.stem.2019.02.004
Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.03.022
Human Pluripotent Stem Cell-Derived Cardiovascular Cells: From Developmental Biology to Therapeutic Applications.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.07.010
MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo
来源期刊：Cell Stem CellDOI：10.1016/j.stem.2019.01.013
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.012
Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.11.003
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.09.003
Cellular Plasticity in Intestinal Homeostasis and Disease.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.11.019
A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.06.008
IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.10.016
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.11.016
Asymmetric Centromeres Differentially Coordinate with Mitotic Machinery to Ensure Biased Sister Chromatid Segregation in Germline Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.08.014
Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.11.015
Mitigating Antagonism between Transcription and Proliferation Allows Near-Deterministic Cellular Reprogramming.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.08.005
Lentiviral Gene Therapy in HSCs Restores Lineage-Specific Foxp3 Expression and Suppresses Autoimmunity in a Mouse Model of IPEX Syndrome.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.003
Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.11.007
Transplantation of Human Brain Organoids: Revisiting the Science and Ethics of Brain Chimeras.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.09.002
Design Approaches for Generating Organ Constructs.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.05.016
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
来源期刊：Cell Stem CellDOI：10.1016/j.stem.2018.12.001
Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.09.004
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.03.011
Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.06.013
Competition for Food Drives Stem Cell Fate in Facultative Niches.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2018.12.010
Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
来源期刊：Cell Stem CellDOI：10.1016/j.stem.2019.10.005
Breakthrough Moments: Organoid Models of Cancer.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.05.006
Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.08.008
Directly Reprogrammed Neurons Still Have Some Growing Up to Do.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.06.005
Stem Cell Aging? Blame It on the Niche.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.02.011
Putting Stem Cells on a Low-Fat Diet Switches Their Pluripotent State.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.06.002
TREMendous Macrophages Inhibit Hair Growth.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.03.014
RALying Regeneration through Wnt Internalization in Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.03.008
Cutting Off Leukemogenesis: Hydra-like Plasticity of Mature Leukemic Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.07.005
Engineered Stem Cells Provide Cancer-Killing iNKT Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.09.005
Ancestry Tracing: Uncovering a Gliomagenesis Master Regulator.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.04.006
The Seed Tends to the Soil: Hair Follicle Stem Cells Remodel Their Lymphatic Niche.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.11.009
Mutualism in the Marrow.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.11.007
Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.03.001
Gene Editing Expands the Donor Pool for CCR5-Negative Stem Cell Transplants.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.11.006
We Could Use More Tolerance: Role of Intestinal-Allograft-Derived Human Stem Cells.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.01.009
Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection.
来源期刊：Cell stem cellDOI：10.1016/j.stem.2019.08.006
