Published since 1929, the Canadian Journal of Physiology and Pharmacology is a monthly journal that reports current research in all aspects of physiology, nutrition, pharmacology, and toxicology, contributed by recognized experts and scientists. It publishes symposium reviews and award lectures and occasionally dedicates entire issues or portions of issues to subjects of special interest to its international readership. The journal periodically publishes a “Made In Canada” special section that features invited review articles from internationally recognized scientists who have received some of their training in Canada.
《加拿大生理学和药理学杂志》（Canadian Journal of Physiology and Pharmacology）自1929年出版以来，是一份月刊杂志，报告生理学、营养学、药理学和毒理学各方面的最新研究，由公认的专家和科学家撰写。它出版专题讨论会评论和颁奖演讲，偶尔将整个问题或问题的一部分专门用于其国际读者特别感兴趣的主题。该杂志定期出版一个“加拿大制造”的特别部分，邀请在加拿大接受过一些培训的国际知名科学家发表评论文章。
Molecular hydrogen: potential in mitigating oxidative-stress-induced radiation injury 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0604
Sustained quality improvement in outcomes of preterm neonates with a gestational age less than 29 weeks: results from the Evidence-based Practice for Improving Quality Phase 3 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0439
Effects of silica nanoparticles on endolysosome function in primary cultured neurons 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0401
Restoration of skeletal muscle homeostasis by hydrogen sulfide during hyperhomocysteinemia-mediated oxidative/ER stress condition 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0501
A sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin comparison with insulin shows important effects on Zn2+-transporters in cardiomyocytes from insulin-resistant metabolic syndrome rats through inhibition of oxidative stress 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0466
Effect of febuxostat on biochemical parameters of hyperlipidemia induced by a high-fat diet in rabbits.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0731
Effects of Somatostatin, Curcumin and Quercetin on the fatty acid profile of breast cancer cell membranes.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0352
Role of Wnt/β-catenin pathway agonist SKL2001 in Caerulein-induced acute pancreatitis.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0226
MONOAMINE OXIDASE IS A SOURCE OF OXIDATIVE STRESS IN OBESE PATIENTS WITH CHRONIC INFLAMMATION.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0028
Apoptosis perturbations and expression of regulatory inflammatory factors in cisplatin-depleted rat livers under l-arginine protection.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0706
Mechanisms for the transition from physiological to pathological cardiac hypertrophy.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0566
Melatonin treatment affects changes in adrenal gene expression of catecholamine biosynthesizing enzymes and norepinephrine transporter in the rat model of chronic-stress-induced depression.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0612
Intra-articular injection of hydrogen sulfide decreased the progression of gonarthrosis.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0574
High throughput screening reveals no significant changes in protein synthesis, processing, and degradation machinery during passaging of mesenchymal stem cells 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0553
Liver mitochondrial respiratory plasticity and oxygen uptake evoked by cobalt chloride in rats with low and high resistance to extreme hypobaric hypoxia.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0642
Salvianolic acid B exerts a protective effect in acute liver injury by regulating the Nrf2/HO-1 signaling pathway.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0349
Telomere length and age-dependent telomere attrition: the blood-and-muscle model 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0582
An updated normative data set from the autonomic reflex screen representative of Southwestern Ontario.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0611
Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0374
Contributions of Rho-kinase and AMP-related kinase signaling pathways to responses mediated by endothelium-derived contracting factors in diabetic rat aorta.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0698
Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0024
Oral ethinylestradiol-levonorgestrel normalizes fructose-induced hepatic lipid accumulation and glycogen depletion in female rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0037
INHIBITION OF GASOTRANSMITTERS PRODUCTION AND CALCIUM INFLUX AFFECT CARDIODYNAMIC VARIABLES AND CARDIAC OXIDATIVE STRESS IN PROPOFOL-ANAESTHETIZED WISTAR MALE RATS.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0719
Resveratrol prevents palmitic acid induced cardiomyocyte contractile impairment.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0051
Hemoglobin oxygen saturation targets in the neonatal intensive care unit: Is there a light at the end of the tunnel? 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0376
Promotion of whole blood rheology after vitamin C supplementation: Focus on red blood cells.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0735
Stimulation of the endogenous hydrogen sulfide synthesis suppresses oxidative-nitrosative stress and restores endothelial-dependent vasorelaxation in old rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0411
The role of aspirin and inflammation on reproduction: the EAGeR trial 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0368
Amelioration of estrogen-induced endometrial hyperplasia in female rats by hemin via heme-oxygenase-1 expression, suppression of iNOS, p38MAPK and Ki67.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0287
Application of real-time contrast-enhanced ultrasound in differential diagnosis of liver malignancies.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0404
The effects of acute Sumatriptan treatment on renal ischemia/reperfusion injury in rat and the possible involvement of nitric oxide.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0301
Cellular mechanisms promoting cachexia and how they are opposed by sirtuins 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0479
Altered K+ current profiles underlie cardiac action potential shortening in hyperkalemia and β adrenergic stimulation.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0056
The effects of dietary flaxseed on cardiac arrhythmias and claudication in patients with peripheral arterial disease 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0280
VASCULAR DYSFUNCTION FOLLOWING BREATH-HOLD DIVING.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0341
Relationship between aldose reductase enzyme and the signaling pathway of protein kinase C in the in vitro diabetic retinopathy model.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0211
Effects of different concentrations of desflurane on index of cardiac electrophysiological balance in gynecologic surgery patients.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0290
Ameliorative effect of low-dose spironolactone on obesity and insulin resistance is through replenishment of estrogen in ovariectomized rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0416
Modulation of oxidative/nitrosative stress and inflammatory response by rapamycin in target and distant organs in rats exposed to hindlimb ischemia/reperfusion: The role of mTOR.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0394
Sorafenib-loaded PAMAM dendrimer attenuates liver fibrosis and its complications in bile-duct-ligated rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0141
Involvement of leukotriene pathway in the development of sevoflurane-induced pica in rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0494
The contribution of phosphodiesterases to cardiac dysfunction in rats with metabolic syndrome induced by a high-carbohydrate diet.
来源期刊：Canadian Journal of Physiology and PharmacologyDOI：10.1139/CJPP-2019-0006
Cardiovascular regulation: associations between exercise and head-up tilt.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2018-0742
Therapeutic potential of selanyl amide derivatives in the in vitro anticholinesterase activity and in in vivo anti-amnesic action.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0291
The effect of apelin-13 on gastric ischemia/reperfusion injury: The roles of sensory nerves and nervus vagus.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0502
Extracellular and intracellular tumor necrosis factor alpha modulates cytosolic and nuclear calcium in human cardiovascular cells 1.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0070
Sodium nitroprusside attenuates hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats through the inhibition of overexpression of AT1 receptor, cell cycle proteins and c-Src/growth factor receptor signaling pathways.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0338
Effect of Distal Esophageal Irritation on the Changes of Cystometry Parameters to Esophagus and Colon Distentions in Rats.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0122
Mechanisms of NADPH-cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line.
来源期刊：Canadian journal of physiology and pharmacologyDOI：10.1139/cjpp-2019-0586
